Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Abigail L, Reens"'
Autor:
Abigail L. Reens, Casey M. Cosetta, Russell Saur, Olivia Trofimuk, Sarah L. Brooker, Martin L. Lee, Adam K. Sun, Gregory J. McKenzie, Julie E. Button
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTPrecision engineering of the gut microbiome holds promise as an effective therapeutic approach for diseases associated with a disruption in this microbial community. Engrafting a live biotherapeutic product (LBP) in a predictable, controllabl
Externí odkaz:
https://doaj.org/article/d8ad5f1a61ed40549147fcb07f5440db
Autor:
Abigail L. Reens, Damien J. Cabral, Xue Liang, James E. Norton, Alex G. Therien, Daria J. Hazuda, Gokul Swaminathan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Emerging evidence in clinical and preclinical studies indicates that success of immunotherapies can be impacted by the state of the microbiome. Understanding the role of the microbiome during immune-targeted interventions could help us understand het
Externí odkaz:
https://doaj.org/article/f6b60dccb4494d5f9ae6e9a732fc83c4
Autor:
Gokul Swaminathan, Michael Citron, Jianying Xiao, James E. Norton, Abigail L. Reens, Begüm D. Topçuoğlu, Julia M. Maritz, Keun-Joong Lee, Daniel C. Freed, Teresa M. Weber, Cory H. White, Mahika Kadam, Erin Spofford, Erin Bryant-Hall, Gino Salituro, Sushma Kommineni, Xue Liang, Olga Danilchanka, Jane A. Fontenot, Christopher H. Woelk, Dario A. Gutierrez, Daria J. Hazuda, Geoffrey D. Hannigan
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1340 (2021)
Emerging evidence demonstrates a connection between microbiome composition and suboptimal response to vaccines (vaccine hyporesponse). Harnessing the interaction between microbes and the immune system could provide novel therapeutic strategies for im
Externí odkaz:
https://doaj.org/article/c57141bfb4b545c0b73222a00565d3e1
Autor:
Abigail L Reens, Amy L Crooks, Chih-Chia Su, Toni A Nagy, David L Reens, Jessica D Podoll, Madeline E Edwards, Edward W Yu, Corrella S Detweiler
Publikováno v:
PLoS Pathogens, Vol 14, Iss 6, p e1007115 (2018)
Bacterial efflux pumps transport small molecules from the cytoplasm or periplasm outside the cell. Efflux pump activity is typically increased in multi-drug resistant (MDR) pathogens; chemicals that inhibit efflux pumps may have potential for antibio
Externí odkaz:
https://doaj.org/article/cc8650ba36e94f3ea9173a0d6f6850bd
Autor:
Julie E. Button, Chloe A. Autran, Abigail L. Reens, Casey M. Cosetta, Steven Smriga, Megan Ericson, Jessica V. Pierce, David N. Cook, Martin L. Lee, Adam K. Sun, Amin M. Alousi, Andrew Y. Koh, David J. Rechtman, Robert R. Jenq, Gregory J. McKenzie
Publikováno v:
Cell hostmicrobe. 30(5)
Predictable and sustainable engraftment of live biotherapeutic products into the human gut microbiome is being explored as a promising way to modulate the human gut microbiome. We utilize a synbiotic approach pairing the infant gut microbe Bifidobact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e55940937692348701cea11f6485db8
https://pubmed.ncbi.nlm.nih.gov/35504279
https://pubmed.ncbi.nlm.nih.gov/35504279
Autor:
Xue Liang, Begüm D. Topçuoğlu, Erin Spofford, Julia M. Maritz, Sushma Kommineni, Cory H. White, Olga Danilchanka, Daria J. Hazuda, Geoffrey D. Hannigan, Teresa M. Weber, Michael P. Citron, Jianying Xiao, Christopher H. Woelk, Daniel C. Freed, Erin Bryant-Hall, Keun-Joong Lee, Jane Fontenot, Gokul Swaminathan, Gino Salituro, Dario A. Gutierrez, Mahika Kadam, James E. Norton, Abigail L. Reens
Publikováno v:
Vaccines
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1340, p 1340 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1340, p 1340 (2021)
Emerging evidence demonstrates a connection between microbiome composition and suboptimal response to vaccines (vaccine hyporesponse). Harnessing the interaction between microbes and the immune system could provide novel therapeutic strategies for im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0cf1d7a92a3cd65deaed86a86d25fe
Autor:
J. Richard Miller, Bo-Sheng Pan, Abigail L. Reens, Larissa Rakhilina, An Chi, My Sam Mansueto
Publikováno v:
J Biol Chem
Spleen tyrosine kinase (SYK) is a signaling node in many immune pathways and comprises two tandem Src homology (SH) 2 domains, an SH2-kinase linker, and a C-terminal tyrosine kinase domain. Two prevalent models of SYK activation exist. The “OR-gate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645091c80674c1748129dd35e9315ab9
https://doi.org/10.1074/jbc.ra119.008045
https://doi.org/10.1074/jbc.ra119.008045
Publikováno v:
Infect Immun
To survive and replicate during infection, pathogens utilize different carbon and energy sources depending on the nutritional landscape of their host microenvironment. Salmonella enterica serovar Typhimurium is an intracellular bacterial pathogen tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e77f7f6966fd236d52a6075c75d7527
https://doi.org/10.1128/iai.00776-19
https://doi.org/10.1128/iai.00776-19
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Salmonella enterica are natural bacterial pathogens of humans and animals that cause systemic infection or gastroenteritis. During systemic infection, Salmonella generally reside within professional phagocytes, typically macrophages, whereas gastroen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fa6552177257b64739db827cc99828
https://doi.org/10.1128/aac.01536-19
https://doi.org/10.1128/aac.01536-19
Publikováno v:
Antimicrobial Agents and Chemotherapy
Salmonella enterica is a natural bacterial pathogen of humans and animals that causes systemic infection or gastroenteritis. During systemic infection, Salmonella generally resides within professional phagocytes, typically macrophages, whereas gastro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92381e88aa896646a660c95aa6e226dc
https://pubmed.ncbi.nlm.nih.gov/31591121
https://pubmed.ncbi.nlm.nih.gov/31591121