Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Abigail K. Brown"'
Autor:
Amanda J. Audesse, Galina Karashchuk, Zachary A. Gardell, Nelli S. Lakis, Sun Y. Maybury‐Lewis, Abigail K. Brown, Dena S. Leeman, Yee Voan Teo, Nicola Neretti, Douglas C. Anthony, Alexander S. Brodsky, Ashley E. Webb
Publikováno v:
Aging and Cancer, Vol 2, Iss 4, Pp 137-159 (2021)
Abstract Background Glioblastoma (GBM) is an aggressive, age‐associated malignant glioma that contains populations of cancer stem cells. These glioma stem cells (GSCs) evade therapeutic interventions and repopulate tumors due to their existence in
Externí odkaz:
https://doaj.org/article/dfb2b7f31be3409ab6907814e72b7ff3
Autor:
Anna Sloutskin, Shleshma Dhakal, Mitchell Yeary, Ashley E. Webb, Sun Y. Maybury-Lewis, Tamar Juven-Gershon, Abigail K. Brown
Publikováno v:
Aging Cell
Neural stem cells (NSCs) in the adult and aged brain are largely quiescent, and require transcriptional reprogramming to re‐enter the cell cycle. However, the mechanisms underlying these changes and how they are altered with age remain undefined. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e684d2540f1e6ebe2a38eaef8eeef535
http://europepmc.org/articles/PMC8590101
http://europepmc.org/articles/PMC8590101
FOXO transcription factors are critical for cellular homeostasis and have been implicated in longevity in several species. Yet how these factors directly affect aging, particularly in humans, is not well understood. Here, we take an integrated multi-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a125f93425e1925891ae10a2637416e
https://doi.org/10.1101/2021.04.06.438676
https://doi.org/10.1101/2021.04.06.438676
Autor:
Abigail K. Brown, Ashley E. Webb
Forkhead box O (FOXO) transcription factors are central regulators of cellular homeostasis. FOXOs respond to a wide range of external stimuli, including growth factor signaling, oxidative stress, genotoxic stress, and nutrient deprivation. These sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15443ec213295dfcb4d14e76638baa2d
https://doi.org/10.1016/bs.ctdb.2017.10.006
https://doi.org/10.1016/bs.ctdb.2017.10.006
Autor:
Audesse, Amanda J., Karashchuk, Galina, Gardell, Zachary A., Lakis, Nelli S., Maybury‐Lewis, Sun Y., Brown, Abigail K., Leeman, Dena S., Teo, Yee Voan, Neretti, Nicola, Anthony, Douglas C., Brodsky, Alexander S., Webb, Ashley E.
Publikováno v:
Aging & Cancer; Dec2021, Vol. 2 Issue 4, p137-159, 23p
Autor:
Saghi Ghaffari
Forkhead FOXO Transcription Factors in Development and Disease, Volume 127, the latest release in the Current Topics in Developmental Biology series, provides a comprehensive set of reviews on transcription factors FOXO and their various functions in