Zobrazeno 1 - 4
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pro vyhledávání: '"Abigail J. Halmes"'
Autor:
Hai Qian, Douglas G. Ivanoff, Nathan S. Purwanto, Abigail J. Halmes, Jeffrey S. Moore, Nancy R. Sottos
Publikováno v:
Chem. 7:1080-1091
Summary To address hysteretic or irreversible mechanochromism found in most bond-scission-based mechanophores, we developed a new family of mechanophores based on the oxazine (OX) structural motif. Three OX regioisomers differing in their point of at
Autor:
Yang Song, Giuseppe Léonardo Licari, Jeffrey S. Moore, Qian Chen, Edwin G. Moore, Emad Tajkhorshid, Chad M. Rienstra, John W. Smith, Abigail J. Halmes, Xing Jiang
Publikováno v:
ACS Macro Letters. 8:1365-1371
Protein aggregation is implicated in multiple deposition diseases including Alzheimer’s Disease, which features the formation of toxic aggregates of amyloid beta (Aβ) peptides. Many inhibitors have been developed to impede or reverse Aβ aggregati
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(21)
While study in the field of polymer mechanochemistry has yielded mechanophores that perform various chemical reactions in response to mechanical stimuli, there is not yet a triggering method compatible with biological systems. Applications such as us
Autor:
Jeffrey S. Moore, Maxwell J. Robb, Scott R. White, Abigail J. Halmes, Tae Ann Kim, Nancy R. Sottos
Publikováno v:
Journal of the American Chemical Society. 138(38)
Transformation of naphthopyran into a colored merocyanine species in polymeric materials is achieved using mechanical force. We demonstrate that the mechanochemical reactivity of naphthopyran is critically dependent on the regiochemistry, with only o