Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Abigail Hielscher"'
Publikováno v:
BMC Cell Biology, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background Carcinoma associated fibroblasts (CAFs or myofibroblasts) are activated fibroblasts which participate in breast tumor growth, angiogenesis, invasion, metastasis and therapy resistance. As such, recent efforts have been directed to
Externí odkaz:
https://doaj.org/article/4bc8fed3ee024d54922640378b5ccc49
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172067 (2017)
The extracellular matrix (ECM) is abnormal in breast tumors and has been reported to contribute to breast tumor progression. One factor, which may drive ongoing matrix synthesis in breast tumors, is the loss of stromal caveolin-1 (cav-1), a scaffoldi
Externí odkaz:
https://doaj.org/article/963ce442bec143fcaf87a8ec1031f312
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147600 (2016)
The extracellular matrix (ECM) has been demonstrated to facilitate angiogenesis. In particular, fibronectin has been documented to activate endothelial cells, resulting in their transition from a quiescent state to an active state in which the cells
Externí odkaz:
https://doaj.org/article/e5ef70f3b12e4884a9b7b2f5805a5a8e
Publikováno v:
BMC Cell Biology, Vol 18, Iss 1, Pp 1-17 (2017)
BMC Cell Biology
BMC Cell Biology
Background Carcinoma associated fibroblasts (CAFs or myofibroblasts) are activated fibroblasts which participate in breast tumor growth, angiogenesis, invasion, metastasis and therapy resistance. As such, recent efforts have been directed toward unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0eb2954f9671487456f5fcaf19c62d4
http://link.springer.com/article/10.1186/s12860-017-0151-y
http://link.springer.com/article/10.1186/s12860-017-0151-y
Publikováno v:
Journal of Cancer
Fibronectin is a matrix glycoprotein which has not only been found to be over-expressed in several cancers, but has been shown to participate in several steps of tumorigenesis. The purpose of this review is to illustrate how aberrant fibronectin expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab4f62d1b0daa324d0e4c908cb67b4f
https://doi.org/10.7150/jca.16901
https://doi.org/10.7150/jca.16901
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70fc6102a7f5fe36758322eb236b5c91
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb679
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb679
Publikováno v:
Journal of Visualized Experiments.
The goal of this procedure was to harvest the #4 abdominal mammary glands from female nulliparous mice in order to assess ECM expression and ductal architecture. Here, a small pocket below the skin was created using Mayo scissors, allowing separation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0730f3333a1e5abb9bc7fae81db158ca
https://doi.org/10.3791/56512-v
https://doi.org/10.3791/56512-v
Autor:
Sharon Gerecht, Abigail Hielscher
Publikováno v:
Cancer Research. 72:6089-6096
A major paradigm shift in cancer research is the emergence of multidisciplinary approaches to investigate complex cell behaviors, to elucidate regulatory mechanisms and to identify therapeutic targets. Recently, efforts are focused on the engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524ae083589af89f74ea5d232e2b5e2e
https://doi.org/10.1158/0008-5472.can-12-2773
https://doi.org/10.1158/0008-5472.can-12-2773
Autor:
Abigail Hielscher, Ayesha Patel
Publikováno v:
Journal of Cancer Prevention & Current Research. 2
Breast cancer is a debilitating disease, which, according to the National Breast Cancer Foundation will affect one in eight women. While the etiology of the disease is multi factorial, angiogenesis, the growth of new vessels from pre-existing vessels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dc1e2647f98c6fff3367075bb70d89d
https://doi.org/10.15406/jcpcr.2015.02.00059
https://doi.org/10.15406/jcpcr.2015.02.00059
Autor:
Abigail Hielscher, Sharon Gerecht
Hypoxia is a feature of all solid tumors, contributing to tumor progression and therapy resistance. Through stabilization of the hypoxia-inducible factor 1 alpha (HIF-1α), hypoxia activates the transcription of a number of genes that sustain tumor p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd96c8769adb89e3b1bf34017e9f708
https://europepmc.org/articles/PMC4339408/
https://europepmc.org/articles/PMC4339408/
