Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Abigail E. Loneker"'
Autor:
Jessica Llewellyn, Caterina Fede, Abigail E. Loneker, Chet S. Friday, Michael W. Hast, Neil D. Theise, Emma E. Furth, Maria Guido, Carla Stecco, Rebecca G. Wells
Publikováno v:
JHEP Reports, Vol 5, Iss 9, Pp 100760- (2023)
Background & Aims: Glisson’s capsule is the interstitial connective tissue that surrounds the liver. As part of its normal physiology, it withstands significant daily changes in liver size. The pathophysiology of the capsule in disease is not well
Externí odkaz:
https://doaj.org/article/f72ca49d744e4847ab46882bd3e9e617
Autor:
Abigail E. Loneker, Rebecca G. Wells
Publikováno v:
Cancers, Vol 13, Iss 17, p 4275 (2021)
Hepatocellular carcinoma (HCC) is the second most deadly primary cancer in the world and is thus a major global health challenge. HCC primarily develops in patients with an underlying chronic liver disease, the vast majority with advanced cirrhosis,
Externí odkaz:
https://doaj.org/article/a28641efb8b14b579e94378a7de1d25d
Autor:
Abigail E. Loneker, Farid Alisafaei, Aayush Kant, David Li, Paul A. Janmey, Vivek B. Shenoy, Rebecca G. Wells
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Matrix stiffening and external mechanical stress have been linked to disease and cancer development in multiple tissues, including the liver, where cirrhosis (which increases stiffness markedly) is the major risk factor for hepatocellular carcinoma.
Autor:
Jessica Llewellyn, Caterina Fede, Abigail E. Loneker, Chet S. Friday, Michael W. Hast, Neil D. Theise, Emma E. Furth, Maria Guido, Carla Stecco, Rebecca G. Wells
Background and AimsGlisson’s capsule is the interstitial connective tissue that surrounds the liver. As part of its normal physiology, it withstands significant daily changes in liver size. The pathophysiology of the capsule in disease is not well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::035868f4c3db7fa648f165d0167dc358
https://doi.org/10.1101/2022.08.28.505570
https://doi.org/10.1101/2022.08.28.505570
Autor:
Abigail E. Loneker, Farid Alisafaei, Aayush Kant, Paul A. Janmey, Vivek B. Shenoy, Rebecca G. Wells
Matrix stiffening and external mechanical stress have been linked to disease and cancer development in multiple tissues, including the liver, where cirrhosis (which increases stiffness markedly) is the major risk factor for hepatocellular carcinoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6561766b492da579edcd45b93259964
https://doi.org/10.1101/2022.08.27.505524
https://doi.org/10.1101/2022.08.27.505524
Autor:
Jessica Llewellyn, Caterina Fede, Abigail E. Loneker, Chet S. Friday, Michael W. Hast, Neil D. Theise, Emma E. Furth, Maria Guido, Carla Stecco, Rebecca G. Wells
Publikováno v:
JHEP Reports. :100760
Autor:
Rebecca G. Wells, Abigail E. Loneker
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4275, p 4275 (2021)
Cancers, Vol 13, Iss 4275, p 4275 (2021)
Simple Summary Hepatocellular carcinoma (HCC) is a deadly primary liver cancer that most often develops in a cirrhotic (highly scarred) liver. Cirrhosis is associated with large-scale mechanical changes in the liver, with increases in stiffness to le
Autor:
Denver M. Faulk, Arush Kalra, Alan Nugent, Antonio D'Amore, Doug Bernstein, Abigail E. Loneker, Samuel K. Luketich
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:659-671
In pediatric cardiovascular surgery, there is a significant need for vascular prostheses that have the potential to grow with the patient following implantation. Current clinical options consist of nonexpanding conduits, requiring repeat surgeries as
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 35(23)
At the plasma membrane interface, cells use various adhesions to sense their extracellular environment. These adhesions facilitate the transmission of mechanical signals that dictate cell behavior. This review discusses the mechanisms by which these
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:957-965
Whole organ engineering and cell-based regenerative medicine approaches are being investigated as potential therapeutic options for end-stage liver failure. However, a major challenge of these strategies is the loss of hepatic specific function after