Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Abigail E Overacre-Delgoffe"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b4dc55bd058e460e9a42ba57d9230243
Autor:
Jishnu Das, Greg Delgoffe, Diwakar Davar, Stacy Wendell, Hector Nieves-Rosado, Bingxian Xie, Kristin Morder, Abigail E Overacre-Delgoffe, Drew Wilfahrt, Douglas Prado, Madison Nguyen, William Hawse, Larry Kane
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/be8d9a0267ee49a1ac5247c566d6bffb
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/50a83d2dd0414b5ba2afdd662c84d583
Publikováno v:
Mucosal Immunol
Resident memory T cells (Trms) predominantly reside within tissue and are critical for providing rapid protection against invasive viruses, fungi and bacteria. Given that tissues are heavily impacted and shaped by the microbiota, it stands to reason
Autor:
Timothy W. Hand, Ashley V. Menk, Lauren Mullinax, Kadir Ozler, Pailin Chiaranunt, Amanda C. Poholek, Natalie Rittenhouse, Brian Yueh, Ana S. H. Costa, Ansen H.P. Burr, Greg M. Delgoffe, Vaughn S. Cooper, Christopher W. Marshall, Junyi Ji, Abigail E. Overacre-Delgoffe, Onur Eskiocak, Semir Beyaz
The colonic epithelium requires continuous renewal by intestinal stem cells (ISCs) to restore the barrier after damage and proliferation of epithelial cells is modulated by dietary metabolites. We demonstrate that mice fed a high sugar diet failed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0f5223ea775e14ad2a33680603ccba4
https://doi.org/10.1101/2021.08.18.456840
https://doi.org/10.1101/2021.08.18.456840
Autor:
Timothy W. Hand, Tullia C. Bruno, Ansen H.P. Burr, Abigail E. Overacre-Delgoffe, Anthony R. Cillo, Hannah Bumgarner, Amrita Bhattacharjee, Justin T. Tometich, Dario A. A. Vignali
SummaryColorectal cancer (CRC) is a common and deadly disease, and patients with metastatic tumors often fail to respond to therapy. While select members of the microbiome are associated with improved anti-tumor immunity, mechanistic understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b86c947a68d46d6dfd38885366f2036d
https://doi.org/10.1101/2021.01.27.428417
https://doi.org/10.1101/2021.01.27.428417
Autor:
Ashley V. Menk, Natalie Rittenhouse, Brett M. Morrison, Stacy G. Wendell, Ronal Peralta, Timothy W. Hand, Steven J. Mullet, Paolo Vignali, Ryan D. Whetstone, Greg M. Delgoffe, Amanda C. Poholek, Kristin DePeaux, Stephanie Grebinoski, McLane Watson, Abigail E. Overacre-Delgoffe, Jeffrey D. Rothstein, Dario A. A. Vignali
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Regulatory T (Treg) cells are vital for preventing autoimmunity but are a major barrier to robust cancer immunity as the tumor microenvironment (TME) recruits and promotes their function. The deregulated cellular metabolism of tumor cells
Autor:
Amrita Bhattacharjee, Tullia C. Bruno, Justin T. Tometich, Abigail E. Overacre-Delgoffe, Timothy W. Hand, Anthony R. Cillo, Hannah Bumgarner, Dario A. A. Vignali, Ansen H.P. Burr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Colorectal cancer remains one of the most common and deadliest cancers worldwide and effective therapies are lacking. While immunotherapy has revolutionized treatment for many cancers, the overwhelming majority of colorectal cancer patient
Autor:
Elizabeth B. Norton, Amrita Bhattacharjee, Denise Morais da Fonseca, Yasmine Belkaid, Sean P. Spencer, Oliver J. Harrison, Abigail E. Overacre-Delgoffe, Justin T. Tometich, Ansen H.P. Burr, Timothy W. Hand, Jason A. Hall, Deyi Yang, Brydie R. Huckestein, Jonathan L. Linehan
SummaryEnvironmental Enteric Dysfunction (EED) is an intestinal disease caused by malnutrition and infection that leads to malabsorption and stunting. EED is also associated with a reduced efficacy of oral vaccines. We show in a microbiota and diet-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::178b4956afd467f519303ac1c36fb567
https://doi.org/10.1101/2020.06.03.130831
https://doi.org/10.1101/2020.06.03.130831
Autor:
Brydie R. Huckestein, Oliver J. Harrison, Deyi Yang, Ansen H.P. Burr, Justin T. Tometich, Jason A. Hall, Sean P. Spencer, Elizabeth B. Norton, Jonathan L. Linehan, Yasmine Belkaid, Amrita Bhattacharjee, Denise Morais da Fonseca, Abigail E. Overacre-Delgoffe, Timothy W. Hand
Publikováno v:
Immunity
Summary Environmental enteric dysfunction (EED) is a gastrointestinal inflammatory disease caused by malnutrition and chronic infection. EED is associated with stunting in children and reduced efficacy of oral vaccines. To study the mechanisms of ora