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of 7
pro vyhledávání: '"Abigail D. Bellis"'
Autor:
Michael S Weiss, Beatriz Peñalver Bernabé, Abigail D Bellis, Linda J Broadbelt, Jacqueline S Jeruss, Lonnie D Shea
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14026 (2010)
Extracellular activation of signal transduction pathways and their downstream target transcription factors (TFs) are critical regulators of cellular processes and tissue development. The intracellular signaling network is complex, and techniques that
Externí odkaz:
https://doaj.org/article/5c9e36bd41ed4331b62c96938779860c
Autor:
Seungjin Shin, Jacqueline S. Jeruss, D. Bluver, Szilard Asztalos, Julio Saez-Rodriguez, Abigail D. Bellis, Michael S. Weiss, B. Peñalver Bernabé, Debra A. Tonetti, M. D. Mui, S. J. Dubbury, Lonnie D. Shea, Linda J. Broadbelt
Publikováno v:
Integr. Biol.. 6:1170-1182
Tissue development and disease progression are multi-stage processes controlled by an evolving set of key regulatory factors, and identifying these factors necessitates a dynamic analysis spanning relevant time scales. Current omics approaches depend
Autor:
Seungjin Shin, Abigail D. Bellis, Lonnie D. Shea, Stanley Weng, Beatriz Penalver Bernabe, Michael S. Weiss, Linda J. Broadbelt
Publikováno v:
Biotechnology and Bioengineering. 110:563-572
Live-cell assays to measure cellular function performed within 3D cultures have the potential to elucidate the underlying processes behind disease progression and tissue formation. Cells cultured in 3D interact and remodel their microenvironment and
Autor:
Beatriz Peňalver-Bernabé, Linda J. Broadbelt, Abigail D. Bellis, Angela K. Pannier, Lonnie D. Shea, Jacqueline S. Jeruss, Michael E Yarrington, Michael S. Weiss, Maria V. Barbolina
Publikováno v:
Biotechnology and Bioengineering. 108:395-403
Identifying molecular mechanisms or therapeutic targets is typically based on large-scale cellular analysis that measures the abundance of mRNA or protein; however, abundance does not necessarily correlate with activity. We report a method for direct
Autor:
Zain Bengali, Eric A. Ariazi, Abigail D. Bellis, V. Craig Jordan, Lonnie D. Shea, Angela K. Pannier
Publikováno v:
Biotechnology and Bioengineering. 98:486-497
Transfected cell arrays (TCAs) represent a high-throughput technique to correlate gene expression with functional cell responses. Despite advances in TCAs, improvements are needed for the widespread application of this technology. We have developed a
Autor:
Beatriz Penalver Bernabe, Abigail D. Bellis, Lonnie D. Shea, Michael S. Weiss, Linda J. Broadbelt, Jacqueline S. Jeruss
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e14026 (2010)
PLoS ONE, Vol 5, Iss 11, p e14026 (2010)
Background Extracellular activation of signal transduction pathways and their downstream target transcription factors (TFs) are critical regulators of cellular processes and tissue development. The intracellular signaling network is complex, and tech
Autor:
Theresa R. Cassino, Anne S. Robinson, Kimberly Forsten-Williams, Abigail D. Bellis, Thomas E. Ryan, Laura J. Delo
Publikováno v:
Journal of cellular physiology. 210(2)
The cellular microenvironment impacts how signals are transduced by cells and plays a key role in tissue homeostasis. Although pH is generally well regulated, there are a number of situations where acidosis occurs and our work addresses how low pH im