Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Abigail B. Bernard"'
Autor:
Kristi S. Anseth, Abigail B. Bernard, Thomas Hraha, Kelly M. T. Shekiro, Richard K.P. Benninger
A major limitation of islet transplantation as a therapy for treating Type 1 Diabetes is eventual graft failure, which can be partially attributed to islet cell death. When cultured in vitro, cells in the center of large islets show increased necrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be428cc49a329cb15811ce1f250dce70
https://doi.org/10.1101/2020.02.07.939538
https://doi.org/10.1101/2020.02.07.939538
Publikováno v:
Biotechnology and Bioengineering. 111:1028-1037
Multi-cellular aggregates are found in healthy and diseased tissues, and while cell–cell contact is important for regulating many cell functions, cells also interact, to varying degrees, with extra-cellular matrix (ECM) proteins. Islets of Langerha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b2e32398cff0a639ffd2af1d730a74
https://doi.org/10.1002/bit.25153
https://doi.org/10.1002/bit.25153
Publikováno v:
Biophysical journal. 106(1)
Pancreatic islets of Langerhans regulate blood glucose homeostasis by the secretion of the hormone insulin. Like many neuroendocrine cells, the coupling between insulin-secreting β-cells in the islet is critical for the dynamics of hormone secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c047414dad4925884fe979b367c1eba
https://pubmed.ncbi.nlm.nih.gov/24411262
https://pubmed.ncbi.nlm.nih.gov/24411262
Cell-cell contact between pancreatic β-cells is important for maintaining survival and normal insulin secretion. Various techniques have been developed to promote cell-cell contact between β-cells, but a simple yet robust method that affords precis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dde34e54f806b58e60eb4b8ea564c05
https://europepmc.org/articles/PMC3401388/
https://europepmc.org/articles/PMC3401388/
Publikováno v:
Biophysical Journal. 104:491a-492a
The pancreatic islet is a multicellular organ which provides the sole source of insulin for regulating blood glucose levels. Thus, a functional understanding of the islet is of critical importance to effectively treat diabetes. Beta cells within nati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc0881b58c623c484eb9f4be6966a63
https://doi.org/10.1016/j.bpj.2012.11.2710
https://doi.org/10.1016/j.bpj.2012.11.2710