Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Abigail A. Jaquish"'
Autor:
Won Jong Jin, Amy K. Erbe, Ciara N. Schwarz, Abigail A. Jaquish, Bryce R. Anderson, Raghava N. Sriramaneni, Justin C. Jagodinsky, Amber M. Bates, Paul A. Clark, Trang Le, Keng-Hsueh Lan, Yi Chen, KyungMann Kim, Zachary S. Morris
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In head and neck squamous cell carcinoma (HNSCC) tumors that over-expresses huEGFR, the anti-EGFR antibody, cetuximab, antagonizes tumor cell viability and sensitizes to radiation therapy. However, the immunologic interactions between cetuximab and r
Externí odkaz:
https://doaj.org/article/cb1c402282874fdc932a12949b4cd965
Autor:
Zachary S Morris, Jasdeep Kler, Kyung Mann Kim, Emily I Guy, Paul A Clark, Raghava N Sriramaneni, Won Jong Jin, Justin C Jagodinsky, Amber M Bates, Abigail A Jaquish, Bryce R Anderson, Trang Le, Jonathan A Lubin, Ishan Chakravarty, Ian S Arthur, Clinton M Heinze, Kelsey A Klar, Peter M Carlson, John S Kuo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immune checkpoint inhibition (ICI) alone is not efficacious for a large number of patients with melanoma brain metastases. We previously established an in situ vaccination (ISV) regimen combining radiation and immunocytokine to enhance res
Externí odkaz:
https://doaj.org/article/5403053984ba479cad7610cc87ac2b46
Autor:
Paul M. Sondel, Paul M. Harari, Alexander L. Rakhmilevich, Jacquelyn A. Hank, Amy K. Erbe, Alan J. Korman, Stephen D. Gillies, Hans Loibner, Lakeesha L. Carmichael, Raghava N. Sriramaneni, Abigail A. Jaquish, Sara M. Busche, Jasdeep S. Kler, Clinton M. Heinze, Peter M. Carlson, Lauryn R. Werner, Emily I. Guy, Zachary S. Morris
Concomitant immune tolerance prevents an immunotherapeutic response at the distant tumor site, is observed with an 8 Gy x 3 fraction RT regimen, and requires a well-established macroscopic secondary tumor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92254349c1fed9f2a810f37376c5a2d7
https://doi.org/10.1158/2326-6066.22539017.v1
https://doi.org/10.1158/2326-6066.22539017.v1
Autor:
Paul M. Sondel, Paul M. Harari, Alexander L. Rakhmilevich, Jacquelyn A. Hank, Amy K. Erbe, Alan J. Korman, Stephen D. Gillies, Hans Loibner, Lakeesha L. Carmichael, Raghava N. Sriramaneni, Abigail A. Jaquish, Sara M. Busche, Jasdeep S. Kler, Clinton M. Heinze, Peter M. Carlson, Lauryn R. Werner, Emily I. Guy, Zachary S. Morris
In situ vaccination is an emerging cancer treatment strategy that uses local therapies to stimulate a systemic antitumor immune response. We previously reported an in situ vaccination effect when combining radiation (RT) with intratumor (IT) injectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e318cbf624cef92a30ae9c67df48f38
https://doi.org/10.1158/2326-6066.c.6548969
https://doi.org/10.1158/2326-6066.c.6548969
Autor:
Paul M. Sondel, Paul M. Harari, Alexander L. Rakhmilevich, Jacquelyn A. Hank, Amy K. Erbe, Alan J. Korman, Stephen D. Gillies, Hans Loibner, Lakeesha L. Carmichael, Raghava N. Sriramaneni, Abigail A. Jaquish, Sara M. Busche, Jasdeep S. Kler, Clinton M. Heinze, Peter M. Carlson, Lauryn R. Werner, Emily I. Guy, Zachary S. Morris
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e0aef92280465dad14cf60df132bde
https://doi.org/10.1158/2326-6066.22539008.v1
https://doi.org/10.1158/2326-6066.22539008.v1
Autor:
Lauren C. Smith, Xin Sun, Yujuan Su, Mike Klodnicki, Marsida Kallupi, Sharona Sedighim, Nathan Velarde, Kokila Shankar, Lani Tieu, Jamie Barr, Abigail A Jaquish, Giordano de Guglielmo, Olivier George, Lieselot L. G. Carrette
Publikováno v:
Neuropsychopharmacology
The debate about electronic cigarettes is dividing healthcare professionals, policymakers, manufacturers, and communities. A key limitation in our understanding of the cause and consequences of vaping is the lack of animal models of nicotine vapor se
Autor:
Zachary S. Morris, Amber M. Bates, Justin C. Jagodinsky, Won Jong Jin, Bryce R. Anderson, Ciara N. Schwarz, Abigail A Jaquish, Raghava N. Sriramaneni, Yi Chen, Keng-Hsueh Lan, Trang T. Le, KyungMann Kim, Amy K. Erbe, Paul A. Clark
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
In head and neck squamous cell carcinoma (HNSCC) tumors that over-expresses huEGFR, the anti-EGFR antibody, cetuximab, antagonizes tumor cell viability and sensitizes to radiation therapy. However, the immunologic interactions between cetuximab and r
Autor:
Alan J. Korman, Jacquelyn A. Hank, Zachary S. Morris, Stephen D. Gillies, Paul M. Harari, Hans Loibner, Sara M. Busche, Emily I. Guy, Alexander L. Rakhmilevich, Lakeesha Carmichael, Lauryn R. Werner, Paul M. Sondel, Abigail A Jaquish, Raghava N. Sriramaneni, Jasdeep S. Kler, Amy K. Erbe, Clinton M. Heinze, Peter M. Carlson
Publikováno v:
Cancer Immunology Research. 6:825-834
In situ vaccination is an emerging cancer treatment strategy that uses local therapies to stimulate a systemic antitumor immune response. We previously reported an in situ vaccination effect when combining radiation (RT) with intratumor (IT) injectio
Autor:
Paul A. Clark, Abigail A Jaquish, Zachary S. Morris, Wonjong Jin, Amy K. Erbe, Justin C. Jagodinsky, Ciara N. Schwarz, Bryce R. Anderson, Raghava N. Sriramaneni
Publikováno v:
Cancer Research. 80:1881-1881
Purpose: Patients with head and neck squamous cell carcinoma (HNSCC) treated with anti-EGFR (cetuximab) mAb-based immunotherapy often acquire therapy-resistance, reducing clinical benefit. We evaluated the efficacy of a combined modality in situ vacc
Autor:
Zachary S, Morris, Emily I, Guy, Lauryn R, Werner, Peter M, Carlson, Clinton M, Heinze, Jasdeep S, Kler, Sara M, Busche, Abigail A, Jaquish, Raghava N, Sriramaneni, Lakeesha L, Carmichael, Hans, Loibner, Stephen D, Gillies, Alan J, Korman, Amy K, Erbe, Jacquelyn A, Hank, Alexander L, Rakhmilevich, Paul M, Harari, Paul M, Sondel
Publikováno v:
Cancer immunology research. 6(7)
In situ vaccination is an emerging cancer treatment strategy that uses local therapies to stimulate a systemic antitumor immune response. We previously reported an in situ vaccination effect when combining radiation (RT) with intra-tumor (IT) injecti