Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Abie Craiu"'
Autor:
Kristin Beaudry, Keith A. Reimann, Abie Craiu, Tavis D. Steenbeke, Michelle A. Lifton, Dan H. Barouch, Julie D. Frost, Norman L. Letvin, Marcelo J. Kuroda, Terry B. Strom, Christy E. Nickerson, Joern E. Schmitz, Xin Xiao Zheng
Publikováno v:
AIDS Research and Human Retroviruses. 17:873-886
The T cell-stimulatory cytokine interleukin 2 (IL-2) is being evaluated as a therapeutic in the clinical settings of HIV infection and cancer. However, the clinical utility of IL-2 may be mitigated by its short in vivo half-life, toxic effects, and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e6b6f58defbcb0ca5768bffcf3c9a1
https://doi.org/10.1089/088922201750290005
https://doi.org/10.1089/088922201750290005
Autor:
Mark G. Lewis, Michael A. Egan, Vanessa M. Hirsch, Linda S. Wyatt, Jae-Hwan Nam, Georgia R. Krivulka, Sampa Santra, Norman L. Letvin, Marcelo J. Kuroda, Bernard Moss, Christine E. Nickerson, Dan H. Barouch, Tong-Ming Fu, Michelle A. Lifton, John W. Shiver, Abie Craiu, Jörn E. Schmitz, Carol I. Lord
Publikováno v:
Journal of Virology. 75:2462-2467
Increasing evidence suggests that the generation of cytotoxic T-lymphocyte (CTL) responses specific for a diversity of viral epitopes will be needed for an effective human immunodeficiency virus type 1 (HIV-1) vaccine. Here, we determine the frequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5950f8fa3c12dc16ad0f018e0d476d75
https://doi.org/10.1128/jvi.75.5.2462-2467.2001
https://doi.org/10.1128/jvi.75.5.2462-2467.2001
Publikováno v:
The Journal of Immunology. 164:4003-4010
The proteasome has been shown to make the proper C-terminal cleavage for the generation of several immunodominant class I-presented peptides whereas aminopeptidases generate their proper N termini. In this study, we show that these two distinct prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74e9ec3cb390cf79e7f14393f017192
https://doi.org/10.4049/jimmunol.164.8.4003
https://doi.org/10.4049/jimmunol.164.8.4003
Autor:
Terry B. Strom, Gwendolyn J. Heidecker, John W. Shiver, Christine E. Nickerson, Helen C. Perry, Sampa Santra, Hong Xie, Michelle A. Lifton, Xin Xiao Zheng, Carroll L. Crabbs, Dan H. Barouch, Georgia R. Krivulka, Carol I. Lord, Tavis D. Steenbeke, Julie D. Frost, David C. Montefiori, Marcelo J. Kuroda, Mary-Ellen Davies, Mark G. Lewis, Abie Craiu, Jörn E. Schmitz, Norman L. Letvin
Publikováno v:
Proceedings of the National Academy of Sciences. 97:4192-4197
The potential utility of plasmid DNA as an HIV-1 vaccination modality currently is an area of active investigation. However, recent studies have raised doubts as to whether plasmid DNA alone will elicit immune responses of sufficient magnitude to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d37aeccf743bbcf9c7bb22ec45819f7
https://doi.org/10.1073/pnas.050417697
https://doi.org/10.1073/pnas.050417697
Autor:
Dan H. Barouch, Sampa Santra, Tavis D. Steenbeke, Xin X. Zheng, Helen C. Perry, Mary-Ellen Davies, Daniel C. Freed, Abie Craiu, Terry B. Strom, John W. Shiver, Norman L. Letvin
Publikováno v:
The Journal of Immunology. 161:1875-1882
The use of cytokines has shown promise as an approach for amplifying vaccine-elicited immune responses, but the application of these immunomodulatory molecules in this setting has not been systematically explored. In this report we investigate the us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9f3341288f5aed57eff6a1d312592e
https://doi.org/10.4049/jimmunol.161.4.1875
https://doi.org/10.4049/jimmunol.161.4.1875
Publikováno v:
Proceedings of the National Academy of Sciences. 94:10850-10855
Although cellular proteins degraded by proteasomes are the source of most antigenic peptides presented on major histocompatibility complex class I molecules, it is unknown whether the eight- to nine-residue peptides that fit in the binding groove of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684ed54bcd8226fe0fb9fe43ff54ff8d
https://doi.org/10.1073/pnas.94.20.10850
https://doi.org/10.1073/pnas.94.20.10850
Autor:
Abie Craiu, Alfred L. Goldberg, Tatos Akopian, Maria Gaczynska, Kenneth L. Rock, Gabriel Fenteany, Colette F. Gramm
Publikováno v:
Journal of Biological Chemistry. 272:13437-13445
The antibiotic lactacystin was reported to covalently modify beta-subunit X of the mammalian 20 S proteasome and inhibit several of its peptidase activities. However, we demonstrate that [3H]lactacystin treatment modifies all the proteasome's catalyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3362e10cd4be68bd5ba5b6fff2956037
https://doi.org/10.1074/jbc.272.20.13437
https://doi.org/10.1074/jbc.272.20.13437
Autor:
Abie, Craiu, David, Scadden
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 423
Electroporation has been used in biological laboratories for many years to transiently porate cell membranes and permit plasmid or protein transfection. It has been shown that the application of pulsed electric fields (PEFs) of defined strength will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a027f11522dcc3a0a866bf20f47ca84
https://pubmed.ncbi.nlm.nih.gov/18370208
https://pubmed.ncbi.nlm.nih.gov/18370208
Autor:
David T. Scadden, Abie Craiu
Publikováno v:
Methods in Molecular Biology ISBN: 9781588298775
Electroporation has been used in biological laboratories for many years to transiently porate cell membranes and permit plasmid or protein transfection. It has been shown that the application of pulsed electric fields (PEFs) of defined strength will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8be0c89f2adb94810dc978484e9dba91
https://doi.org/10.1007/978-1-59745-194-9_22
https://doi.org/10.1007/978-1-59745-194-9_22
Autor:
Ana Limón, Neil P. Rodrigues, Abie Craiu, Paul G. Richardson, Joseph A. Mangano, Henry M. Eppich, Rebecca Rich, Eyal C. Attar, Peter S. Choi, Kenneth C. Anderson, David T. Scadden, Paula G. O'Connor, Douglas P. Olson, David Dombkowski, John G. Gribben, Kenneth S. Cohen, Gregor B. Adams, Yoriko Saito, Jonathan Grogins, Jay Freshman, Robert L. Schlossman
Publikováno v:
Blood. 105(5)
Autologous stem cell transplantation, in the setting of hematologic malignancies such as lymphoma, improves disease-free survival if the graft has undergone tumor purging. Here we show that flowing hematopoietic cells through pulsed electric fields (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e49712f362181dce6f97522dc15f76
https://pubmed.ncbi.nlm.nih.gov/15292069
https://pubmed.ncbi.nlm.nih.gov/15292069