Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Abi S. Witherden"'
Autor:
Helmut Fuchs, Rainer Klocke, Martin Hrabé de Angelis, Holger Hummerich, Christiana Ruhrberg, Gabriele Stumm, Sharon E. Nicholson, Martina Rudelius, Florian Boehme, Martin Augustin, Andreas Popp, P. Jeffrey Morgan, Azlina Ahmad-Annuar, Andreas Russ, Juergen Schlegel, Giampietro Schiavo, Takashi Toda, Elizabeth M. C. Fisher, Andreas Marquardt, Ayumu Yamamoto, Yasushi Hiraoka, John V. Priestley, Simon T. Ball, Giovanna Lalli, Sigrid Wattler, Samantha Bowen, Sharon Averill, Ravi Oozageer, Abi S. Witherden, Stefan Lampel, Joanne E. Martin, V.R. King, David T. Shima, Gisela Peraus, Majid Hafezparast, Dirk Korthaus, Philipp Wabnitz, Jo Peters, Carmen Dickneite
Publikováno v:
Science. 300:808-812
Degenerative disorders of motor neurons include a range of progressive fatal diseases such as amyotrophic lateral sclerosis (ALS), spinal-bulbar muscular atrophy (SBMA), and spinal muscular atrophy (SMA). Although the causative genetic alterations ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc1b849b21ad04d5cb8b776bad98504
https://doi.org/10.1126/science.1083129
https://doi.org/10.1126/science.1083129
Autor:
Josephine Peters, Joanne E. Martin, Abi S. Witherden, E. M. C. Fisher, Nessan Bermingham, J. Mackin, Sharon J. Nicholson, Simon T. Ball, Majid Hafezparast, Frank Baas, A. L. M. A. ten Asbroek
Publikováno v:
Neuroscience letters, 273(1), 49-52. Elsevier Ireland Ltd
The underlying genetic cause is known for only 10-20% of familial motor neuron disease (MND). Thus the genes involved in the aetiology of 80-90% of familial MND remain to be determined, and animal models are powerful tools for undertaking this task.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8702bcd8a827c2cace312cb13883df01
https://doi.org/10.1016/s0304-3940(99)00620-5
https://doi.org/10.1016/s0304-3940(99)00620-5
Autor:
Paresh Shah, Pamela J. Shaw, Holger Hummerich, J. Kirby, Majid Hafezparast, Andrew H. Crosby, Azlina Ahmad-Annuar, Karen E. Morrison, Philip A. Wilkinson, LJ Bradley, Abi S. Witherden, Thomas T. Warner, Elizabeth M. C. Fisher, Christos Proukakis, Richard W. Orrell, Joanne E. Martin
Publikováno v:
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases. 4(3)
We have shown in a mouse model of motor neuron disease, the legs-at-odd-angles (Loa) mutant, and that mutations in the cytoplasmic dynein heavy chain gene (Dnchc1) cause motor neuron degeneration. Mice exhibiting the Loa phenotype suffer progressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4147421088b6c11d1dd36106405b66ee
https://pubmed.ncbi.nlm.nih.gov/13129801
https://pubmed.ncbi.nlm.nih.gov/13129801
Autor:
Joanna Rankin, Elizabeth M. C. Fisher, Abi S. Witherden, Azlina Ahmad-Annuar, Holger Hummerich, Simon T. Ball, Sharon J. Nicholson, Nessan Bermingham, Derek Huntley, Joanne E. Martin, Majid Hafezparast, Marek Sergot, Demet Araç, Jo Peters, Marjan Iravani
Publikováno v:
Gene. 283(1-2)
A variety of loci with interesting patterns of regulation such as imprinted expression, and critical functions such as involvement in tumour necrosis factor pathways, map to a distal portion of mouse chromosome 12. This region also contains disease r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4e6f04b38af1bfb9bf8ad5c474da96
https://pubmed.ncbi.nlm.nih.gov/11867214
https://pubmed.ncbi.nlm.nih.gov/11867214
Autor:
Derek C. Rogers, Majid Hafezparast, Elizabeth M. C. Fisher, Jo Peters, Sharon J. Nicholson, Tracey L. Robinson, Abi S. Witherden, Judy Latcham, Charlotte A. Quilter, Joanne E. Martin, Simon T. Ball
Publikováno v:
Neuroscience letters. 306(1-2)
Mouse models of neurological abnormalities are only valuable if accurately assessed. The three-stage SHIRPA procedure is used for the standardised assessment of mouse phenotype and has been reported in a high throughput experiment in which different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d45a62c73cab6c36959ac2788d5866
https://pubmed.ncbi.nlm.nih.gov/11403965
https://pubmed.ncbi.nlm.nih.gov/11403965
Autor:
Joanne E. Martin, Abi S. Witherden, Elizabeth M. C. Fisher, Sharon J. Nicholson, Majid Hafezparast
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 11(12)
Motor neurons are among some of the most unusual cells in the body becaue of their immense size and their role as the critical link between the motor centers of the brain and the muscles. In addition to their intrinsic biological interest, it is vita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97065a3c54340afa870d24935db35a63
https://pubmed.ncbi.nlm.nih.gov/11130970
https://pubmed.ncbi.nlm.nih.gov/11130970
Autor:
Amy L. Roberts, Timothy J. Vyse, John C. Whittaker, Timothy J. Aitman, David L. Morris, Abi S. Witherden
Publikováno v:
Clinical Immunology. 131:S101-S102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490bfe3e89f178c5fa86e47d74581b0c
https://doi.org/10.1016/j.clim.2009.03.295
https://doi.org/10.1016/j.clim.2009.03.295
Autor:
Patti A. Quant, David Saggerson, Elizabeth M. C. Fisher, Sharon J. Nicholson, Josephine Peters, Carole D. Nickols, Mahmoud Naase, N. M. Broadway, Abi S. Witherden, Joanne E. Martin, Demet Araç, Carol Lascelles, Majid Hafezparast, Edwin Cooper, C S Baker, Simon T. Ball, Stephen Gokhale
Publikováno v:
Scopus-Elsevier
Low blood sugar levels are a well-known cause of severe illness and often death in newborn humans, especially those that are small for age. Few of the causes of neonatal hypoglycemia are known, and many remain to be found. We describe a novel mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ccabccc25cc3037025569fdad54460
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036017942&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036017942&partnerID=MN8TOARS
