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Autor:
Ganesh, Suhas, Ashok, Abhishekh Hulegar, Kumar, Chennaveerachari Naveen, Thirthalli, Jagadish
Publikováno v:
In Asian Journal of Psychiatry August 2016 22:86-92
Autor:
Chandran, Sajish, Abhishekh, Hulegar A., Murthy, Pratima, Raju, Trichur R., Sathyaprabha, Talakad N.
Publikováno v:
In Asian Journal of Psychiatry October 2015 17:61-64
Autor:
Kishore, Ramakrishna K., Abhishekh, Hulegar A., Udupa, Kaviraja, Thirthalli, Jagadisha, Lavekar, Gandhidas S., Gangadhar, Bangalore N., Raju, Trichur R., Sathyaprabha, Talakad N.
Publikováno v:
In Asian Journal of Psychiatry December 2014 12:100-107
Autor:
Jan Passchier, Eugenii A. Rabiner, Roger N. Gunn, Anne Lingford-Hughes, David J. Nutt, Alessandro Colasanti, Abhishekh Hulegar Ashok, Tiago Reis Marques, Samuel Turton, Oliver D. Howes, Jim Myers, Gary Frost
Publikováno v:
Journal of Psychopharmacology (Oxford, England)
Funder: Medical Research Council; FundRef: https://doi.org/10.13039/501100000265
INTRODUCTION: A recent study has shown that acetate administration leads to a fourfold increase in the transcription of proopiomelanocortin (POMC) mRNA in the hypot
INTRODUCTION: A recent study has shown that acetate administration leads to a fourfold increase in the transcription of proopiomelanocortin (POMC) mRNA in the hypot
Autor:
Abhishekh, Hulegar A., Thirthalli, Jagadisha, Manjegowda, Anusha, Phutane, Vivek H., Muralidharan, Kesavan, Gangadhar, Bangalore N.
Publikováno v:
In Psychiatry Research 30 September 2013 209(2):155-159
Autor:
Ilinca Angelescu, Oliver D. Howes, Federico Turkheimer, Anne Lingford-Hughes, Jim Myers, Tiago Reis Marques, David J. Nutt, Faith Borgan, Mattia Veronese, Abhishekh Hulegar Ashok
Publikováno v:
Reis Marques, T, Borgan, F, Ashok, A H, Ureche-Angelescu, I, Meyers, J, Lingford-Hughes, A, Nutt, D, Veronese, M, Turkheimer, F E & Howes, O 2020, ' GABA-A receptor differences in Schizophrenia : A Positron Emission Tomography study using [11C]Ro154513 ', Molecular Psychiatry, vol. 0, no. 0, pp. 1-10 . https://doi.org/10.1038/s41380-020-0711-y
A loss of GABA signaling is a prevailing hypothesis for the pathogenesis of schizophrenia. Preclinical studies indicate that blockade of the α5 subtype of the GABA receptor (α5-GABAARs) leads to behavioral phenotypes associated with schizophrenia,
Autor:
David J. Nutt, E.A. Rabiner, Yvonne Lewis, Mickael Huiban, David Erritzoe, Azeem Saleem, Sara Moz, Alessandro Colasanti, John Beaver, Graham E. Searle, Gitte M. Knudsen, Anne Lingford-Hughes, Oliver D. Howes, Samuel Turton, Jan Passchier, Roger N. Gunn, Abhishekh Hulegar Ashok
Publikováno v:
Neuropsychopharmacology. 45:804-810
Positron emission tomography (PET) enables non-invasive estimation of neurotransmitter fluctuations in the living human brain. While these methods have been applied to dopamine and some other transmitters, estimation of 5-hydroxytryptamine (5-HT; Ser
Autor:
Iris E. C. Sommer, Paola Dazzan, Tiago Reis Marques, Oliver D. Howes, Abhishekh Hulegar Ashok, Federico Turkheimer, Toby Pillinger, Mattia Veronese
Publikováno v:
Psychological Medicine
Psychological Medicine, 49(13), 2186-2196. Cambridge University Press
Reis Marques, T, Ashok, A H, Pillinger, T, Veronese, M, Turkheimer, F E, Dazzan, P, Sommer, I E C & Howes, O D 2018, ' Neuroinflammation in schizophrenia : meta-analysis of in-vivo microglial imaging studies ', Psychological Medicine . https://doi.org/10.1017/S0033291718003057
Psychological Medicine, 49(13), 2186-2196. Cambridge University Press
Reis Marques, T, Ashok, A H, Pillinger, T, Veronese, M, Turkheimer, F E, Dazzan, P, Sommer, I E C & Howes, O D 2018, ' Neuroinflammation in schizophrenia : meta-analysis of in-vivo microglial imaging studies ', Psychological Medicine . https://doi.org/10.1017/S0033291718003057
BackgroundConverging lines of evidence implicate an important role for the immune system in schizophrenia. Microglia are the resident immune cells of the central nervous system and have many functions including neuroinflammation, axonal guidance and