Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Abhishek, Trigunaite"'
Autor:
Daniel Tusé, Micaela Reeves, Joshua Royal, Krystal T. Hamorsky, Hanna Ng, Maria Arolfo, Carol Green, Abhishek Trigunaite, Toufan Parman, Goo Lee, Nobuyuki Matoba
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 380:162-170
The novel wound-healing biologic EPICERTIN, a recombinant analog of cholera toxin B subunit, is in early development for the management of ulcerative colitis. This study established for the first time the pharmacokinetics (PK), bioavailability (BA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2325760699d38df82660b89afa3917b1
https://doi.org/10.1124/jpet.121.000904
https://doi.org/10.1124/jpet.121.000904
Autor:
Philip H. Iffland, II, Juliana Carvalho-Tavares, Abhishek Trigunaite, Shumei Man, Peter Rasmussen, Andreas Alexopoulos, Chaitali Ghosh, Trine N. Jørgensen, Damir Janigro
Publikováno v:
Neurobiology of Disease, Vol 59, Iss , Pp 206-219 (2013)
There are overwhelming data supporting the inflammatory origin of some epilepsies (e.g., Rasmussen's encephalitis and limbic encephalitis). Inflammatory epilepsies with an autoimmune component are characterized by autoantibodies against membrane-boun
Externí odkaz:
https://doaj.org/article/fd5c14557a28417592ee7050befe1678
Autor:
Courtney Glavis-Bloom, Andrea J. Tenner, Joseph Rogers, Jenny U. Johansson, Abhishek Trigunaite, William D. Brubaker, Tanya L. Wallace, Andrés Crane, Justine Ceballos, Bonnie Bradt
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 14, iss 2
Introduction Our previous studies have shown that amyloid β peptide (Aβ) is subject to complement-mediated clearance from the peripheral circulation, and that this mechanism is deficient in Alzheimer's disease. The mechanism should be enhanced by A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f08925f579bc6249d9bae59a84e573
https://doi.org/10.1016/j.jalz.2017.04.015
https://doi.org/10.1016/j.jalz.2017.04.015
Publikováno v:
Cellular Immunology. 294:87-94
Sex-based disparities in immune responses are well known phenomena. The two most important factors accounting for the sex-bias in immunity are genetics and sex hormones. Effects of female sex hormones, estrogen and progesterone are well established,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb84d159fb81260f4c7ffc298856626
https://doi.org/10.1016/j.cellimm.2015.02.004
https://doi.org/10.1016/j.cellimm.2015.02.004
Publikováno v:
The Journal of Immunology. 192:1570-1576
Systemic lupus erythematosus is an autoimmune disease characterized by elevated production of autoreactive Abs. The disease has a much higher prevalence in women than in men. Although testosterone has been shown to be protective in the disease, and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190f2089b675ca5a1426995205cd6257
https://doi.org/10.4049/jimmunol.1302479
https://doi.org/10.4049/jimmunol.1302479
Autor:
Megan K. L. MacLeod, Angela C. Johnson, Philippa Marrack, Abhishek Trigunaite, Alexandria David, Trine N. Jørgensen
Publikováno v:
Genes and immunity
Most systemic autoimmune diseases occur more frequently in females than in males. This is particularly evident in Sjögren's syndrome, systemic lupus erythromatosis (SLE) and thyroid autoimmunity, where the ratio of females to males ranges from 20:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0e1ef58ae6bf31b997081e46bddeef
https://doi.org/10.1038/gene.2014.2
https://doi.org/10.1038/gene.2014.2
Gr-1highCD11b+ Cells Suppress B Cell Differentiation and Lupus-like Disease in Lupus-Prone Male Mice
Publikováno v:
Arthritis & Rheumatism. 65:2392-2402
Objective Systemic lupus erythematosus (SLE) develops much more readily in females than in males. Previous research has focused primarily on identifying mechanisms pertinent to the pathology in females. The aim of the current study was to delineate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8029112793b26b8977672c3e7c21376b
https://doi.org/10.1002/art.38048
https://doi.org/10.1002/art.38048
Publikováno v:
Journal of Clinical & Cellular Immunology.
A hallmark of SLE is the presence of elevated levels of circulating anti-nuclear autoantibodies specific towards chromatin, histones or dsDNA. Understanding the regulation of antibody production is therefore of utmost importance in understanding lupu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7922f9e2273f9b948eb3293533ebd372
https://doi.org/10.4172/2155-9899.1000239
https://doi.org/10.4172/2155-9899.1000239
Publikováno v:
The Journal of Immunology. 196:210.8-210.8
Systemic Lupus Erythematosus (SLE) is an autoimmune disease with high levels of autoreactive B cells and circulating anti-nuclear autoantibodies. Circulating antibody-antigen immune complexes deposit in tissues, including the kidney, causing chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2dca5ab173653b02a28b91611f5bda7
https://doi.org/10.4049/jimmunol.196.supp.210.8
https://doi.org/10.4049/jimmunol.196.supp.210.8
Autor:
Abhishek, Trigunaite, Ayesha, Khan, Evan, Der, Anne, Song, Sanjay, Varikuti, Trine N, Jørgensen
Publikováno v:
Arthritis and rheumatism. 65(9)
Systemic lupus erythematosus (SLE) develops much more readily in females than in males. Previous research has focused primarily on identifying mechanisms pertinent to the pathology in females. The aim of the current study was to delineate active prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39d707347504b50c807f38809c46d554
https://pubmed.ncbi.nlm.nih.gov/23797308
https://pubmed.ncbi.nlm.nih.gov/23797308