Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Abhirami P. Suresh"'
Autor:
Arezoo Esrafili, Abhirami Thumsi, Madhan Mohan Chandra Sekhar Jaggarapu, Richard G. Nile, Joshua Kupfer, Margaret Dugoni, Abhirami P. Suresh, Taravat Khodaei, Huikang Qian, Anna Mathis, Brandon Kim, Srivatsan J. Swaminathan, Wei Sun, Yeo Weon Seo, Kelly Lintecum, Sanmoy Pathak, Xinbo Tong, Julianne L. Holloway, Kailong Jin, Abhinav P. Acharya
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Biomaterials can act as pro- or anti-inflammatory agents. However, effects of biomaterials crystallinity on immune responses are poorly understood. We demonstrate that the adjuvant-like behaviour of covalent organic framework (COF) biomateri
Externí odkaz:
https://doaj.org/article/a48a41579cd841e285121b667e8756c6
Autor:
Sahil Inamdar, Abhirami P. Suresh, Joslyn L. Mangal, Nathan D. Ng, Alison Sundem, Christopher Wu, Kelly Lintecum, Abhirami Thumsi, Taravat Khodaei, Michelle Halim, Nicole Appel, Madhan Mohan Chandra Sekhar Jaggarapu, Arezoo Esrafili, Jordan R. Yaron, Marion Curtis, Abhinav P. Acharya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Inhibition of glycolysis in immune cells and cancer cells diminishes their activity, and thus combining immunotherapies with glycolytic inhibitors is challenging. Herein, a strategy is presented where glycolysis is inhibited in cancer cells
Externí odkaz:
https://doaj.org/article/1b742fa55db040f2888e0d48066e3a19
Publikováno v:
Bioactive Materials, Vol 24, Iss , Pp 153-170 (2023)
Alloy based implants have made a great impact in the clinic and in preclinical research. Immune responses are one of the major causes of failure of these implants in the clinic. Although the immune responses toward non-degradable alloy implants are w
Externí odkaz:
https://doaj.org/article/dfb7421dd7d24a91b48a5f66368c2b3e
Autor:
Sahil Inamdar, Abhirami P. Suresh, Joslyn L. Mangal, Nathan D. Ng, Alison Sundem, Hoda Shokrollahzadeh Behbahani, Thomas E. Rubino, Xiaojian Shi, Sharon T. Loa, Jordan R. Yaron, Taro Hitosugi, Matthew Green, Haiwei Gu, Marion Curtis, Abhinav P. Acharya
Publikováno v:
Journal of Controlled Release. 358:541-554
Autor:
Abhirami Thumsi, Srivatsan J. Swaminathan, Joslyn L. Mangal, Abhirami P. Suresh, Abhinav P. Acharya
Publikováno v:
Drug Delivery and Translational Research.
Autor:
Joslyn L. Mangal, Sahil Inamdar, Abhirami P. Suresh, Madhan Mohan Chandra Sekhar Jaggarapu, Arezoo Esrafili, Nathan D. Ng, Abhinav P. Acharya
Publikováno v:
Biomaterials Science. 10:6688-6697
Activated effector T cells induce pro-inflammatory responses in rheumatoid arthritis (RA) which then lead to inflammation of the joints. In this report, we demonstrate that polymeric nanoparticles with alpha keto-glutarate (aKG) in their polymer back
Autor:
Sahil Inamdar, Tina Tylek, Abhirami Thumsi, Abhirami P. Suresh, Madhan Mohan Chandra Sekhar Jaggarapu, Michelle Halim, Shivani Mantri, Arezoo Esrafili, Nathan D. Ng, Elizabeth Schmitzer, Kelly Lintecum, Camila de Ávila, John D. Fryer, Ying Xu, Kara L. Spiller, Abhinav P. Acharya
Publikováno v:
Biomaterials. 293:121973
Although different metabolic pathways have been associated with distinct macrophage phenotypes, the field of utilizing metabolites to modulate macrophage phenotype is in a nascent stage. In this report, we developed microparticles based on polymeriza
Publikováno v:
Advanced drug delivery reviews. 184
Drug delivery vehicles have made a great impact on cancer immunotherapies in clinics and pre-clinical research. Notably, the science of delivery of cancer vaccines and immunotherapeutics, modulating immune cell functions has inspired development of s