Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Abhimanyu K Singh"'
Autor:
Abhimanyu K Singh, M Álvaro Berbís, Mónika Z Ballmann, Michelle Kilcoyne, Margarita Menéndez, Thanh H Nguyen, Lokesh Joshi, F Javier Cañada, Jesús Jiménez-Barbero, Mária Benkő, Balázs Harrach, Mark J van Raaij
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139339 (2015)
The virulent form of turkey adenovirus 3 (TAdV-3), also known as turkey hemorrhagic enteritis virus (THEV), is an economically important poultry pathogen, while the avirulent form is used as a vaccine. TAdV-3 belongs to the genus Siadenovirus. The ca
Externí odkaz:
https://doaj.org/article/a156d06cf845405b86d97a4de08aa685
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104592 (2014)
Trans-3,5-dimethoxy-4'-hydroxystilbene (PTER), a natural dimethylated analog of resveratrol, preferentially induces certain cancer cells to undergo apoptosis and could thus have a role in cancer chemoprevention. Peroxisome proliferator-activated rece
Externí odkaz:
https://doaj.org/article/2c0b65f71ac544d788a595b831c9bfe3
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114373 (2014)
Adenoviruses are non-enveloped icosahedral viruses with trimeric fibre proteins protruding from their vertices. There are five known genera, from which only Mastadenoviruses have been widely studied. Apart from studying adenovirus as a biological mod
Externí odkaz:
https://doaj.org/article/8b005e3e357a456d908ef745075bf122
Autor:
Abhimanyu K. Singh, Brent De Wijngaert, Marc Bijnens, Kris Uyttersprot, Hoai Nguyen, Sergio E. Martinez, Dominique Schols, Piet Herdewijn, Christophe Pannecouque, Eddy Arnold, Kalyan Das
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Structures trapping a variety of functional and conformational states of HIV-1 reverse transcriptase (RT) have been determined by X-ray crystallography. These structures have played important roles in explaining the mechanisms of catalysis, inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52941d8f6fb7c540f7f5e6b1e3c487f2
https://doi.org/10.1073/pnas.2203660119
https://doi.org/10.1073/pnas.2203660119
Autor:
Kalyan Das, Abhimanyu K. Singh
The enzyme reverse transcriptase (RT) plays a central role in the life cycle of human immunodeficiency virus (HIV), and RT has been an important drug target. Elucidations of the RT structures trapping and detailing the enzyme at various functional an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c191f62795acd370674aa01a0092e93
https://lirias.kuleuven.be/handle/20.500.12942/695278
https://lirias.kuleuven.be/handle/20.500.12942/695278
Autor:
Abhimanyu K. Singh, Brent De Wijngaert, Marc Bijnens, Kris Uyttersprot, Hoai Nguyen, Sergio E. Martinez, Dominique Schols, Piet Herdewijn, Christophe Pannecouque, Eddy Arnold, Kalyan Das
Structures trapping a verity of functional and conformational states of HIV-1 reverse transcriptase (RT) have been determined by X-ray crystallography. These structures have played important roles in understanding the mechanisms of catalysis, inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3819f0904e698df8f1bda354ba9ab824
https://doi.org/10.1101/2022.02.27.482155
https://doi.org/10.1101/2022.02.27.482155
Autor:
Hoai Nguyen, Weijie Gu, Dominique Schols, Abhimanyu K. Singh, Jef Rozenski, Piet Herdewijn, Steven De Jonghe, Sergio E. Martinez, Kalyan Das
Publikováno v:
European journal of medicinal chemistry. 225
HIV-1 reverse transcriptase (RT) plays a central role in the viral life cycle, and roughly half of the FDA-approved anti-HIV drugs are targeting RT. Nucleoside analogs (NRTIs) require cellular phosphorylation for binding to RT, and to bypass this rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dda594608663771fe952d3f5cc952e8
https://pubmed.ncbi.nlm.nih.gov/34425311
https://pubmed.ncbi.nlm.nih.gov/34425311
Autor:
Erik de Heuvel, Abhimanyu K. Singh, Ewald Edink, Tiffany van der Meer, Melanie van der Woude, Payman Sadek, Mikkel P. Krell-Jørgensen, Toine van den Bergh, Johan Veerman, Guy Caljon, Titilola D. Kalejaiye, Maikel Wijtmans, Louis Maes, Harry P. de Koning, Geert Jan Sterk, Marco Siderius, Iwan J.P. de Esch, David G. Brown, Rob Leurs
Publikováno v:
Bioorganic and Medicinal Chemistry, 27(18), 3998-4012. Elsevier Limited
de Heuvel, E, Singh, A K, Edink, E, van der Meer, T, van der Woude, M, Sadek, P, Krell-Jørgensen, M P, van den Bergh, T, Veerman, J, Caljon, G, Kalejaiye, T D, Wijtmans, M, Maes, L, de Koning, H P, Jan Sterk, G, Siderius, M, de Esch, I J P, Brown, D G & Leurs, R 2019, ' Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors ', Bioorganic and Medicinal Chemistry, vol. 27, no. 18, pp. 3998-4012 . https://doi.org/10.1016/j.bmc.2019.06.027
de Heuvel, E, Singh, A K, Edink, E, van der Meer, T, van der Woude, M, Sadek, P, Krell-Jørgensen, M P, van den Bergh, T, Veerman, J, Caljon, G, Kalejaiye, T D, Wijtmans, M, Maes, L, de Koning, H P, Jan Sterk, G, Siderius, M, de Esch, I J P, Brown, D G & Leurs, R 2019, ' Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors ', Bioorganic and Medicinal Chemistry, vol. 27, no. 18, pp. 3998-4012 . https://doi.org/10.1016/j.bmc.2019.06.027
Several 3',5'-cyclic nucleotide phosphodiesterases (PDEs) have been validated as good drug targets for a large variety of diseases. Trypanosoma brucei PDEB1 (TbrPDEB1) has been designated as a promising drug target for the treatment of human African
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7977de212c1b702b8e7a0a91b90f42f3
https://doi.org/10.1016/j.bmc.2019.06.027
https://doi.org/10.1016/j.bmc.2019.06.027
Autor:
Alemu Kebede, A. V. Gholap, Abhimanyu K. Singh, Neeraj Kumar Giri, Awadhesh Kumar Rai, Geeta Watal, Prashant Kumar Rai
Publikováno v:
Lasers in Medical Science. 28:579-587
Impurity-free, controlled synthesis of iron oxide nanoparticle, in ultrapure water and chitosan, using laser ablation technique and its application for type II diabetes management through oral delivery of insulin-loaded iron oxide-chitosan nanocompos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339855599252d7221e2d6640e9b6d312
https://doi.org/10.1007/s10103-012-1106-3
https://doi.org/10.1007/s10103-012-1106-3
Publikováno v:
Instrumentation Science and Technology, 37(1), 50-60
Instrumentation Science and Technology 37 (2009) 1
Instrumentation Science and Technology 37 (2009) 1
Gold nanoparticles were synthesized by laser ablation of a gold metallic disc at wavelengths of 532 nm and 355 nm with 7 ns pulse duration in the pure water. The colloidal gold nanoparticles were characterized by ultraviolet-visible absorption spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6a7ebfad0da0447dbdedbb00aeeb0e
https://doi.org/10.1080/10739140802584731
https://doi.org/10.1080/10739140802584731