Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Abhilash I, Chiramel"'
Autor:
Rajeswari Basu, Richard Dambra, Di Jiang, Sophia A. Schätzlein, Shu Njiyang, Joseph Ashour, Abhilash I. Chiramel, Adam Vigil, Vladimir V. Papov
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT The rapidly developing field of oncolytic virus (OV) therapy necessitates the development of new and improved analytical approaches for the characterization of the virus during production and development. Accurate monitoring and absolute qua
Externí odkaz:
https://doaj.org/article/d524a8f06b7342df898d18acc35d3bd4
Autor:
Gayatri Subramanian, Adam Hage, Friederike Feldmann, Abhilash I. Chiramel, Kristin L. McNally, Gail L. Sturdevant, Paul A. Beare, Sonja M. Best
Publikováno v:
Viruses, Vol 16, Iss 9, p 1377 (2024)
The unprecedented research effort associated with the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) included several extensive proteomic studies that identified host proteins that interact with individual viral gene produc
Externí odkaz:
https://doaj.org/article/b6f86d9456e7430c99d8646e2ca3fe4f
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Autor:
Guoli Shi, Abhilash I. Chiramel, Tiansheng Li, Kin Kui Lai, Adam D. Kenney, Ashley Zani, Adrian C. Eddy, Saliha Majdoul, Lizhi Zhang, Tirhas Dempsey, Paul A. Beare, Swagata Kar, Jonathan W. Yewdell, Sonja M. Best, Jacob S. Yount, Alex A. Compton
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in immunocompromised individuals is associated with prolonged virus shedding and evolution of viral variants. Rapamycin and its analogs (rapalogs, including everolimus, temsirolim
Externí odkaz:
https://doaj.org/article/54c02ef4c7e14f2d8fd82a8b248817d9
Autor:
Luwanika Mlera, Danielle K. Offerdahl, David W. Dorward, Aaron Carmody, Abhilash I. Chiramel, Sonja M. Best, Marshall E. Bloom
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1378-1389 (2021)
The vector-borne flaviviruses (VBFVs) are well known for causing great misery and death in humans worldwide. The VBFVs include those transmitted by mosquitos, such as Zika virus (ZIKV), dengue virus; and those transmitted by ticks including the tick-
Externí odkaz:
https://doaj.org/article/d4d892f0a3a84e28937b0e437a4aabfb
Autor:
Rebecca M Broeckel, Friederike Feldmann, Kristin L McNally, Abhilash I Chiramel, Gail L Sturdevant, Jacqueline M Leung, Patrick W Hanley, Jamie Lovaglio, Rebecca Rosenke, Dana P Scott, Greg Saturday, Fadila Bouamr, Angela L Rasmussen, Shelly J Robertson, Sonja M Best
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009678 (2021)
Kyasanur Forest disease virus (KFDV) and the closely related Alkhurma hemorrhagic disease virus (AHFV) are emerging flaviviruses that cause severe viral hemorrhagic fevers in humans. Increasing geographical expansion and case numbers, particularly of
Externí odkaz:
https://doaj.org/article/e75b0f0e8a774ab2b7bf41f32357fe43
Autor:
Scott Martin, Abhilash I. Chiramel, Marie Luisa Schmidt, Yu-Chi Chen, Nadia Whitt, Ari Watt, Eric C. Dunham, Kyle Shifflett, Shelby Traeger, Anne Leske, Eugen Buehler, Cynthia Martellaro, Janine Brandt, Lisa Wendt, Andreas Müller, Stephanie Peitsch, Sonja M. Best, Jürgen Stech, Stefan Finke, Angela Römer-Oberdörfer, Allison Groseth, Heinz Feldmann, Thomas Hoenen
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background The 2014–2016 Ebola virus (EBOV) outbreak in West Africa highlighted the need for improved therapeutic options against this virus. Approaches targeting host factors/pathways essential for the virus are advantageous because they
Externí odkaz:
https://doaj.org/article/de07dea36f0548debf36fe428049f3e0
Autor:
Ted Hackstadt, Abhilash I. Chiramel, Forrest H. Hoyt, Brandi N. Williamson, Cheryl A. Dooley, Paul A. Beare, Emmie de Wit, Sonja M. Best, Elizabeth R. Fischer
Publikováno v:
Viruses, Vol 13, Iss 9, p 1798 (2021)
A variety of immunolabeling procedures for both light and electron microscopy were used to examine the cellular origins of the host membranes supporting the SARS-CoV-2 replication complex. The endoplasmic reticulum has long been implicated as a sourc
Externí odkaz:
https://doaj.org/article/da0bb646eddd4b82911ad4eb61c121bb
Autor:
Mukta Dutta, Shelly J. Robertson, Atsushi Okumura, Dana P. Scott, Jean Chang, Jeffrey M. Weiss, Gail L. Sturdevant, Friederike Feldmann, Elaine Haddock, Abhilash I. Chiramel, Sanket S. Ponia, Jonathan D. Dougherty, Michael G. Katze, Angela L. Rasmussen, Sonja M. Best
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 816-829 (2017)
The unprecedented 2013–2016 outbreak of Ebola virus (EBOV) resulted in over 11,300 human deaths. Host resistance to RNA viruses requires RIG-I-like receptor (RLR) signaling through the adaptor protein, mitochondrial antiviral signaling protein (MAV
Externí odkaz:
https://doaj.org/article/42e25f6aec7c4189ab3333c17d8efe8b
Autor:
Abhilash I. Chiramel, Nicholas R. Meyerson, Kristin L. McNally, Rebecca M. Broeckel, Vanessa R. Montoya, Omayra Méndez-Solís, Shelly J. Robertson, Gail L. Sturdevant, Kirk J. Lubick, Vinod Nair, Brian H. Youseff, Robin M. Ireland, Catharine M. Bosio, Kyusik Kim, Jeremy Luban, Vanessa M. Hirsch, R. Travis Taylor, Fadila Bouamr, Sara L. Sawyer, Sonja M. Best
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3269-3283.e6 (2019)
Summary: Tripartite motif-containing protein 5α (TRIM5α) is a cellular antiviral restriction factor that prevents early events in retrovirus replication. The activity of TRIM5α is thought to be limited to retroviruses as a result of highly specifi
Externí odkaz:
https://doaj.org/article/680b7a0b93c5469cbbde7dcdbb3d4d2d