Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Abhik Paul"'
Publikováno v:
Indian Pediatrics Case Reports, Vol 3, Iss 2, Pp 81-85 (2023)
Background: Langerhans cell histiocytosis (LCH) is a rare condition in which there is the proliferation of cells of the monocyte-dendritic cell lineage, including Langerhan's cells, with variable clinical manifestations and outcomes. Hepatic involvem
Externí odkaz:
https://doaj.org/article/3269eef53fb64888889e557ce2edd8ed
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2022)
Neurological conditions like neurodevelopmental disorders and neurodegenerative diseases are quite complex and often exceedingly difficult for patients. Most of these conditions are due to a mutation in a critical gene. There is no cure for the major
Externí odkaz:
https://doaj.org/article/ae74454ec3ae452892b97e913a11c04b
Autor:
Suresh SN, Janhavi Pandurangi, Ravi Murumalla, Vidyadhara DJ, Lakshmi Garimella, Achyuth Acharya, Shashank Rai, Abhik Paul, Haorei Yarreiphang, Malini S Pillai, Mridhula Giridharan, James P Clement, Phalguni Anand Alladi, Taslimarif Saiyed, Ravi Manjithaya
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 260-273 (2019)
Background: Plethora of efforts fails to yield a single drug to reverse the pathogenesis of Parkinson's disease (PD) and related α-synucleopathies. Methods: Using chemical biology, we identified a small molecule inhibitor of c-abl kinase, PD180970 t
Externí odkaz:
https://doaj.org/article/5fa4a5ea36dd41c3a5a47d5140b05e73
Publikováno v:
Open Biology, Vol 9, Iss 6 (2019)
Normal brain development is highly dependent on the timely coordinated actions of genetic and environmental processes, and an aberration can lead to neurodevelopmental disorders (NDDs). Intellectual disability (ID) and autism spectrum disorders (ASDs
Externí odkaz:
https://doaj.org/article/028705ac0daf4ff89b95d43ca6cc0091
Autor:
Abhik Paul, Bharti Nawalpuri, Devanshi Shah, Shruthi Sateesh, Ravi S. Muddashetty, James P. Clement
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
SYNGAP1, a Synaptic Ras-GTPase activating protein, regulates synapse maturation during a critical developmental window. Heterozygous mutation in SYNGAP1 (SYNGAP1-/+) has been shown to cause Intellectual Disability (ID) in children. Recent studies hav
Externí odkaz:
https://doaj.org/article/75f35cb539954df3be246fbd968d50a1
Autor:
S. N. Suresh, Aravinda K. Chavalmane, Malini Pillai, Veena Ammanathan, D. J. Vidyadhara, Haorei Yarreiphang, Shashank Rai, Abhik Paul, James P. Clement, Phalguni A. Alladi, Ravi Manjithaya
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Mechanistic insights into aggrephagy, a selective basal autophagy process to clear misfolded protein aggregates, are lacking. Here, we report and describe the role of Estrogen Related Receptor α (ERRα, HUGO Gene Nomenclature ESRRA), new molecular p
Externí odkaz:
https://doaj.org/article/7773f462a4df4bb7a7da10d3bab13297
Publikováno v:
Mini-Reviews in Organic Chemistry. 20:5-34
Abstract: 5-Arylidene-2,4-thiazolidinedione (5-A-TZD) is an emerging precursor molecule in medicinal chemistry for discovering multifunctional therapeutic agents. For synthesizing this precursor molecule, Knoevenagel Condensation (KC) is one of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bf4e446ef284e72311bbcc324e54794
https://doi.org/10.2174/1570193x19666220331155705
https://doi.org/10.2174/1570193x19666220331155705
Publikováno v:
Journal of Materials Chemistry C. 11:6750-6759
Modulating the SCO behaviour in porous coordination polymers is not only an excellent way to address the challenges associated with high-order data storage, but the colour change involved in the process reveals their thermal and optical sensors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f20130d7dd33a75dedabb1c4fb2482bc
https://doi.org/10.1039/d3tc00064h
https://doi.org/10.1039/d3tc00064h
Publikováno v:
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems. 41:4385-4396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c5adf4734cae89748b8841e98fc9c5
https://doi.org/10.1109/tcad.2022.3200914
https://doi.org/10.1109/tcad.2022.3200914
Publikováno v:
Current Topics in Medicinal Chemistry. 22:1160-1176
Abstract: Indazole is a vital nitrogen-containing heterocyclic unit in organic and medicinal chemistry research and a helpful precursor molecule for the production of various types of encirclement heterocycles. Indazole analogues are diverse pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e68ec64877b503d8ec5f495ef949a4
https://doi.org/10.2174/1568026622666220415224139
https://doi.org/10.2174/1568026622666220415224139