Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Abhik, Sen"'
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 1, Pp 215-225 (2021)
Mutations to the cholesterol transport protein apolipoprotein E (ApoE) have been identified as a major risk factor for the development of sporadic or late-onset Alzheimer’s disease (AD), with the e4 allele representing an increased risk and the rar
Externí odkaz:
https://doaj.org/article/1a2823261b964972accd80c50d1493a8
Autor:
Thomas J. Nelson, Abhik Sen
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 10-18 (2019)
Abstract Introduction Apolipoprotein E4 (apoE4) is the predominant risk factor for late‐onset Alzheimer's disease (AD), but the question of which structural differences might explain its effect remains unclear. Methods We compared high‐density li
Externí odkaz:
https://doaj.org/article/466de1830a074926b7d6006e2d2dc158
Publikováno v:
Innate Immunity, Vol 27 (2021)
Genetic variations in the host TLRs genes play an important role in susceptibility and/or resistance to visceral leishmaniasis by altering the host-pathogen interaction. In this study, we investigated the association between polymorphisms of TLR4 (As
Externí odkaz:
https://doaj.org/article/6c9a669e342741ffb85aa9b6d85b2c52
Elucidation of conserved multi-epitope vaccine against Leishmania donovani using reverse vaccinology
Autor:
Manas Ranjan Dikhit, Abhik Sen
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-14
Autor:
Ravi Shankar, Suman Nayak, Sneha Singh, Abhik Sen, Nitesh Kumar, Rashmi Bhushan, Maansi Aggarwal, Prolay Das
Publikováno v:
ACS Applied Bio Materials. 6:1556-1565
Autor:
Tanvir Bamra, Taj Shafi, Sushmita Das, Manjay Kumar, Manas Ranjan Dikhit, Ajay Kumar, Ashish Kumar, Kumar Abhishek, Krishna Pandey, Abhik Sen, Pradeep Das
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Summary StatementLeishmania secretes over 151 proteins during in vitro cultivation. Cellular functions of one such novel protein: mevalonate kinase is discussed here; signifying its importance in Leishmania infection.Visceral Leishmaniasis is a persi
Externí odkaz:
https://doaj.org/article/923fdf5e84694a8e9bb7a6112ae87b51
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 2, Iss , Pp 100014- (2021)
Background: Vascular risk factors such as atherosclerosis, diabetes, and elevated homocysteine levels are strongly correlated with onset of Alzheimer's disease (AD). Emerging evidence indicates that blood coagulation protein thrombin is associated wi
Externí odkaz:
https://doaj.org/article/c2c83101daef4c86bf2e9b6a1b98fcd5
Autor:
Jaclyn Iannucci, Shelby L. Johnson, Mark Majchrzak, Benjamin J. Barlock, Fatemeh Akhlaghi, Navindra P. Seeram, Abhik Sen, Paula Grammas
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100862- (2020)
Proteins that regulate the coagulation cascade, including thrombin, are elevated in the brains of Alzheimer's disease (AD) patients. While studies using amyloid-based AD transgenic mouse models have implicated thrombin as a protein of interest, the r
Externí odkaz:
https://doaj.org/article/03ac6d10deab459f80d89734a98f9d4e
Autor:
Sneha Singh, Major Madhukar, Manas Ranjan Dikhit, Vidya Nand Ravidas, Krishna Pandey, Abhik Sen
Publikováno v:
The Journal of Infectious Diseases. 227:1132-1142
Background Post–kala-azar dermal leishmaniasis (PKDL), a dermal form of the disease, occurs in some visceral leishmaniasis (VL) patients following treatment. The PKDL disease mechanism is not yet clearly understood. Here we have studied the role of
Autor:
Ashish Kumar, Saravanan Vijaykumar, Manas Ranjan Dikhit, Kumar Abhishek, Rimi Mukherjee, Abhik Sen, Pradeep Das, Sushmita Das
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
MicroRNAs are small ribonucleic acid that act as an important regulator of gene expression at the molecular level. However, there is no comparative data on the regulation of microRNAs (miRNAs) in visceral leishmaniasis (VL) and post-kala-azar dermal
Externí odkaz:
https://doaj.org/article/d13421adc6cf4a2bb8e5e0bb5605bc65