Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Abhijit S Dighe"'
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211782 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0103060.].
Externí odkaz:
https://doaj.org/article/581a61f780c64d5881dc297237cc78d2
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103060 (2014)
Clinical trials on fracture repair have challenged the effectiveness of bone morphogenetic proteins (BMPs) but suggest that delivery of mesenchymal stem cells (MSCs) might be beneficial. It has also been reported that BMPs could not increase minerali
Externí odkaz:
https://doaj.org/article/b43dae39f4804d749ec36be15ff1aa5b
Autor:
Logan F. McColl, Xizhao Chen, Michael D. Solga, Kailo Schlegel, Sean P. Haughey, Peter I. Lobo, Kristen Fread, Eli Zunder, Ryan Cha, Stephen Park, J. Jared Christophel, Quanjun Cui, Abhijit S. Dighe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionBone morphogenetic proteins (BMPs) are used as key therapeutic agents for the treatment of difficult fractures. While their effects on osteoprogenitors are known, little is known about their effects on the immune system.MethodsWe used per
Externí odkaz:
https://doaj.org/article/6a95833bf15047f581910d926ff31bc1
Association of Fpr1 gene expression with osteogenesis and adipogenesis of adipose derived stem cells
Publikováno v:
Biochem Biophys Res Commun
Formyl peptide receptors (Fprs) play fundamental roles in multiple cell functions including promotion of osteogenesis and bone fracture healing. In this study, the role of Fpr1 gene in osteogenic and adipogenic differentiation of adipose derived stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658790d5dc48e722de9424fbb475ac97
https://doi.org/10.1016/j.bbrc.2021.08.044
https://doi.org/10.1016/j.bbrc.2021.08.044
Autor:
Eli R. Zunder, Joseph M. Hart, Abhijit S. Dighe, Charles R. Farber, Quang Le, Quanjun Cui, Vedavathi Madhu
Publikováno v:
World Journal of Stem Cells
Injuries to the postnatal skeleton are naturally repaired through successive steps involving specific cell types in a process collectively termed “bone regeneration”. Although complex, bone regeneration occurs through a series of well-orchestrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b18c5aa0a13ffd99b2a256490878929
https://doi.org/10.4252/wjsc.v13.i9.1248
https://doi.org/10.4252/wjsc.v13.i9.1248
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
It is estimated that, of the 7.9 million fractures sustained in the United States each year, 5% to 20% result in delayed or impaired healing requiring therapeutic intervention. Following fracture injury, there is an initial inflammatory response that
Externí odkaz:
https://doaj.org/article/b2fcaf03d4934f49b01fbd9e79f738e5
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Osteoarthritis is a common and debilitating joint disease that affects up to 30 million Americans, leading to significant disability, reduction in quality of life, and costing the United States tens of billions of dollars annually. Classically, osteo
Externí odkaz:
https://doaj.org/article/24aee1a473fe45099905ea5785dbf40e
Autor:
Logan F. McColl, Jason R. Kerrigan, Quanjun Cui, Kishan Mathur, Gina Beck, Sangamesh G. Kumbar, Michael R. Arul, Jonathan Nip, Vashaana Sahadeo, J. Jared Christophel, Matthew Q. Miller, Abhijit S. Dighe, Vedavathi Madhu, Stephen S. Park
IMPORTANCE: Osseous craniofacial defects are currently reconstructed with bone grafting, rigid fixation, free tissue transfer, and/or recombinant human bone morphogenetic protein 2. Although these treatment options often have good outcomes, they are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6530234c4e4d05d264be52fae71e5bf4
https://europepmc.org/articles/PMC6439804/
https://europepmc.org/articles/PMC6439804/
Publikováno v:
JAMA Facial Plastic Surgery. 18:391-394
The field of regenerative medicine aims at enhancing tissue healing and regeneration through the exogenous addition of therapeutic growth factors and cells, often in combination with tissue-compatible scaffolds. Perhaps the biggest advances in facial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2da834dbb56772230da81649d4cc0a
https://doi.org/10.1001/jamafacial.2016.0913
https://doi.org/10.1001/jamafacial.2016.0913
Autor:
Brian A. Fishero, J. Jared Christophel, Ching-Ju Li, Quanjun Cui, Abhijit S. Dighe, Nikita Kohli, Anusuya Das, Yong Lin
Publikováno v:
Cell and Tissue Research. 364:125-135
We have previously shown that the combined delivery of mesenchymal stem cells (MSCs), vascular endothelial growth factor (VEGF) and bone morphogenetic protein 6 (BMP-6) induces significantly more bone formation than that induced by the delivery of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0861831143906ae592bc6cad80305796
https://doi.org/10.1007/s00441-015-2301-x
https://doi.org/10.1007/s00441-015-2301-x