Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Abhijit Chakladar"'
Autor:
Vishwajeet Puri, Abhijit Chakladar, Joseph V. Virbasius, Silvana Konda, Aimee M. Powelka, My Chouinard, G. Nana Hagan, Richard Perugini, Michael P. Czech
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 2, Pp 465-471 (2007)
Cultured adipocyte cell lines are a model system widely used to study adipose function, but they exhibit significant physiological differences compared with primary cells from adipose tissue. Here we report short interfering RNA-based methodology to
Externí odkaz:
https://doaj.org/article/9672f2ebc43949cf91e680f69f793045
Autor:
Jay S. Loeffler, Neelanjan Mukherjee, Gary Zhai, James V. Alvarez, Pierre A. Robe, Arnab Chakravarti, David A. Frank, Peter McL. Black, Abhijit Chakladar
Publikováno v:
Translational Oncogenomics
Gliomas frequently display constitutive activation of the transcription factor STAT3, a protein that is known to be able to mediate neoplastic transformation. STAT3 regulates genes that play a central role in cellular survival, proliferation, self-re
Autor:
Aimee M. Powelka, Joseph V. Virbasius, Richard A. Perugini, Michael P. Czech, Vishwajeet Puri, Silvana Konda, Abhijit Chakladar, My T. Chouinard, G. Nana Hagan
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 2, Pp 465-471 (2007)
Cultured adipocyte cell lines are a model system widely used to study adipose function, but they exhibit significant physiological differences compared with primary cells from adipose tissue. Here we report short interfering RNA-based methodology to
Publikováno v:
Molecular and Cellular Biology. 20:697-701
Human IQGAP1 is a widely expressed 190-kDa Cdc42-, Rac1-, and calmodulin-binding protein that interacts with F-actin in vivo and that can cross-link F-actin microfilaments in vitro. Recent results have implicated IQGAP1 as a component of pathways via
Autor:
Abhijit Chakladar, Sekhar Chakrabarti
Publikováno v:
Intervirology. 41:127-131
We have investigated the serotype-specific glycoprotein gene (VP7) of a short electropherotype and subgroup I rotavirus (ID 45/2) recovered from a child suffering from acute diarrhea. The nucleotide sequence of the human (ID 45/2) rotavirus genome se
Autor:
Xiaoqing Tang, Juerg R. Straubhaar, Adilson L. Guilherme, Michael P. Czech, Sarah M. Nicoloro, Joseph V. Virbasius, Abhijit Chakladar, Silvana Konda, Aimee M. Powelka
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(7)
The insulin-regulated glucose transporter GLUT4 is a key modulator of whole body glucose homeostasis, and its selective loss in adipose tissue or skeletal muscle causes insulin resistance and diabetes. Here we report an RNA interference-based screen
Autor:
Timothy C. Wang, Lindsay J. Wojtukiewicz, Shi Lei, Alexander Dubeykovskiy, Abhijit Chakladar, Jitesh Pratap
Publikováno v:
Biochemical and biophysical research communications. 336(1)
While Wnt and Ras signaling pathways are activated during progression of colorectal cancers, many of their important downstream targets remain to be elucidated. The gastrin gene encodes for a family of peptide growth factors that are commonly upregul
Publikováno v:
The Journal of biological chemistry. 279(41)
The transforming growth factor-beta (TGF-beta) and Wnt/wingless pathways play critical roles in the specification of cell fate during development and also contribute to cancer formation and progression. Whereas Wnt signaling is clearly pro-oncogenic,
Autor:
Arnab, Chakravarti, Abhijit, Chakladar, Meaghan A, Delaney, Douglas E, Latham, Jay S, Loeffler
Publikováno v:
Cancer research. 62(15)
Resistance to conventional adjuvant therapies (i.e., chemotherapy and radiation) has been well documented in malignant gliomas. Unlike many other tumor types, combined modality therapy involving radiation and chemotherapy has failed to appreciably en
Publikováno v:
Gastroenterology. 124:A472
Background and Aims: Transtorming growth factor !3 (TGF-13)/gmads and Wnt pathways play a critical role in both repressing and progressing gastrointestinal cancers. Various mutations of TI3RII, Smad2, Smad4, APC, and [3-eatenin are associated with a