Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Abhijay Kumar"'
Autor:
Elizabeth R. Lawlor, Costas A. Lyssiotis, Jolanta Grembecka, Tomasz Cierpicki, Dong Chen, Trupta Purohit, Joshua Bradin, Zeribe C. Nwosu, Elena Haarer, Alessandra X. Garcia, Ramon Ocadiz Ruiz, Abhijay Kumar, Laurie K. Svoboda, Allegra G. Hawkins, April A. Apfelbaum, Jennifer A. Jiménez
shRNA sequences, plasmid information, western blot antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139626eab5c5eba6e20a18d4a1d85c80
https://doi.org/10.1158/1541-7786.22526064
https://doi.org/10.1158/1541-7786.22526064
Autor:
Elizabeth R. Lawlor, Costas A. Lyssiotis, Jolanta Grembecka, Tomasz Cierpicki, Dong Chen, Trupta Purohit, Joshua Bradin, Zeribe C. Nwosu, Elena Haarer, Alessandra X. Garcia, Ramon Ocadiz Ruiz, Abhijay Kumar, Laurie K. Svoboda, Allegra G. Hawkins, April A. Apfelbaum, Jennifer A. Jiménez
Supplementary Figure S1. Real-time cell proliferation analysis of shATF4, MI-503 treatment, and dox-inducible shMEN1 knockdown in Ewing sarcoma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65896b8b3795e1db6d930758a68a4535
https://doi.org/10.1158/1541-7786.22526076
https://doi.org/10.1158/1541-7786.22526076
Autor:
Elizabeth R. Lawlor, Costas A. Lyssiotis, Jolanta Grembecka, Tomasz Cierpicki, Dong Chen, Trupta Purohit, Joshua Bradin, Zeribe C. Nwosu, Elena Haarer, Alessandra X. Garcia, Ramon Ocadiz Ruiz, Abhijay Kumar, Laurie K. Svoboda, Allegra G. Hawkins, April A. Apfelbaum, Jennifer A. Jiménez
Supplementary Figure S4. Publicly Available RNA-Seq Data of EWS-FLI1 Knockdown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ab7ff0ebd69aefeb2d61988fb673a6
https://doi.org/10.1158/1541-7786.22526067.v1
https://doi.org/10.1158/1541-7786.22526067.v1
Autor:
Elizabeth R. Lawlor, Costas A. Lyssiotis, Jolanta Grembecka, Tomasz Cierpicki, Dong Chen, Trupta Purohit, Joshua Bradin, Zeribe C. Nwosu, Elena Haarer, Alessandra X. Garcia, Ramon Ocadiz Ruiz, Abhijay Kumar, Laurie K. Svoboda, Allegra G. Hawkins, April A. Apfelbaum, Jennifer A. Jiménez
Supplementary Figure S2. Effect of shFLI1 knockdown in CHLA10 Ewing sarcoma cells and Publicly Available ChIP-seq of EWS-FLI1 at the ATF4 and SSP Gene Promoters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2a3fc7146a3c6cead12af9dd037332
https://doi.org/10.1158/1541-7786.22526073
https://doi.org/10.1158/1541-7786.22526073
Autor:
Elizabeth R. Lawlor, Costas A. Lyssiotis, Jolanta Grembecka, Tomasz Cierpicki, Dong Chen, Trupta Purohit, Joshua Bradin, Zeribe C. Nwosu, Elena Haarer, Alessandra X. Garcia, Ramon Ocadiz Ruiz, Abhijay Kumar, Laurie K. Svoboda, Allegra G. Hawkins, April A. Apfelbaum, Jennifer A. Jiménez
Ewing sarcomas are driven by EWS–ETS fusions, most commonly EWS-FLI1, which promotes widespread metabolic reprogramming, including activation of serine biosynthesis. We previously reported that serine biosynthesis is also activated in Ewing sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2320fed454fc87a39bb75490b138e17
https://doi.org/10.1158/1541-7786.c.6544995.v1
https://doi.org/10.1158/1541-7786.c.6544995.v1
Autor:
Elizabeth R. Lawlor, Costas A. Lyssiotis, Jolanta Grembecka, Tomasz Cierpicki, Dong Chen, Trupta Purohit, Joshua Bradin, Zeribe C. Nwosu, Elena Haarer, Alessandra X. Garcia, Ramon Ocadiz Ruiz, Abhijay Kumar, Laurie K. Svoboda, Allegra G. Hawkins, April A. Apfelbaum, Jennifer A. Jiménez
Primer Sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51df260c5747a4b21f70aefdf2b59076
https://doi.org/10.1158/1541-7786.22526061.v1
https://doi.org/10.1158/1541-7786.22526061.v1
Autor:
Elizabeth R. Lawlor, Costas A. Lyssiotis, Jolanta Grembecka, Tomasz Cierpicki, Dong Chen, Trupta Purohit, Joshua Bradin, Zeribe C. Nwosu, Elena Haarer, Alessandra X. Garcia, Ramon Ocadiz Ruiz, Abhijay Kumar, Laurie K. Svoboda, Allegra G. Hawkins, April A. Apfelbaum, Jennifer A. Jiménez
Supplementary Figure S3. Timecourse for the effect of MI-503 on ATF4 in Ewing sarcoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfed48a416a70fcb4d1fe64339f5cf1
https://doi.org/10.1158/1541-7786.22526070
https://doi.org/10.1158/1541-7786.22526070
Autor:
Ramon Ocadiz Ruiz, Jennifer A. Jiménez, Abhijay Kumar, Jolanta Grembecka, Elena Haarer, April A. Apfelbaum, Elizabeth R. Lawlor, Allegra G. Hawkins, Alessandra X. Garcia, Dong Chen, Costas A. Lyssiotis, Laurie K. Svoboda, Zeribe C. Nwosu, Trupta Purohit, Joshua Bradin, Tomasz Cierpicki
Publikováno v:
Mol Cancer Res
Ewing sarcomas are driven by EWS–ETS fusions, most commonly EWS-FLI1, which promotes widespread metabolic reprogramming, including activation of serine biosynthesis. We previously reported that serine biosynthesis is also activated in Ewing sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ae2c38bed28d8428dba77881d2961b
https://europepmc.org/articles/PMC8462528/
https://europepmc.org/articles/PMC8462528/
Autor:
Olivier Mercey, Alice Meunier, Eva J. Brotslaw, Michelle S. Levine, Andrew J. Holland, Brian J. Mitchell, Nathalie Spassky, Philippe Rostaing, Abhijay Kumar, Gina M. LoMastro, Valerie Gomez
Publikováno v:
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2019, ⟨10.1038/s41556-019-0427-x⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2019, ⟨10.1038/s41556-019-0427-x⟩
Nature cell biology
International audience; Multiciliated cells (MCCs) amplify large numbers of centrioles that convert into basal bodies, which are required for producing multiple motile cilia. Most centrioles amplified by MCCs grow on the surface of organelles called
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efe3c46261e3862c13e4fedcf6f9fdc
https://hal.archives-ouvertes.fr/hal-02403074/document
https://hal.archives-ouvertes.fr/hal-02403074/document
Autor:
Ramon Ocadiz Ruiz, Jennifer A. Jiménez, Costas A. Lyssiotis, Abhijay Kumar, Samuel A. Kerk, Jolanta Grembecka, Elizabeth R. Lawlor, April A. Apfelbaum
Publikováno v:
Cancer Research. 80:B37-B37
s: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada Ewing sarcoma (ES) is an aggressive bone and soft-tissue tumor, most commonly driven by the EWS/FLI1 fusion oncogene. Previous work h