Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Abhigyan, Sengupta"'
Publikováno v:
The journal of physical chemistry. B. 125(31)
Prolyl isomerization is recognized as one of the key regulatory mechanisms, which plays a crucial role in cell signaling, ion channel gating, phage virus infection, and molecular timing. This isomerization is usually slow but often accelerated by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8ce35155bd3d181ecf1c645d0ca7dd8
https://pubmed.ncbi.nlm.nih.gov/34279937
https://pubmed.ncbi.nlm.nih.gov/34279937
Autor:
Abhigyan Sengupta, Matthias Rief
Publikováno v:
Proc Natl Acad Sci U S A
Protein folding is a complex diffusive process on a high-dimensional energy surface (1, 2). Gaining detailed insight into the folding energy landscape is an experimental challenge. First, most measurements can observe only one coordinate and provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7333fba9e85350562707b15fab5e1b2
https://doi.org/10.1073/pnas.2102946118
https://doi.org/10.1073/pnas.2102946118
Publikováno v:
Journal of Physical Chemistry B
Prolyl isomerization is recognized as one of the key regulatory mechanisms, which plays a crucial role in cell signaling, ion channel gating, phage virus infection, and molecular timing. This isomerization is usually slow but often accelerated by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc845acfc4e94578ac7d070a19f9bdfc
https://zenodo.org/record/6258601
https://zenodo.org/record/6258601
Publikováno v:
The journal of physical chemistry. B. 124(51)
The preponderance of a specific d- or l-chirality in fats, sugars, amino acids, nucleic acids, and so on is ubiquitous in nature, yet the biological origin of such chiral dominance (i.e., with one enantiomer overwhelmingly present) remains an open qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356858d4d22ba5d7456829e9f138b68f
https://pubmed.ncbi.nlm.nih.gov/33296203
https://pubmed.ncbi.nlm.nih.gov/33296203
Publikováno v:
The Journal of Chemical Physics. 154:155101
The cell is an extremely crowded environment, which is known to have a profound impact on the thermodynamics, functionality, and conformational stability of biomolecules. Speculations from recent theoretical molecular dynamics studies suggest an intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3fc2fb14b7a8e5ad68ba3147d718e2
https://doi.org/10.1063/5.0045492
https://doi.org/10.1063/5.0045492
Publikováno v:
The Journal of Physical Chemistry B. 120:10615-10627
In light of the current models for an early RNA-based universe, the potential influence of simple amino acids on tertiary folding of ribozymal RNA into biochemically competent structures is speculated to be of significant evolutionary importance. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc52d57ca241d4a63fb56caa0b7d7f1d
https://doi.org/10.1021/acs.jpcb.6b05840
https://doi.org/10.1021/acs.jpcb.6b05840
Amino acid and nucleic acid interactions are central in biology and may have played a role in the evolutionary development of protein-based life from an early "RNA Universe." To explore the possible role of single amino acids in promoting nucleic aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a154e4f817e9c4429e4880ac1929e70d
https://europepmc.org/articles/PMC6224135/
https://europepmc.org/articles/PMC6224135/
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 140:240-248
The role of Mg2+ ion in flavin (flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN)) recognition by RNA aptamer has been explored through steady state and time-resolved fluorescence, circular dichroism (CD), thermal melting (TM) and iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a1d92ac7d2dd809e035cf2884a5d9b2
https://doi.org/10.1016/j.jphotobiol.2014.08.007
https://doi.org/10.1016/j.jphotobiol.2014.08.007
Publikováno v:
The Journal of Physical Chemistry B. 119:2363-2371
The excited state proton transfer (ESPT) dynamics of a potentially important anticancer drug, Topotecan (TPT), has been explored in aqueous reverse micelle (RM) using steady-state and time-resolved fluorescence measurements. Both the time-resolved em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc72051c14b0b8f11831beaa63de414
https://doi.org/10.1021/jp5066902
https://doi.org/10.1021/jp5066902
Autor:
Arnab Mukherjee, Partha Hazra, Abhigyan Sengupta, Raj Kumar Koninti, Reman K. Singh, Krishna Gavvala
Publikováno v:
The Journal of Physical Chemistry B. 118:1881-1890
Here, we investigate the effect of urea in the unfolding dynamics of flavin adenine dinucleotide (FAD), an important enzymatic cofactor, through steady state, time-resolved fluorescence spectroscopic and molecular dynamics (MD) simulation studies. St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca79185ff759b8b18b110ccfe25b5db
https://doi.org/10.1021/jp412339a
https://doi.org/10.1021/jp412339a