Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Abhi Aggarwal"'
Publikováno v:
eLife, Vol 12 (2024)
Intracellular levels of the amino acid aspartate are responsive to changes in metabolism in mammalian cells and can correspondingly alter cell function, highlighting the need for robust tools to measure aspartate abundance. However, comprehensive und
Externí odkaz:
https://doaj.org/article/ffa31383e89e4b9381824921fba7f261
Autor:
Yusuke Nasu, Abhi Aggarwal, Giang N. T. Le, Camilla Trang Vo, Yuki Kambe, Xinxing Wang, Felix R. M. Beinlich, Ashley Bomin Lee, Tina R. Ram, Fangying Wang, Kelsea A. Gorzo, Yuki Kamijo, Marc Boisvert, Suguru Nishinami, Genki Kawamura, Takeaki Ozawa, Hirofumi Toda, Grant R. Gordon, Shaoyu Ge, Hajime Hirase, Maiken Nedergaard, Marie-Eve Paquet, Mikhail Drobizhev, Kaspar Podgorski, Robert E. Campbell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract l-Lactate is increasingly appreciated as a key metabolite and signaling molecule in mammals. However, investigations of the inter- and intra-cellular dynamics of l-lactate are currently hampered by the limited selection and performance of l-
Externí odkaz:
https://doaj.org/article/92c1078698bf4a70b5ef20a844149591
Autor:
Lorenzo Calzado-Reyes, Ulku Cuhadar, Carlos Pascual-Caro, Aman S. Aberra, Abhi Aggarwal, Kaspar Podgorski, Michael B. Hoppa, Jaime De Juan-Sanz
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S301- (2023)
Externí odkaz:
https://doaj.org/article/aab42097b6514b11aee8c5a65806b305
Autor:
Yusuke Nasu, Ciaran Murphy-Royal, Yurong Wen, Jordan N. Haidey, Rosana S. Molina, Abhi Aggarwal, Shuce Zhang, Yuki Kamijo, Marie-Eve Paquet, Kaspar Podgorski, Mikhail Drobizhev, Jaideep S. Bains, M. Joanne Lemieux, Grant R. Gordon, Robert E. Campbell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
l-lactate is an important intercellular energy currency. Here the authors report a genetically encoded biosensor eLACCO1.1 to monitor extracellular l-lactate; they use eLACCO1.1 to image extracellular l-lactate in cultured mammalian cells and brain t
Externí odkaz:
https://doaj.org/article/56b5eb5b8e5543099fe7a7880622d7ac
Autor:
Sheng-Yi Wu, Yurong Wen, Nelson B C Serre, Cathrine Charlotte Heiede Laursen, Andrea Grostøl Dietz, Brian R Taylor, Mikhail Drobizhev, Rosana S Molina, Abhi Aggarwal, Vladimir Rancic, Michael Becker, Klaus Ballanyi, Kaspar Podgorski, Hajime Hirase, Maiken Nedergaard, Matyáš Fendrych, M Joanne Lemieux, Daniel F Eberl, Alan R Kay, Robert E Campbell, Yi Shen
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001772 (2022)
Potassium ion (K+) plays a critical role as an essential electrolyte in all biological systems. Genetically-encoded fluorescent K+ biosensors are promising tools to further improve our understanding of K+-dependent processes under normal and patholog
Externí odkaz:
https://doaj.org/article/3acdec6eadb747dba6da2bd4ef33714b
Autor:
Yong Qian, Danielle M Orozco Cosio, Kiryl D Piatkevich, Sarah Aufmkolk, Wan-Chi Su, Orhan T Celiker, Anne Schohl, Mitchell H Murdock, Abhi Aggarwal, Yu-Fen Chang, Paul W Wiseman, Edward S Ruthazer, Edward S Boyden, Robert E Campbell
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000965 (2020)
Near-infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs) can provide advantages over visible wavelength fluorescent GECIs in terms of reduced phototoxicity, minimal spectral cross talk with visible light excitable optogenetic too
Externí odkaz:
https://doaj.org/article/c61b9ef989474c1c9da003b377045026
Publikováno v:
Spectrum, Iss 1 (2018)
The process of determining the exact order of nucleotides in DNA is a crucial component of a wide variety of research applications known as DNA sequencing. Over the last fifty years, several DNA sequencing technologies have been well characterized th
Externí odkaz:
https://doaj.org/article/b8806613bdd64982a09e85eacc5cfc32
Autor:
Yusuke Nasu, Abhi Aggarwal, Giang N. T. Le, Yuki Kamijo, Marc Boisvert, Marie-Eve Paquet, Mikhail Drobizhev, Kaspar Podgorski, Robert E. Campbell
l-Lactate is increasingly appreciated as a key metabolite and signaling molecule in mammals. To enable investigations of both the inter- and intra-cellular dynamics ofl-Lactate, we develop a second-generation green fluorescent extracellularl-Lactate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d4a29262d0ebe4ba5b5b03195835e5
https://doi.org/10.1101/2022.12.27.522013
https://doi.org/10.1101/2022.12.27.522013
Autor:
Ulku Cuhadar, Lorenzo Calzado-Reyes, Carlos Pascual-Caro, Aman S. Aberra, Abhi Aggarwal, Kaspar Podgorski, Michael B. Hoppa, Jaime de Juan-Sanz
The fine control of synaptic function requires robust trans-synaptic molecular interactions. However, it remains poorly understood how the landscape of trans-synaptic bridges dynamically remodels to reflect functional states of the synapse. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80677f08bac7270857285d61edc8ddeb
https://doi.org/10.1101/2022.07.03.498586
https://doi.org/10.1101/2022.07.03.498586
Autor:
Mariam Moshiri, Douglas S. Katz, Sean S. London, Jonathan W. Revels, Courtney B. Dey, Abhi Aggarwal, Christine O. Menias
Publikováno v:
Current Problems in Diagnostic Radiology. 49:431-446
Endometrial abnormalities develop in female patients of all ages. Symptoms related to endometrial pathologies are among the most common causes of gynecologist office visits, with the radiologists playing an important role in endometrial evaluation. I