Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Abhalaxmi Singh"'
Autor:
Kurt Bachmaier, Andrew Stuart, Abhalaxmi Singh, Amitabha Mukhopadhyay, Sreeparna Chakraborty, Zhigang Hong, Li Wang, Yoshikazu Tsukasaki, Mark Maienschein-Cline, Balaji B. Ganesh, Prasad Kanteti, Jalees Rehman, Asrar B. Malik
Publikováno v:
ACS Nano. 16:4084-4101
The complex involvement of neutrophils in inflammatory diseases makes them intriguing but challenging targets for therapeutic intervention. Here, we tested the hypothesis that varying endocytosis capacities would delineate functionally distinct neutr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c95fcf9378b85c14754eabc837d336
https://doi.org/10.1021/acsnano.1c09762
https://doi.org/10.1021/acsnano.1c09762
Publikováno v:
Microscopy and Microanalysis. 28:1108-1110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9554fd14315bb765c766fac79ade99ee
https://doi.org/10.1017/s1431927622004688
https://doi.org/10.1017/s1431927622004688
Autor:
Abhalaxmi Singh, Sreeparna Chakraborty, Sing Wan Wong, Nicole A. Hefner, Andrew Stuart, Abdul S. Qadir, Amitabha Mukhopadhyay, Kurt Bachmaier, Jae-Won Shin, Jalees Rehman, Asrar B. Malik
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(15)
The pathogenesis of lung fibrosis involves hyperactivation of innate and adaptive immune pathways that release inflammatory cytokines and growth factors such as tumor growth factor (TGF)β1 and induce aberrant extracellular matrix protein production.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da62c578c70d6f7f3a8a11bdbb9675e4
https://pubmed.ncbi.nlm.nih.gov/35377803
https://pubmed.ncbi.nlm.nih.gov/35377803
Autor:
Andrew B. Stuart, Mark Maienschein-Cline, Prasad Kanteti, Sreeparna Chakraborty, Asrar B. Malik, Abhalaxmi Singh, Jalees Rehman, Yoshikazu Tsukasaki, Xiaopei Gao, Amitabha Mukhopadhyay, Kurt Bachmaier, Zhigang Hong
Inflammatory tissue injury such as acute lung injury (ALI) is a disorder that leads to respiratory failure, a major cause of morbidity and mortality worldwide. Excessive neutrophil influx is a critical pathogenic factor in the development of ALI. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49f112680996eb728197dae29fd94eda
https://doi.org/10.1101/2020.06.30.180927
https://doi.org/10.1101/2020.06.30.180927
Autor:
Vikas Nandwana, Gefei Zhang, John Higham, Vinayak P. Dravid, Yue Li, Abhalaxmi Singh, Pottumarthi V. Prasad, Marisa M. You, Tiffany S. Zheng
Publikováno v:
Journal of materials chemistry. B. 6(7)
We report magnetic nanostructure-stabilized lipid nanocapsules (MLNCs) that show superior structural stability and theranostic properties compared to conventional lipid-based nanocarriers. As therapeutic nanocarriers, the MLNCs exhibit a therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87ec7eb5a13372e3e80dc9a9fff1087
https://pubmed.ncbi.nlm.nih.gov/32254290
https://pubmed.ncbi.nlm.nih.gov/32254290
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26803 (2011)
Amongst all leukemias, Bcr-Abl positive chronic myelogenous leukemia (CML) confers resistance to native drug due to multi drug resistance and also resistance to p53 and fas ligand pathways. In the present study, we have investigated the efficacy of m
Externí odkaz:
https://doaj.org/article/b6187757090a457d887b269c34bf9879
Autor:
Sean D. Allen, Vikas Nandwana, Soo-Ryoon Ryoo, Evan A. Scott, Leo I. Gordon, Abhalaxmi Singh, Vinayak P. Dravid, Jonathan S. Rink, Tzu Hung Chen, C. Shad Thaxton
Publikováno v:
ACS nano. 13(9)
B-cell lymphoma cells depend upon cholesterol to maintain pro-proliferation and pro-survival signaling via the B-cell receptor. Targeted cholesterol depletion of lymphoma cells is an attractive therapeutic strategy. We report here high-density lipopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6990eb14eefd338aa136229257f5c4
https://pubmed.ncbi.nlm.nih.gov/31487458
https://pubmed.ncbi.nlm.nih.gov/31487458
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 110
Targeted cancer therapy facilitates localizing the action of chemotherapeutic drugs at the tumor site enhancing the therapeutic efficacy and reducing the side effects to the healthy cells. The homing property of mesenchymal stem cells (MSCs), towards
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8eff87e2ff58d37a0110b6f83723bd
https://pubmed.ncbi.nlm.nih.gov/32204010
https://pubmed.ncbi.nlm.nih.gov/32204010
Publikováno v:
Anti-cancer agents in medicinal chemistry. 20(11)
The panorama of cancer treatment has taken a considerable leap over the last decade with the advancement in the upcoming novel therapies combined with modern diagnostics. Nanotheranostics is an emerging science that holds tremendous potential as a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e473650a3f5e9fbc60eb74eac0522a37
https://pubmed.ncbi.nlm.nih.gov/31429694
https://pubmed.ncbi.nlm.nih.gov/31429694
Autor:
Sreeparna Chakraborty, Abhalaxmi Singh, Mark Maienschein-Cline, Amitabha Mukhopadhyay, Jalees Rehman, Asrar B. Malik
Publikováno v:
The Journal of Immunology. 206:112.18-112.18
Immune memory has been well-established in adaptive immunity but recent studies suggest a key for memory in innate immunity. However, the precise mechanisms and phenotypes of innate immune memory in macrophages remain poorly understood. Here, we stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b7837ea3777938b3011cd7f0490536e
https://doi.org/10.4049/jimmunol.206.supp.112.18
https://doi.org/10.4049/jimmunol.206.supp.112.18