Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Abel Tesfaye Anshabo"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Cyclin-dependent kinases (CDKs) are proteins pivotal to a wide range of cellular functions, most importantly cell division and transcription, and their dysregulations have been implicated as prominent drivers of tumorigenesis. Besides the well-establ
Externí odkaz:
https://doaj.org/article/8666fa134b1f41e9b152dac1a2665699
Publikováno v:
Archives of Pharmacy Practice, Vol 5, Iss 3, Pp 113-117 (2014)
Background: Prevalence of type II diabetes mellitus(T2DM) is substantially increasing in Ethiopia but there are no studies on its drug therapy. Objective: To assess drug therapy for T2DM and check association between fasting blood glucose levels wit
Externí odkaz:
https://doaj.org/article/99fba83420ad4b78aa5f7ced136823e7
Autor:
Abel Tesfaye Anshabo, Laychiluh Bantie, Sarah Diab, Jimma Lenjisa, Alemwork Kebede, Yi Long, Gary Heinemann, Jasmine Karanjia, Benjamin Noll, Sunita K. C. Basnet, Manjun Li, Robert Milne, Hugo Albrecht, Shudong Wang
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1113
Mutations in FMS-like tyrosine kinase 3 (FLT3) occur in approximately one-third of AML patients and are associated with a particularly poor prognosis. The most common mutation, FLT3-ITD, is a self-activating internal tandem duplication (ITD) in the F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb76e0b4e5a2ac45bd74644f460d73c1
https://hdl.handle.net/11541.2/31432
https://hdl.handle.net/11541.2/31432
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Cyclin-dependent kinases (CDKs) are proteins pivotal to a wide range of cellular functions, most importantly cell division and transcription, and their dysregulations have been implicated as prominent drivers of tumorigenesis. Besides the well-establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659349d40544aecd517ff8ba076b69df
https://hdl.handle.net/11541.2/147812
https://hdl.handle.net/11541.2/147812
Autor:
Dagmawit Awoke, Abel Tesfaye Anshabo, Sefinew Migbaru, Wondemagegnhu Tigeneh, Ephrem Engidawork
Publikováno v:
Pain Practice. 17:1023-1031
Background Pain is a highly prevalent and distressing symptom in patients with cancer but at the same time inadequately treated in many of these patients. The major reason for such imbalance is inappropriate pain assessment. To overcome such a barrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba483de14d595f5207d5e93bc9dddf6
https://doi.org/10.1111/papr.12557
https://doi.org/10.1111/papr.12557
Autor:
Neil Portman, Solomon Tadesse, Shudong Wang, C. Elizabeth Caldon, Abel Tesfaye Anshabo, Wayne D. Tilley, Elgene Lim
Publikováno v:
Drug discovery today. 25(2)
Cyclin-dependent kinase 2 (CDK2) plays a pivotal part in cell cycle regulation and is involved in a range of biological processes. CDK2 interacts with and phosphorylates proteins in pathways such as DNA damage, intracellular transport, protein degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cb909d2d99af6248b05fbf0ad59301
https://pubmed.ncbi.nlm.nih.gov/31839441
https://pubmed.ncbi.nlm.nih.gov/31839441
Autor:
Muhammed H. Rahaman, John D. Hayball, Theodosia Teo, Stephen Philip, Laychiluh B. Mekonnen, Shudong Wang, Yi Long, Man-jun Li, Preethi Eldi, Mingfeng Yu, Benjamin Noll, Gary K. Heinemann, Yuchao Yang, Abel Tesfaye Anshabo, Robert W. Milne, Sarah Diab
Publikováno v:
European Journal of Medicinal Chemistry. 214:113248
CDK8 regulates transcription either by phosphorylation of transcription factors or, as part of a four-subunit kinase module, through a reversible association of the kinase module with the Mediator complex, a highly conserved transcriptional coactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9410b245d422cfbe104b9416c59eb800
https://doi.org/10.1016/j.ejmech.2021.113248
https://doi.org/10.1016/j.ejmech.2021.113248
Autor:
Dawit Negusu, Wondemagegnhu Tigeneh, Sefinew Migbaru, Alemseged Ayele Asfaw, Ephrem Engidawork, Dagmawit Awoke, Atalay Mulu, Abel Tesfaye Anshabo
Publikováno v:
Journal of Pain and Symptom Management. 51:947-953
Cancer patients often face a variety of symptoms that impact their quality of life. The management of these symptoms is highly dependent on the accurate appraisal of their severity through the use of a standardized symptom assessment tool. The M. D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9942676fb1b2e5993d608a8225c075
https://doi.org/10.1016/j.jpainsymman.2015.12.333
https://doi.org/10.1016/j.jpainsymman.2015.12.333
Publikováno v:
Journal of pain and symptom management. 56(2)
Background Although cancer-related fatigue (CRF) is a highly prevalent and distressing symptom associated with cancer and its treatment, it is mostly underscreened, underassessed, and undertreated. The Brief Fatigue Inventory (BFI) is a reliable and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079cb98a47aaafd3978a04eec15276ad
https://pubmed.ncbi.nlm.nih.gov/29753101
https://pubmed.ncbi.nlm.nih.gov/29753101
Autor:
Muhammed H. Rahaman, Gary K. Heinemann, Hugo Albrecht, Saiful Islam, Robert W. Milne, Abel Tesfaye Anshabo, Shudong Wang, Yinghui Zhang
Publikováno v:
Cancer Research. 79:4427-4427
Treatment of breast cancer represents a major therapeutic challenge, and thus identification of new targeted therapy is of paramount importance. Anti-apoptotic proteins, BCL2 and MCL1, and oncoprotein c-MYC are implicated in evasion of apoptosis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b948a802b7fabee8313a82fe998394f
https://doi.org/10.1158/1538-7445.am2019-4427
https://doi.org/10.1158/1538-7445.am2019-4427