Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Abel Suárez-Fueyo"'
Autor:
Manuel J Del Rey, Regina Faré, Elena Izquierdo, Alicia Usategui, José L Rodríguez-Fernández, Abel Suárez-Fueyo, Juan D Cañete, José L Pablos
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99607 (2014)
Synovial fibroblasts (SF) undergo phenotypic changes in rheumatoid arthritis (RA) that contribute to inflammatory joint destruction. This study was undertaken to evaluate the clinical and functional significance of ectopic podoplanin (gp38) expressio
Externí odkaz:
https://doaj.org/article/ba51c98777ef494b92b02779dd306599
Autor:
Eri Katsuyama, Morgane Humbel, Abel Suarez-Fueyo, Abhigyan Satyam, Nobuya Yoshida, Vasileios C. Kyttaris, Maria G. Tsokos, George C. Tsokos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract CD38 has emerged as a potential therapeutic target for patients with systemic lupus erythematosus (SLE) but it is not known whether CD38 alters CD4+ T cell function. Using primary human T cells and CD38-sufficient and CD38-deficient Jurkat T
Externí odkaz:
https://doaj.org/article/d0cd238c69d947889a5549cbde81b514
Autor:
Kayaho Maeda, Abel Suárez-Fueyo, Michihito Kono, Nobuya Yoshida, Vasileios C. Kyttaris, George C. Tsokos
Publikováno v:
Arthritis Rheumatol
OBJECTIVE Glutaminase 1 (Gls1) is the first enzyme in glutaminolysis. The selective Gls1 inhibitor bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide (BPTES) suppresses Th17 development and ameliorates experimental autoimmune encephalomyeli
Autor:
Ninghai Wang, Pablo Engel, Elisa Ten Hacken, George C. Tsokos, Nicholas Chiorazzi, Abel Suárez-Fueyo, Shih-Shih Chen, Roland W. Herzog, Jan A. Burger, Burcu Yigit, Catherine J. Wu, Atul K. Bhan, Cox Terhorst, Eri Katsuyama
Publikováno v:
Cancer Immunology Research. 7:1485-1496
The tumor microenvironment in leukemia and solid tumors induces a shift of activated CD8+ cytotoxic T cells to an exhausted state, characterized by loss of proliferative capacity and impaired immunologic synapse formation. Efficient strategies and ta
Autor:
George C. Tsokos, Kamalpreet Nagpal, Abel Suárez-Fueyo, Nobuya Yoshida, Wen Liang Pan, Andrew P. Ferretti, Maria Tsokos
Publikováno v:
J Immunol
Protein phosphatase 2A (PP2A) composed of a scaffold subunit, a catalytic subunit, and multiple regulatory subunits is a ubiquitously expressed serine/threonine phosphatase. We have previously shown that the PP2A catalytic subunit is increased in T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4195b45d7046a6fcf83452963bf13e
https://europepmc.org/articles/PMC8026731/
https://europepmc.org/articles/PMC8026731/
Publikováno v:
Nature Reviews Nephrology. 13:329-343
Glomerulonephritis is traditionally considered to result from the invasion of the kidney by autoantibodies and immune complexes from the circulation or following their formation in situ, and by cells of the innate and the adaptive immune system. The
Publikováno v:
Critical Reviews in Immunology. 37:39-58
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease linked to profound defects in the function and phenotype of T lymphocytes. Here, we describe abnormal signaling pathways that have been documented in T cells from patients with SLE an
Autor:
Seung Ki Kwok, Peter H. Lapchak, Kayaho Maeda, Eri Katsuyama, George C. Tsokos, Maria Tsokos, Abel Suárez-Fueyo
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Hyaluronic acid (HA), a component of the extracellular matrix, is the ligand for CD44 and has been implicated in the pathogenesis of kidney inflammation in patients with systemic lupus erythematosus (SLE), but its direct role and mechanism of action
Autor:
Lama Mulki, Vasileios C. Kyttaris, Suzanne Krishfield, Shannan J. Ho Sui, Abel Suárez-Fueyo, Eri Katsuyama, Sean J. Bradley, Joon Yoon, George C. Tsokos, Ana V. Marin, Masayuki Mizui, Fabio Malavasi
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 112-123.e4 (2020)
Summary: Patients with systemic lupus erythematosus (SLE) suffer frequent infections that account for significant morbidity and mortality. T cell cytotoxic responses are decreased in patients with SLE, yet the responsible molecular events are largely
Autor:
Yemil Atisha-Fregoso, J. Antonio Avina-Zubieta, Francesca Barone, Thomas G. Benedek, Ayal Ben-Zvi, Sasha Bernatsky, Susan A. Boackle, Hendrika Bootsma, Rebecka L. Bourn, Simon J. Bowman, Ian N. Bruce, Jill P. Buyon, Nancy L. Carteron, Kevin S. Cashman, Eliza F. Chakravarty, Sarah K. Chen, Yuting Chin, Benjamin F. Chong, Ann E. Clarke, Hannah Cohen, Karen H. Costenbader, José C. Crispín, Mary K. Crow, Maria Dall'Era, Karina de Leeuw, Yun Deng, Rama Dey-Rao, Betty Diamond, Thomas Dörner, Cristina Drenkard, Alexandre Dumusc, Laura Durcan, Olga Dvorkina, Giordano Egiziano, Keith B. Elkon, John M. Esdaile, Benjamin A. Fisher, Carla M. Fox, Robert I. Fox, Deborah M. Friedman, Shu Man Fu, Felicia Gaskin, Ian Giles, Ellen M. Ginzler, Bevra Hannahs Hahn, John G. Hanly, James E. Hansen, Falk Hiepe, Andrea Hinojosa-Azaola, Bimba Hoyer, Jens Y. Humrich, Yiannis Ioannou, David Isenberg, Mariko L. Ishimori, Peter M. Izmirly, Judith A. James, Caroline A. Jefferies, Scott A. Jenks, Meenakshi Jolly, April M. Jorge, Cees G.M. Kallenberg, Diane L. Kamen, Mariana J. Kaplan, George A. Karpouzas, Maryann Kimoto, Kyriakos A. Kirou, Dwight H. Kono, Frans G.M. Kroese, Antonio La Cava, Christine H. Lee, Thomas J.A. Lehman, Lyndell L. Lim, S. Sam Lim, Irina Litvin, Yudong Liu, Christian Lood, Susan Manzi, Terry K. Means, Juan M. Mejia-Vilet, Christa Miliaresis, Eric Morand, Laurence Morel, Champa Nataraja, Sandra V. Navarra, Saba Nayar, Timothy B. Niewold, Tamara M. Nowling, Farzana Nuruzzaman, Jim C. Oates, Andrew Oberst, Nancy J. Olsen, Ben Parker, Michelle Petri, Colin K.L. Phoon, David S. Pisetsky, Chaim Putterman, Anne V. Quismorio, Francisco P. Quismorio, Anisur Rahman, Bruce C. Richardson, Gabriela Riemekasten, James T. Rosenbaum, Brad H. Rovin, Jorge Sánchez-Guerrero, Ignacio Sanz, Lisa R. Sammaritano, Winston Sequeira, Tarun S. Sharma, Nan Shen, Cailin Sibley, Animesh A. Sinha, Brandi E. Stevens, Ariel D. Stock, Abel Suárez-Fueyo, Sun-Sang J. Sung, Sarah F. Taber, Yuanjia Tang, Isabelle J.C. Thibau, Tito P. Torralba, Zahi Touma, Betty P. Tsao, George C. Tsokos, Murray B. Urowitz, Swamy Venuturupalli, Arjan Vissink, Daniel J. Wallace, Hongyang Wang, Michael M. Ward, Stacy Weinberg, Victoria P. Werth, Sterling G. West, Le Xion, Jinoos Yazdany, Edward Yelin, Xiang Yu, Yong-Rui Zou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a2edc44e0ea147359c7c8d675b3828d
https://doi.org/10.1016/b978-0-323-47927-1.00078-5
https://doi.org/10.1016/b978-0-323-47927-1.00078-5