Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Abel Jonckheer"'
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 80:239-245
We have inserted a tryptophan (F77W) in the core of the regulatory domain of cardiac troponin C (cNTnC), and previously determined the structure of this mutant with and without the cosolvent trifluoroethanol (TFE). Interestingly, the orientations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fabee61ea476de330420eeff3e39df5
https://doi.org/10.1002/prot.23198
https://doi.org/10.1002/prot.23198
Autor:
Abel Jonckheer, Ann Gils, Erik Ceresa, Yves Engelborghs, Paul Declerck, M. De Maeyer, Miet Peeters
Publikováno v:
Journal of Thrombosis and Haemostasis. 5:2105-2112
Summary. Background: Activated thrombin activatable fibrinolysis inhibitor (TAFIa) plays a pivotal role in fibrinolysis. TAFIa activity is regulated by a temperature-dependent instability. This instability has not only complicated the study of struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333115d7b337f435f36fdb53fafe7766
https://doi.org/10.1111/j.1538-7836.2007.02720.x
https://doi.org/10.1111/j.1538-7836.2007.02720.x
Autor:
Nina V. Visser, Yves Engelborghs, Anton J.W.G. Visser, Olaf Rolinsky, Marc De Maeyer, Abel Jonckheer, Jean-Marie Frère
Publikováno v:
Biophysical Journal. 100(3)
The fluorescence emission of the single tryptophan (W233) of the mutant protein DD carboxypeptidase from streptomyces is characterized by a red edge excitation shift (REES). This phenomenon is an indication for strongly reduced dynamics in the enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629ea80513d33084a0724c09feb974a4
Publikováno v:
Current proteinpeptide science. 9(5)
We discuss the dynamics of tryptophan rotamers in the context of the non-exponential fluorescence decay in proteins. The central question is: how does the ground-state conformational heterogeneity influence the time evolution of tryptophan fluorescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9f0fef601b7b5b30f1cc62908f9341
https://pubmed.ncbi.nlm.nih.gov/18855696
https://pubmed.ncbi.nlm.nih.gov/18855696
Publikováno v:
Biophysical Journal. 98:748a
Several NMR studies have shown that co-solvent trifluoroethanol (TFE) does not perturb the overall three-dimensional structure of proteins. We have inserted a single tryptophan (F77W) in the hydrophobic core of the N-domain of cardiac troponin C (cNT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ff70824801d554640c126af66f4ef2
https://doi.org/10.1016/j.bpj.2009.12.4099
https://doi.org/10.1016/j.bpj.2009.12.4099
Publikováno v:
Biophysical Journal. (6):1778-1786
The origin of the biexponential fluorescence decay of Trp in ribonuclease T1 under mildly destabilizing conditions, such as increased pH or temperature, or the presence of detergent, is still not understood. We have performed two extended replica-exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1387bd14dde2fc67309b0f331e4cd94d
Autor:
Jean-Marc Plesséria, Jean-Marie Zimmer, Abel Jonckheer, Kristel Van Laethem, Miguel E. Quiñones-Mateu, Marc De Maeyer, François Roman, Kris Covens, Jean-Claude Schmit, Anne-Mieke Vandamme, Jan Weber, Christine Lambert, Jean-Yves Servais, Ana C. Vazquez
Publikováno v:
ResearcherID
Summary: We observed an unusual glycine-to-glutamate substitution at protease (PR) residue position 48 (G48E) in an African patient infected with a subtype A1 HIV-1 strain failing a saquinavir-containing regimen. Phenotypic analysis of protease inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756135b8f05cb1284fb240cfbd6390b4
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000257168500004&KeyUID=WOS:000257168500004
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000257168500004&KeyUID=WOS:000257168500004
