Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Abel C.S. Chun"'
Autor:
Xianghong Wang, Dong-Yan Jin, Sai Wah Tsao, Yong Chuan Wong, Ming-Tat Ling, John M. Nicholls, Xin-Yuan Guan, Liang Hu, Wen Deng, Qi Wang, Abel C.S. Chun, Hiu Wing Cheung
Rev7p has been suggested to play an important role in regulating DNA damage response in yeast, and recently, the human homologue (i.e., MAD2B) has been identified, which shares significant homology to the mitotic checkpoint protein MAD2. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620d50eb49190cd30b811c107961499f
https://doi.org/10.1158/0008-5472.c.6494960.v1
https://doi.org/10.1158/0008-5472.c.6494960.v1
Autor:
Xianghong Wang, Dong-Yan Jin, Sai Wah Tsao, Yong Chuan Wong, Ming-Tat Ling, John M. Nicholls, Xin-Yuan Guan, Liang Hu, Wen Deng, Qi Wang, Abel C.S. Chun, Hiu Wing Cheung
Supplementary Figure 1 from Inactivation of Human MAD2B in Nasopharyngeal Carcinoma Cells Leads to Chemosensitization to DNA-Damaging Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae2cc0bbea718a5727a4254c59ecaec
https://doi.org/10.1158/0008-5472.22366031
https://doi.org/10.1158/0008-5472.22366031
Autor:
Xianghong Wang, Dong-Yan Jin, Sai Wah Tsao, Yong Chuan Wong, Ming-Tat Ling, John M. Nicholls, Xin-Yuan Guan, Liang Hu, Wen Deng, Qi Wang, Abel C.S. Chun, Hiu Wing Cheung
Supplementary Figure Legend from Inactivation of Human MAD2B in Nasopharyngeal Carcinoma Cells Leads to Chemosensitization to DNA-Damaging Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355951bba749d67b3024e8b397b367b6
https://doi.org/10.1158/0008-5472.22366028
https://doi.org/10.1158/0008-5472.22366028
Publikováno v:
Cell Cycle. 12:365-378
REV1 is a Y-family polymerase specialized for replicating across DNA lesions at the stalled replication folk. Due to the high error rate of REV1-dependent translesion DNA synthesis (TLS), tight regulation of REV1 activity is essential. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15de5c3fe1f4b886f40f8c1790520956
https://doi.org/10.4161/cc.23214
https://doi.org/10.4161/cc.23214
Autor:
Dong-Yan Jin, Abel C.S. Chun
Publikováno v:
Biochemical Society Transactions. 38:110-115
In response to DNA damage, TLS (translesion synthesis) allows replicative bypass of various DNA lesions, which stall normal replication. TLS is achieved by low-fidelity polymerases harbouring less stringent active sites. In humans, Y-family polymeras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624977b2ce9adccd9da552ca3ea11333
https://doi.org/10.1042/bst0380110
https://doi.org/10.1042/bst0380110
Autor:
Dong-Yan Jin, Abel C.S. Chun
Publikováno v:
Journal of Biological Chemistry. 278:37439-37450
p53 regulates a number of genes through transcriptional activation and repression. p53-dependent mitotic checkpoint has been described, but the underlying mechanism is still obscure. Here we examined the effect of p53 on the expression of a human mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9844b9d9baca2a6a11b78b0476bc057a
https://doi.org/10.1074/jbc.m307185200
https://doi.org/10.1074/jbc.m307185200
Autor:
Angela K. F. Lo, Yu Liu, Abel C.S. Chun, Dong-Yan Jin, Xianghong Wang, Sai Wah Tsao, Annie L.M. Cheung, Y.C. Wong
Publikováno v:
Carcinogenesis. 21:2293-2297
Nasopharyngeal carcinoma (NPC) occurs with a high incidence in many countries in south-eastern Asia. Chromosomal abnormalities have been commonly found in NPC, but the underlying mechanism is not well understood. We determined mitotic indices, the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6419f03efe2a3897f7f35598e11a62f5
https://doi.org/10.1093/carcin/21.12.2293
https://doi.org/10.1093/carcin/21.12.2293
Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation
Autor:
Abel C.S. Chun, Karen V. Kibler, Dong-Yan Jin, Yuan Zhou, Kuan-Teh Jeang, Yun-De Hou, Hsiang-Fu Kung, Hai-Lin Wang
Publikováno v:
The EMBO Journal. 19:729-740
Hepatitis C virus (HCV) is the major etiological agent of blood-borne non-A non-B hepatitis and a leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. HCV core protein is a multifunctional protein with regulatory functions in cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170e01341c1075783a2806390e8756c4
https://doi.org/10.1093/emboj/19.4.729
https://doi.org/10.1093/emboj/19.4.729
Autor:
John M. Nicholls, Xin Yuan Guan, Ming-Tat Ling, Wen Deng, Sai Wah Tsao, Liang Hu, Qi Wang, Dong-Yan Jin, Yong-Chuan Wong, Xianghong Wang, Abel C.S. Chun, Hiu Wing Cheung
Publikováno v:
Cancer research. 66(8)
Rev7p has been suggested to play an important role in regulating DNA damage response in yeast, and recently, the human homologue (i.e., MAD2B) has been identified, which shares significant homology to the mitotic checkpoint protein MAD2. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d788177c44e4df9d3fc8ea92da4859
https://pubmed.ncbi.nlm.nih.gov/16618761
https://pubmed.ncbi.nlm.nih.gov/16618761
Publikováno v:
The Journal of biological chemistry. 278(14)
The anaphase-promoting complex activated by CDC20 and CDH1 is a major ubiquitination system that controls the destruction of cell cycle regulators. Exactly how ubiquitination is regulated in time and space is incompletely understood. Here we report o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c142ca7caca1174e16a1379be664e6
https://pubmed.ncbi.nlm.nih.gov/12560341
https://pubmed.ncbi.nlm.nih.gov/12560341