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BRAF/MEK inhibitors use for pediatric gliomas; real world experience from a resource-limited country
Autor:
Dima Abu Laban, Abeer Alsharif, Maysa Al-Hussaini, Mouness Obeidat, Bayan Maraqa, Qasem Alzoubi, Awni Musharbash, Saad Jaddoua, Raed Ramlawi, Kawther Khaleifeh, Ahmad Kh. Ibrahimi, Nasim Sarhan, Eric Bouffet, Nisreen Amayiri
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMost pediatric low-grade-gliomas (LGG) and some high-grade-gliomas (HGG) have alterations in the RAS/MAPK pathway. Promising high tumor response rates were achieved using BRAF/MEK inhibitors, however data on their use in low-middle-income
Externí odkaz:
https://doaj.org/article/a23babfb377e407680f20d2e4d1da559