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of 4
pro vyhledávání: '"Abeer Al-Ghouleh"'
Autor:
Abeer Al-Ghouleh, Ramneek Johal, Inas K Sharquie, Mohammed Emara, Helen Harrington, Farouk Shakib, Amir M Ghaemmaghami
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33929 (2012)
Allergens are initiators of both innate and adaptive immune responses. They are recognised at the site of entry by epithelial and dendritic cells (DCs), both of which activate innate inflammatory circuits that can collectively induce Th2 immune respo
Externí odkaz:
https://doaj.org/article/f62075558dfd48d58b5477d8757a4dfc
Autor:
Abeer Al-Ghouleh, Mohamed Emara, Luisa Martinez-Pomares, Pierre-Joseph Royer, Paddy Tighe, Herb F. Sewell, Nick D. Jones, Chaoxing Yang, Farouk Shakib, Amir M. Ghaemmaghami
Publikováno v:
The Journal of Immunology. 185:1522-1531
The mannose receptor (MR) is a C-type lectin expressed by dendritic cells (DCs). We have investigated the ability of MR to recognize glycosylated allergens. Using a gene silencing strategy, we have specifically inhibited the expression of MR on human
An investigation into IgE-facilitated allergen recognition and presentation by human dendritic cells
Autor:
Kathryn L. Armour, Farouk Shakib, Abeer Al-Ghouleh, Patricia Fitton, Mike Clark, Inas K. Sharquie, Amir M. Ghaemmaghami, Herb F. Sewell
Publikováno v:
BMC Immunology
Background Allergen recognition by dendritic cells (DCs) is a key event in the allergic cascade leading to production of IgE antibodies. C-type lectins, such as the mannose receptor and DC-SIGN, were recently shown to play an important role in the up
Publikováno v:
The Journal of Immunology. 188:125.2-125.2
Allergens are initiators of both innate and adaptive immune responses. They are recognised at the site of entry by epithelial and dendritic cells (DCs), both of which activate innate inflammatory circuits that can collectively induce Th2 immune respo