Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Abed N. Azab"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1271 (2024)
Background: Accumulating evidence suggests that nuclear factor (NF)-κB is involved in the pathophysiology of mood disorders. Objectives and Methods: We conducted two experimental protocols in rats to investigate the effects of a selective NF-κB inh
Externí odkaz:
https://doaj.org/article/e3bf32a353a04f22ac7c208a69e12db3
Autor:
Ronen Arbel, Abed N. Azab, Mansi Oberoi, Enis Aboalhasan, Artyom Star, Khaled Elhaj, Fouad Khalil, Hilmi Alnsasra
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background and aim:Heart failure with preserved ejection fraction (HFpEF) is associated with an increased risk of heart failure (HF) hospitalizations and cardiovascular death (CVD). Both dapagliflozin and sacubitril–valsartan have recently shown co
Externí odkaz:
https://doaj.org/article/5bd4dca853454dafb8589ab17b1cfb56
Publikováno v:
Cells, Vol 13, Iss 10, p 801 (2024)
Stress is a common denominator of complex disorders and the FK-506 binding protein (FKBP)51 plays a central role in stress. Hence, it is not surprising that multiple studies imply the involvement of the FKBP51 protein and/or its coding gene, FKBP5, i
Externí odkaz:
https://doaj.org/article/906a5ed74b9d498e8df6f15ae9da36b0
Autor:
Hilmi Alnsasra, Gal Tsaban, Adam Solomon, Fouad Khalil, Enis Aboalhasan, Abed N. Azab, Joseph Azuri, Ariel Hammerman, Ronen Arbel
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and Aim: Dapagliflozin and empagliflozin have demonstrated favorable clinical outcomes among patients with chronic kidney disease (CKD). However, their comparative monetary value for improving outcomes in CKD patients is unestablished. We
Externí odkaz:
https://doaj.org/article/f239e2acc26241b6ac06ddf616508645
Publikováno v:
Psychiatry and Clinical Psychopharmacology, Vol 31, Iss 3, Pp 344-352 (2021)
Externí odkaz:
https://doaj.org/article/37efd4fd1f254c08af596ba510a4fd94
Autor:
Yehudit Bloch, R. H. Belmaker, Pesach Shvartzman, Pnina Romem, Arkady Bolotin, Yuly Bersudsky, Abed N. Azab
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Oxygen enriched air may increase oxygen pressure in brain tissue and have biochemical effects even in subjects without lung disease. Consistently, several studies demonstrated that normobaric oxygen treatment has clinical benefits in some ne
Externí odkaz:
https://doaj.org/article/0164be22763d4d4cbf2b01982a8dbe38
Autor:
Ira S. Rostevanov, Batya Betesh-Abay, Ahmad Nassar, Elina Rubin, Sarit Uzzan, Jacob Kaplanski, Linoy Biton, Abed N. Azab
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAccumulative data links inflammation and immune dysregulation to the pathophysiology of mental disorders; little is known regarding leukotrienes’ (LTs) involvement in this process. Circumstantial evidence suggests that treatment with leuk
Externí odkaz:
https://doaj.org/article/69708425003a4b3d91d1805979a2267f
Autor:
Ahmad Nassar, Abed N. Azab
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1063 (2022)
Several studies support the notion that inflammation plays a role in the pathophysiology and treatment approaches of psychiatric illnesses, particularly mood disorders. Congruently, classic anti-inflammatory drugs were found efficacious in randomized
Externí odkaz:
https://doaj.org/article/fe09ffc018664107b7acbd2c554de964
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 901 (2022)
Mounting evidence suggests that immune-system dysfunction and inflammation play a role in the pathophysiology and treatment of mood-disorders in general and of bipolar disorder in particular. The current study examined the effects of chronic low-dose
Externí odkaz:
https://doaj.org/article/253fc6d57eae4061ad49e31249a33a08
Autor:
Elina Rubin, Agnese C. Pippione, Matthew Boyko, Giacomo Einaudi, Stefano Sainas, Massimo Collino, Carlo Cifani, Marco L. Lolli, Naim Abu-Freha, Jacob Kaplanski, Donatella Boschi, Abed N. Azab
Publikováno v:
Brain Sciences, Vol 12, Iss 1, p 35 (2021)
Aim: Nuclear factor kappa B (NF-κB) is known to play an important role in the inflammatory process which takes place after ischemic stroke. The major objective of the present study was to examine the effects of MEDS-23, a potent inhibitor of NF-κB,
Externí odkaz:
https://doaj.org/article/620830c9d1f540aeba0455c3517c6158