Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Abeba Teshager"'
1
Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates
Autor: H. Shaw Warren, Nondita S. Malo, Omeed Moaven, José Luis Millán, Sonoko Narisawa, Richard A. Hodin, Brishti Biswas, Konstantinos P. Economopoulos, Simon C. Robson, Abeba Teshager, Sarah S. Gul, Sulaiman R. Hamarneh, Nur Muhammad, Elizabeth L. Hohmann, Mussa M. Rafat Mohamed, Sayeda Nasrin Alam, Qingsong Tao, Madhu S. Malo
Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 306:G826-G838
The intestinal microbiota plays a pivotal role in maintaining human health and well-being. Previously, we have shown that mice deficient in the brush-border enzyme intestinal alkaline phosphatase (IAP) suffer from dysbiosis and that oral IAP suppleme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf15279cacd572ce63734380eaafcd2
https://doi.org/10.1152/ajpgi.00357.2013
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2
Intestinal alkaline phosphatase inhibits the proinflammatory nucleotide uridine diphosphate
Autor: Madhu S. Malo, Elizabeth L. Hohmann, Richard A. Hodin, Halim Yammine, Kanakaraju Kaliannan, José Luis Millán, Omeed Moaven, Sayeda Nasrin Alam, Sundaram Ramasamy, Nur Muhammad, Angela K. Moss, H. Shaw Warren, Palak Patel, Abeba Teshager, Nondita S. Malo, Sulaiman R. Hamarneh, Sonoko Narisawa, Mussa M. Rafat Mohamed
Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 304:G597-G604
Uridine diphosphate (UDP) is a proinflammatory nucleotide implicated in inflammatory bowel disease. Intestinal alkaline phosphatase (IAP) is a gut mucosal defense factor capable of inhibiting intestinal inflammation. We used the malachite green assay
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14eb30143e4b6218eca93e56cd8318e5
https://doi.org/10.1152/ajpgi.00455.2012
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3
Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice
Autor: Qingsong Tao, Juan M. Ramirez, Kanakaraju Kaliannan, Michael Y. Choi, Richard A. Hodin, Abeba Teshager, Aaron Karas, Tyler J. Tantillo, Sara A. Morrison, Sarah S. Gul, Konstantinos P. Economopoulos, Byeong-Moo Kim, W. Liu, Dong Hu, Atul K. Bhan, Sulaiman R. Hamarneh, Mussa M. Rafat Mohamed, Madhu S. Malo
Publikováno v: Digestive diseases and sciences. 62(8)
Bacterially derived factors from the gut play a major role in the activation of inflammatory pathways in the liver and in the pathogenesis of alcoholic liver disease. The intestinal brush-border enzyme intestinal alkaline phosphatase (IAP) detoxifies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbe37f905d1e9200d2a234a07f7da47
https://pubmed.ncbi.nlm.nih.gov/28424943
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4
Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase
Autor: S. Hakimian, Rizwan Ahmed, Mussa M. Rafat Mohamed, Kanakaraju Kaliannan, Palak Patel, Omeed Moaven, Caleb D. Phillips, Konstantinos P. Economopoulos, Sayeda Nasrin Alam, Naomi L. Ward, Madhu S. Malo, J. F. Haller, Abeba Teshager, Stephen B. Cox, Richard A. Hodin, Atul K. Bhan, Allan M. Goldstein
Publikováno v: Diabetes, obesitymetabolism. 18(5)
Aims To examine whether co-administration of intestinal alkaline phosphatase (IAP) with antibiotics early in life may have a preventive role against metabolic syndrome (MetS) in mice. Methods A total of 50 mice were allocated to four treatment groups
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeeed5124b3f9b8e4eabec75a924c96a
https://pubmed.ncbi.nlm.nih.gov/26876427
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5
Intestinal alkaline phosphatase prevents metabolic syndrome in mice
Autor: Richard A. Hodin, Palak Patel, Nur Muhammad, Abeba Teshager, Rizwan Ahmed, Sonoko Narisawa, Elizabeth L. Hohmann, S. Hakimian, Omeed Moaven, Mussa M. Rafat Mohamed, Sayeda Nasrin Alam, Seyed Mahdi Abtahi, Kanakaraju Kaliannan, Angela K. Moss, Madhury Ray, Madhu S. Malo, Sulaiman R. Hamarneh, José Luis Millán, Atul K. Bhan, Nondita S. Malo, Atri Raychowdhury, Konstantinos P. Economopoulos, H. Shaw Warren
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 110(17)
Metabolic syndrome comprises a cluster of related disorders that includes obesity, glucose intolerance, insulin resistance, dyslipidemia, and fatty liver. Recently, gut-derived chronic endotoxemia has been identified as a primary mediator for trigger
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f74a0072b8470020aa315bcf9ed5aff
https://pubmed.ncbi.nlm.nih.gov/23609332
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