Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Abe E. Kasonga"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125145 (2015)
An unbalanced diet can have adverse effects on health. Long chain polyunsaturated fatty acids (LCPUFAs) have been the focus of research owing to their necessity of inclusion in a healthy diet. However, the effects of LCPUFAs on human osteoclast forma
Externí odkaz:
https://doaj.org/article/8dcb31237e574216841d97b44e6d381d
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10544, p 10544 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10544, p 10544 (2021)
Osteoclasts are large, multinucleated cells that are responsible for the resorption of bone. Bone degenerative diseases, such as osteoporosis, are characterized by overactive osteoclasts. Receptor activator of nuclear factor-κB (NF-κB) ligand (RANK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822db9de99e16765e608110d55fb28f3
https://pubmed.ncbi.nlm.nih.gov/34638884
https://pubmed.ncbi.nlm.nih.gov/34638884
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1864:281-289
Bone is a dynamic tissue that is constantly remodelled by bone resorbing osteoclasts and bone forming osteoblasts, respectively. A breakdown in the remodelling process underlies several bone diseases such as osteoporosis. Unsaturated fatty acids (UFA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c56eef684a9dced245d41828abf69d9
https://doi.org/10.1016/j.bbalip.2018.12.009
https://doi.org/10.1016/j.bbalip.2018.12.009
Autor:
Marlena C. Kruger, Travers Sagar, Martina Rauner, Magdalena Coetzee, Sumari Marais, Shaakirah Moosa, Ulrike Baschant, Abe E. Kasonga
Publikováno v:
Journal of Functional Foods, Vol 64, Iss, Pp 103616-(2020)
Bone remodelling in a healthy body is in constant balance, maintaining an adaptive and robust skeletal system. In osteoporosis this balance is disrupted with the rates of osteoclastic bone resorption exceeding osteoblastic bone formation, resulting i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cfc6a45c12ae06b235f56110c15e8c
http://www.sciencedirect.com/science/article/pii/S1756464619305407
http://www.sciencedirect.com/science/article/pii/S1756464619305407
Autor:
Magdalena Coetzee, Xiao Xing Stander, Vishwa Deepak, Abe E. Kasonga, Dwayne Koot, Andre Stander, Binglin Wang
Publikováno v:
Chemical Biology & Drug Design. 90:97-111
The bromodomain (BRD) and extra-terminal domain (BET) protein family bind to acetylated histones on lysine residues and act as epigenetic readers. Recently, the role of this protein family in bone loss has been gaining attention. Earlier studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc79a98ee7b8492372e40f4f770ab4a
https://doi.org/10.1111/cbdd.12930
https://doi.org/10.1111/cbdd.12930
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1798 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 7
International Journal of Molecular Sciences
Volume 20
Issue 7
Osteoclasts are the sole bone resorbing cell in the body and their over activity is key in the development of osteoporosis. Osteoclastogenesis is mediated by receptor activator of nuclear factor &kappa
B ligand (RANKL) signalling pathways. Unsat
B ligand (RANKL) signalling pathways. Unsat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a26f99128ee15dabbf479be1009af1
https://www.mdpi.com/1422-0067/20/7/1798
https://www.mdpi.com/1422-0067/20/7/1798
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:1150-1158
Bone is a dynamic tissue that undergoes continuous remodeling coupled with the action of osteoblasts and osteoclasts. Osteoclast activity is elevated during osteoporosis and periodontitis resulting in excessive loss of trabecular and alveolar bone. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d680ddef5f8334999fbe85e8b5057ae
https://doi.org/10.1248/bpb.b16-00117
https://doi.org/10.1248/bpb.b16-00117
Autor:
Marlena C. Kruger, Sumari Marais, Megan Jean Bester, Magdalena Coetzee, Innocentia Botlhale Magoshi, Abe E. Kasonga, Shaakirah Moosa, Vishwa Deepak
Publikováno v:
Foodfunction. 9(6)
Rooibos tea is a naturally sweet and aromatic tea that is native to the Western Cape province of South Africa. Rooibos is usually fermented to produce the traditional reddish brown colour and has been found to have numerous health benefits. These inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0241a7ddd81ca85fb7bd29d8ca6dcf46
https://pubmed.ncbi.nlm.nih.gov/29790498
https://pubmed.ncbi.nlm.nih.gov/29790498
Autor:
Miki Tadaishi, Abe E. Kasonga, Marlena C. Kruger, Yoshiko Ishimi, Magdalena Coetzee, Yuko Tousen, Shin-ichi Katsumata, Vishwa Deepak
Publikováno v:
Journal of Nutritional Science and Vitaminology. 61:S142-S144
New Zealand is a rich source of food components that may have bioactivity on bone. Docosahexaenoic acid (DHA) from fish oil has been shown to maintain bone in ovariectomised (OVX) rats. Kiwifruit, a source of fibre and carotenoids, may also affect bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe191050b238c3514d68d327cd738080
https://doi.org/10.3177/jnsv.61.s142
https://doi.org/10.3177/jnsv.61.s142
Autor:
Magdalena Coetzee, Sumari Marais, Marlena C. Kruger, Vishwa Deepak, Abe E. Kasonga, Shaakirah Moosa
Publikováno v:
Bone Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b9302e3ed394b013bd0915350a45de
https://doi.org/10.1530/boneabs.5.p172
https://doi.org/10.1530/boneabs.5.p172