Výsledky vyhledávání - "Abdulwahed Alrehaily"

Akademický článek

Novel sofosbuvir derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective

Autor: Abdulwahed Alrehaily, Abdo A. Elfiky, Ibrahim M. Ibrahim, Mohamed N. Ibrahim, Amr Sonousi

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract The human coronavirus, SARS-CoV-2, had a negative impact on both the economy and human health, and the emerging resistant variants are an ongoing threat. One essential protein to target to prevent virus replication is the viral RNA-dependent

Externí odkaz: https://doaj.org/article/5a0651a77deb42aa9ce6637070bdcc73

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Akademický článek

Synthesis, molecular docking, in silico study, and evaluation of bis-thiazole-based curcumin derivatives as potential antimicrobial agents

Autor: Sobhi M. Gomha, Abdel-Aziz A.A. El-Sayed, Abdulwahed Alrehaily, Hossein M. Elbadawy, Basant Farag, Ahmad A. Al-Shahri, Saleh R. Alsenani, Fathy E. Abdelgawad, Magdi E.A. Zaki

Publikováno v: Results in Chemistry, Vol 7, Iss , Pp 101504- (2024)

The escalating challenge of antibiotic resistance, responsible for nearly a fifth of global fatalities, underscores the critical need for innovative therapeutic approaches and the creation of new medicinal and diagnostic solutions. Thiosemicarbazones

Externí odkaz: https://doaj.org/article/5bd5626053fd4402b63736b3c845a8d2

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Akademický článek

Pseudomonas putida Metallothionein: Structural Analysis and Implications of Sustainable Heavy Metal Detoxification in Madinah

Autor: Munazzah Tasleem, Abdel-Aziz A. A. El-Sayed, Wesam M. Hussein, Abdulwahed Alrehaily

Publikováno v: Toxics, Vol 11, Iss 10, p 864 (2023)

Heavy metals, specifically cadmium (Cd) and lead (Pb), contaminating water bodies of Madinah (Saudi Arabia), is a significant environmental concern that necessitates prompt action. Madinah is exposed to toxic metals from multiple sources, such as tob

Externí odkaz: https://doaj.org/article/b6baaea1915a446788c501d1aa5abf5f

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Akademický článek

Investigation of Antidepressant Properties of Yohimbine by Employing Structure-Based Computational Assessments

Autor: Munazzah Tasleem, Abdulwahed Alrehaily, Tahani M. Almeleebia, Mohammad Y. Alshahrani, Irfan Ahmad, Mohammed Asiri, Nadiyah M. Alabdallah, Mohd Saeed

Publikováno v: Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 1805-1827 (2021)

The use of pharmaceuticals to treat Major Depressive Disorder (MDD) has several drawbacks, including severe side effects. Natural compounds with great efficacy and few side effects are in high demand due to the global rise in MDD and ineffective trea

Externí odkaz: https://doaj.org/article/69ca12e42b4141e88f44326246cb300b

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Akademický článek

An In Silico Bioremediation Study to Identify Essential Residues of Metallothionein Enhancing the Bioaccumulation of Heavy Metals in Pseudomonas aeruginosa

Autor: Munazzah Tasleem, Wesam M. Hussein, Abdel-Aziz A. A. El-Sayed, Abdulwahed Alrehaily

Publikováno v: Microorganisms, Vol 11, Iss 9, p 2262 (2023)

Microorganisms are ubiquitously present in the environment and exert significant influence on numerous natural phenomena. The soil and groundwater systems, precipitation, and effluent outfalls from factories, refineries, and waste treatment facilitie

Externí odkaz: https://doaj.org/article/a193b78fca604cc7bcafadb5fdb894e3

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Bioremediation of Chromium-Contaminated Groundwater Using Chromate Reductase from Pseudomonas putida: An In Silico Approach

Autor: Munazzah Tasleem, Abdel-Aziz A. A. El-Sayed, Wesam Mekawy Hussein, Abdulwahed Alrehaily

Publikováno v: Water; Volume 15; Issue 1; Pages: 150

Chromium is a toxic heavy metal abundantly present in the environment, specifically in groundwater. The groundwater in Saudi Arabia was assessed for heavy metal presence; chromium was detected at a high concentration in Madinah. Many researchers have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8270901c719fe739c629352521992c83

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Computational analysis of PTP-1B site-directed mutations and their structural binding to potential inhibitors

Autor: null Munazzah Tasleem, null Ambreen Shoaib, null Asma Al-Shammary, null Abdelmuhsin Abdelgadir, null Zeina Alsamar, null Qazi Mohammad Sajid Jamal, null Abdulwahed Alrehaily, null Fevzi Bardcki, null Abdel Moneim E. Sulieman, null Tarun Kumar Upadhyay, null Irfan Ahmad Ansari, null Dakun Lai, null Riadh Badroui, null Dharmendra Kumar Yadav, null Mohd Saeed

Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 68(7)

Protein tyrosine phosphatase-1B (PTP-1B) is a well-known therapeutic target for diabetes and obesity as it suppresses insulin and leptin signaling. PTP-1B deletion or pharmacological suppression boosted glucose homeostasis and insulin signaling witho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6bc2380317a6b4f37b7e99b2c3f88f
https://pubmed.ncbi.nlm.nih.gov/36495515

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Investigation of Antidepressant Properties of Yohimbine by Employing Structure-Based Computational Assessments

Autor: Nadiyah M. Alabdallah, Tahani M. Almeleebia, Irfan Ahmad, Munazzah Tasleem, Abdulwahed Alrehaily, Mohammed Asiri, Mohd Saeed, Mohammad Y. Alshahrani

Publikováno v: Current Issues in Molecular Biology
Volume 43
Issue 3
Pages 127-1827
Current Issues in Molecular Biology, Vol 43, Iss 127, Pp 1805-1827 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32294abbea874d976f7f07258673dc2b

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