Výsledky vyhledávání - "Abdulwahab J. Al-Tourah"

Comparison of real-world treatment patterns in chronic lymphocytic leukemia management before and after availability of ibrutinib in the province of British Columbia, Canada

Autor: Alina S. Gerrie, Monica Hrynchak, Tracy Tucker, Cynthia L. Toze, Sean D. Young, Peter Tsang, Abdulwahab J. Al Tourah, Laurie H. Sehn, Gregory Dueck, Edward Hardy, Paul F. Galbraith, Helene Bruyere, Michael C. Noble, Steven J.T. Huang, Khaled M. Ramadan

Publikováno v: Leukemia research. 91

We performed a retrospective study comparing treatment patterns and overall survival (OS) in chronic lymphocytic leukemia (CLL) patients with the advent of ibrutinib to provide current real-world data.Using a provincial population-based database, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b433e82562e657a5441aabe1bb99adfe
https://pubmed.ncbi.nlm.nih.gov/32114372

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Impact of age and treatment institution type on outcomes of patients treated for chronic lymphocytic leukemia in British Columbia, Canada

Autor: Alina S. Gerrie, Tracy Tucker, Edward Hardy, Monica Hrynchak, Steven J.T. Huang, Abdulwahab J. Al Tourah, Michael C. Noble, Gregory Dueck, Helene Bruyere, Sean D. Young, Khaled M. Ramadan, Paul F. Galbraith, Laurie H. Sehn, Peter Tsang, Cynthia L. Toze

Publikováno v: Leukemia Research. 103:106538

Older age has been shown to adversely impact overall survival (OS) in chronic lymphocytic leukemia (CLL) however, prior population-based studies did not analyze the impact of cytogenetic abnormalities or were prior to the availability of ibrutinib.i)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f32a1f2ddd338c427918a4d523f3b7b
https://doi.org/10.1016/j.leukres.2021.106538

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Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group

Autor: Michael Crump, Elizabeth Eisenhauer, Rena Buckstein, John Kuruvilla, Wendy Walsh, David MacDonald, Alison Foo, Neil Chua, S. Percy Ivy, Christina R. Lee, Abdulwahab J Al-Tourah

Publikováno v: Leukemia & Lymphoma

There are limited effective therapies for most patients with relapsed diffuse large B-cell lymphoma (DLBCL). We conducted a phase II trial of the multi-targeted vascular endothelial growth factor receptor (VEGFR) kinase inhibitor, sunitinib, 37.5 mg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f6b86f1b6e42318b12922b7956c4c3
https://doi.org/10.3109/10428194.2011.555892

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Allogeneic SCT for relapsed composite and transformed lymphoma using related and unrelated donors: long-term results

Autor: Abdulwahab J. Al-Tourah, Donna L. Forrest, Jean M. Connors, Khaled M. Ramadan, Donna E. Hogge, Stephen H. Nantel, Clayton A. Smith, Cynthia L. Toze, Yasser Abou-Mourad, N. J. Voss, Randy D. Gascoyne, Mukesh Chhanabhai, Heather J. Sutherland, Kevin W. Song, Michael J. Barnett, Ryan R. Brinkman, J D Shepherd, Julye C. Lavoie, Thomas J. Nevill

Publikováno v: Bone Marrow Transplantation. 42:601-608

Outcome is poor with conventional therapy for relapsed transformed non-Hodgkin's lymphoma (NHL). Autologous SCT has been successfully employed; however the impact of allogeneic SCT has not been well defined. We therefore studied 40 consecutive patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a927e22aadbfc18e3ea0865ab94c05
https://doi.org/10.1038/bmt.2008.220

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Autologous and allogeneic stem-cell transplantation for transformed follicular lymphoma: a report of the Canadian blood and marrow transplant group

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 31(9)

Purpose To determine whether autologous (auto) or allogeneic (allo) stem-cell transplantation (SCT) improves outcome in patients with transformed follicular lymphoma compared with rituximab-containing chemotherapy alone. Patients and Methods This was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88989cfc10e395598ff35d1bd16e2a5f
https://pubmed.ncbi.nlm.nih.gov/23401459

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The architectural pattern of FOXP3-positive T cells in follicular lymphoma is an independent predictor of survival and histologic transformation

Autor: Pedro Farinha, Randy D. Gascoyne, Karamjit Gill, Abdulwahab J. Al-Tourah, Joseph M. Connors, Richard Klasa

Publikováno v: Blood. 115(2)

Previous studies of follicular lymphoma (FL) patients treated heterogeneously have suggested that decreased numbers of regulatory T cells correlates with improved survival. We studied advanced-stage FL patients from a single institution phase 2 trial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f49a294f35f75b64e6f63575f40c40
https://pubmed.ncbi.nlm.nih.gov/19901260

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Population-based analysis of incidence and outcome of transformed non-Hodgkin's lymphoma

Autor: Richard Klasa, Karamjit Gill, Mukesh Chhanabhai, Laurie H. Sehn, Joseph M. Connors, Tamara Shenkier, Randy D. Gascoyne, Kerry J. Savage, Paul Hoskins, Abdulwahab J. Al-Tourah

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(32)

Purpose To assess the incidence and predictive factors for development of transformed lymphoma in a population-based series of patients with follicular lymphoma (FL). Patients and Methods The Lymphoid Cancer Database was used to identify patients wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e5cf1317c428eb9bc025b3e8246fe7
https://pubmed.ncbi.nlm.nih.gov/18838711

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Genome-wide profiling of follicular lymphoma by array comparative genomic hybridization reveals prognostically significant DNA copy number imbalances

Autor: Adele Telenius, Joseph M. Connors, Abdulwahab J. Al-Tourah, Thomas Relander, Douglas E. Horsman, Randy D. Gascoyne, Nathalie A. Johnson, Raymond T. Ng, Wan L. Lam, Sohrab P. Shah, K-John Cheung, Betty Lai, Kevin Murphy, Christian Steidl

Publikováno v: Blood. 113(1)

The secondary genetic events associated with follicular lymphoma (FL) progression are not well defined. We applied genome-wide BAC array comparative genomic hybridization to 106 diagnostic biopsies of FL to characterize regional genomic imbalances. U

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c12747f3c48d5a2a05bd934cd9b0321
https://pubmed.ncbi.nlm.nih.gov/18703704

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Minimizing treatment without compromising cure with primary surveillance for clinical stage I embryonal predominant nonseminomatous testicular cancer: a population based analysis from British Columbia

Autor: Chris Coppin, Christian Kollmannsberger, Ada Man, Kim N. Chi, Abdulwahab J. Al-Tourah, Nevin Murray

Publikováno v: The Journal of urology. 174(6)

We evaluated the outcome of patients with embryonal carcinoma predominant (ECP) clinical stage (CS) I nonseminomatous testicular germ cell tumors (NSGCT) treated with primary surveillance or primary retroperitoneal lymph node dissection (RPLND).This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8450f001df4626c0143682f1fe18bf7c
https://pubmed.ncbi.nlm.nih.gov/16280765

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