Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Abdulshakour, Mohammadnia"'
Autor:
Florian Pernin, Qiao-Ling Cui, Abdulshakour Mohammadnia, Milton G. F. Fernandes, Jeffery A. Hall, Myriam Srour, Roy W. R. Dudley, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Hannah E. Salapa, Michael C. Levin, G. R. Wayne Moore, Timothy E. Kennedy, Christine Vande Velde, Jack P. Antel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Oligodendrocyte (OL) injury and subsequent loss is a pathologic hallmark of multiple sclerosis (MS). Stress granules (SGs) are membrane-less organelles containing mRNAs stalled in translation and considered as participants of the cellular re
Externí odkaz:
https://doaj.org/article/7ecd4f332096485d86164c4aeb9e24fc
Autor:
Milton Guilherme Forestieri Fernandes, Abdulshakour Mohammadnia, Florian Pernin, Laura Eleonora Schmitz-Gielsdorf, Caroline Hodgins, Qiao-Ling Cui, Moein Yaqubi, Manon Blain, Jeffery Hall, Roy Dudley, Myriam Srour, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Jo Anne Stratton, Moses Rodriguez, Tanja Kuhlmann, Wayne Moore, Timothy E. Kennedy, Jack P. Antel
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Oligodendrocyte (OL) injury and loss are central features of evolving lesions in multiple sclerosis. Potential causative mechanisms of OL loss include metabolic stress within the lesion microenvironment. Here we use the injury response of pr
Externí odkaz:
https://doaj.org/article/0b83309164e245e4aea64f44e59886dc
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Single cell analysis of cancer cell transcriptome may shed a completely new light on cancer-associated thrombosis (CAT). CAT causes morbid, and sometimes lethal complications in certain human cancers known to be associated with high risk of venous th
Externí odkaz:
https://doaj.org/article/7b3c981db554434bb2aead2861c5b7e1
Autor:
Ashot S. Harutyunyan, Brian Krug, Haifen Chen, Simon Papillon-Cavanagh, Michele Zeinieh, Nicolas De Jay, Shriya Deshmukh, Carol C. L. Chen, Jad Belle, Leonie G. Mikael, Dylan M. Marchione, Rui Li, Hamid Nikbakht, Bo Hu, Gael Cagnone, Warren A. Cheung, Abdulshakour Mohammadnia, Denise Bechet, Damien Faury, Melissa K McConechy, Manav Pathania, Siddhant U. Jain, Benjamin Ellezam, Alexander G. Weil, Alexandre Montpetit, Paolo Salomoni, Tomi Pastinen, Chao Lu, Peter W. Lewis, Benjamin A. Garcia, Claudia L. Kleinman, Nada Jabado, Jacek Majewski
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Lysine27-to-methionine mutations in histone H3 genes (H3K27M) occur in a subgroup of gliomas and decrease genome-wide H3K27 trimethylation. Here the authors utilise primary H3K27M tumour lines and isogenic CRISPR-edited controls and show that H3K27M
Externí odkaz:
https://doaj.org/article/0beae741fed94f66b31dab929cbfe1ba
Autor:
Selin Jessa, Abdulshakour Mohammadnia, Ashot S. Harutyunyan, Maud Hulswit, Srinidhi Varadharajan, Hussein Lakkis, Nisha Kabir, Zahedeh Bashardanesh, Steven Hébert, Damien Faury, Maria C. Vladoiu, Samantha Worme, Marie Coutelier, Brian Krug, Augusto Faria Andrade, Manav Pathania, Andrea Bajic, Alexander G. Weil, Benjamin Ellezam, Jeffrey Atkinson, Roy W. R. Dudley, Jean-Pierre Farmer, Sebastien Perreault, Benjamin A. Garcia, Valérie Larouche, Mathieu Blanchette, Livia Garzia, Aparna Bhaduri, Keith L. Ligon, Pratiti Bandopadhayay, Michael D. Taylor, Stephen C. Mack, Nada Jabado, Claudia L. Kleinman
Publikováno v:
Nat Genet
Canonical (H3.1/H3.2) and noncanonical (H3.3) histone 3 K27M-mutant gliomas have unique spatiotemporal distributions, partner alterations, and molecular profiles. The contribution of the cell-of-origin to these differences has been challenging to unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677717c5bfd30e952f67509fa7d12501
https://europepmc.org/articles/PMC9742294/
https://europepmc.org/articles/PMC9742294/
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167081 (2016)
Direct reprogramming using defined sets of transcription factors (TFs) is a recent strategy for generating induced hepatocytes (iHeps) from fibroblasts for use in regenerative medicine and drug development. Comprehensive studies detailing the regulat
Externí odkaz:
https://doaj.org/article/12e94b6ca6314a4a88fd659012469e3a
Autor:
Niusha Khazaie, Mohammad Massumi, Ping Wee, Mahdieh Salimi, Abdulshakour Mohammadnia, Moein Yaqubi
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150518 (2016)
Induced pluripotent stem cells (iPSCs) provide a reliable source for the study of regenerative medicine, drug discovery, and developmental biology. Despite extensive studies on the reprogramming of mouse and human fibroblasts into iPSCs, the efficien
Externí odkaz:
https://doaj.org/article/24578237421a4d6c9b3ac948c88f3c17
Autor:
Brian Meehan, Dong-Sic Choi, Nadim Tawil, Rayhaan Bassawon, Janusz Rak, Ali Nehme, Cristiana Spinelli, Lata Adnani, Abdulshakour Mohammadnia, Kevin Petrecca, Laura Montermini, Charles P. Couturier
Publikováno v:
Neuro Oncol
BACKGROUND Vascular anomalies, including thrombosis, are a hallmark of glioblastoma (GBM) and an aftermath of dysregulated cancer cell genome and epigenome. Up-regulation of podoplanin (PDPN) by cancer cells has recently been linked to an increased r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522ad7ea32e7cc9d9be1c5e06e9a3cca
https://europepmc.org/articles/PMC8598477/
https://europepmc.org/articles/PMC8598477/
Autor:
Erfan Sharifi, Niusha Khazaei, Nicholas W. Kieran, Sahel Jahangiri Esfahani, Abdulshakour Mohammadnia, Moein Yaqubi
Publikováno v:
Gene. 812
Stem cell differentiation towards various somatic cells and body organs has proven to be an effective technique in the understanding and progression of regenerative medicine. Despite the advances made, concerns regarding the low efficiency of differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825804ce5358837fdff50b48da62fb1f
https://pubmed.ncbi.nlm.nih.gov/34902512
https://pubmed.ncbi.nlm.nih.gov/34902512
Autor:
Abdulshakour Mohammadnia, Hadi Hashemi, Sahel Jahangiri Esfahani, Moein Yaqubi, Mohammad Reza Omrani, Erfan Sharifi, Nicholas W. Kieran, Niusha Khazaei
Acquiring a specific transcriptomic signature of the human and mouse cardiomyocyte (CM) will greatly increase our understanding of their biology and associated diseases that remain the most deadly across the world. In this study, using comprehensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7504d38a1e7e36b3eb2a298687564723
https://doi.org/10.1101/2020.06.14.151399
https://doi.org/10.1101/2020.06.14.151399