Výsledky vyhledávání - "Abdulrahman A. Al-Majed"

Akademický článek

Theoretical study of the antioxidant mechanism and structure-activity relationships of 1,3,4-oxadiazol-2-ylthieno[2,3-d]pyrimidin-4-amine derivatives: a computational approach

Autor: Ahmed H. Bakheit, Tanveer A. Wani, Abdulrahman A. Al-Majed, Hamad M. Alkahtani, Manal M. Alanazi, Fahad Rubayyi Alqahtani, Seema Zargar

Publikováno v: Frontiers in Chemistry, Vol 12 (2024)

A theoretical thermodynamic study was conducted to investigate the antioxidant activity and mechanism of 1,3,4-oxadiazol-2-ylthieno[2,3-d]pyrimidin-4-amine derivatives (OTP) using a Density Functional Theory (DFT) approach. The study assessed how sol

Externí odkaz: https://doaj.org/article/bb2e40c580bf4c75b7e0824bbdccf355

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Akademický článek

Thermodynamic and Computational (DFT) Study of Non-Covalent Interaction Mechanisms of Charge Transfer Complex of Linagliptin with 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and Chloranilic acid (CHA)

Autor: Ahmed H. Bakheit, Rashad Al-Salahi, Abdulrahman A. Al-Majed

Publikováno v: Molecules, Vol 27, Iss 19, p 6320 (2022)

This study describes the non-covalent interactions of the charge transfer complex (CT), which was responsible for the synthesis of Linagliptin (LNG) with 2,3-Dichloro-5,6-Dicyano-1,4-benzoquinone (DDQ), or with Chloranilic acid (CHA) complexes in ace

Externí odkaz: https://doaj.org/article/c7f00fc69fb04456905061d2933c4765

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Akademický článek

Influence of Rutin, Sinapic Acid, and Naringenin on Binding of Tyrosine Kinase Inhibitor Erlotinib to Bovine Serum Albumin Using Analytical Techniques Along with Computational Approach

Autor: Tanveer A. Wani, Ahmed H. Bakheit, Seema Zargar, Arwa Ishaq A. Khayyat, Abdulrahman A. Al-Majed

Publikováno v: Applied Sciences, Vol 12, Iss 7, p 3575 (2022)

Flavonoid-containing food supplements are widely used as antioxidants, and the continuous use of these supplements with other drugs can lead to clinically significant interactions between these and other drugs. The medications in systemic circulation

Externí odkaz: https://doaj.org/article/9bba642d3e524bc29fa5fb7fe3a771a3

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Akademický článek

A Stability-Indicating HPLC-DAD Method for Determination of Stiripentol: Development, Validation, Kinetics, Structure Elucidation and Application to Commercial Dosage Form

Autor: Hany W. Darwish, Ali S. Abdelhameed, Mohamed I. Attia, Ahmed H. Bakheit, Nasr Y. Khalil, Abdulrahman A. Al-Majed

Publikováno v: Journal of Analytical Methods in Chemistry, Vol 2014 (2014)

A rapid, simple, sensitive, and accurate isocratic reversed-phase stability-indicating high performance liquid chromatography method has been developed and validated for the determination of stiripentol and its degradation product in its bulk form an

Externí odkaz: https://doaj.org/article/85fa49ffac2143edb1b93500212170b2

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Preface

Autor: Abdulrahman A. Al-Majed

Publikováno v: Profiles of Drug Substances, Excipients and Related Methodology ISBN: 9780443193828

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55e56751a36c2813bdd79c0ab7c9f717
https://doi.org/10.1016/s1871-5125(23)00009-2

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Full spectrum and genetic algorithm-selected spectrum-based chemometric methods for simultaneous determination of azilsartan medoxomil, chlorthalidone, and azilsartan: Development, validation, and application on commercial dosage form

Autor: Abdulrahman A. Al Majed, Ahmed H. Bakheit, Ibrahim A. Darwish, Ibrahim A. Al-Suwaidan, Hany W. Darwish, Hassan Alshehri

Publikováno v: Open Chemistry, Vol 19, Iss 1, Pp 205-213 (2021)

Five various chemometric methods were established for the simultaneous determination of azilsartan medoxomil (AZM) and chlorthalidone in the presence of azilsartan which is the core impurity of AZM. The full spectrum-based chemometric techniques, nam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c49068f313bf0854a417cfa413f921
https://doi.org/10.1515/chem-2021-0022

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Lodenafil

Autor: Yahya M, Alshehri, Abdulrahman A, Al-Majed, Mohamed W, Attwa, Ahmed H, Bakheit

Publikováno v: Profiles of drug substances, excipients, and related methodology. 47

Lodenafil is a class of drugs called an inhibitor of PDE5 which also include a wide range of other erectile medicines, such as sildenafil, tadalafil and vardenafil. It is part of a new generation of PDE5 inhibitors that includes udenafil and avanafil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::635a992af835cc9258416d0e69fd8cf7
https://pubmed.ncbi.nlm.nih.gov/35396013

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Binding and drug displacement study of colchicine and bovine serum albumin in presence of azithromycin using multispectroscopic techniques and molecular dynamic simulation

Autor: Anwar Baquaysh, Ahmed H. Bakheit, Tanveer A. Wani, Ashwaq Aljuraisy, Seema Zargar, Nojood Altwaijry, Abdulrahman A. Al-Majed

Publikováno v: Journal of Molecular Liquids

The binding and displacement interaction of colchicine and azithromycin to the model transport protein bovine serum albumin (BSA) was evaluated in this study. Azithromycin, a macrolide antibiotic, has antiviral properties and hence, has been used con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ca58b4f172b986130bfa63351a0cdd
https://pubmed.ncbi.nlm.nih.gov/33753950

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