Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Abdulmohsen I. Algefare"'
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 128-134 (2024)
Carbon tetrachloride (CCl4) is a classic chemical hepatotoxicant that triggers liver damage through hepatic exacerbation of oxidative stress. Geraniol (GRL) is a natural bioactive acyclic monoterpene with several pharmacological effects. We thus expl
Externí odkaz:
https://doaj.org/article/34a599afa1084abea545fd4afe409de6
Autor:
Osama Y. Althunibat, Mohammad H. Abukhalil, Muthana M. Jghef, Manal A. Alfwuaires, Abdulmohsen I. Algefare, Bader Alsuwayt, Reem Alazragi, Mohammed A. S. Abourehab, Afaf F. Almuqati, Shaik Karimulla, Saleem H. Aladaileh
Publikováno v:
Biomolecules & Biomedicine, Vol 23, Iss 4 (2023)
Taxifolin (TA) is a natural flavonoid found in many foods and medicinal plants with well-documented antioxidant and anti-inflammatory properties. Cyclophosphamide (CP) is an effective antineoplastic and immunosuppressive agent; however, it is associa
Externí odkaz:
https://doaj.org/article/ceb1d9ddb95f4901ad7b9172dd3b54fc
Publikováno v:
Annals of Agricultural Sciences, Vol 66, Iss 1, Pp 63-74 (2021)
Heavy metals (HMs) pollution is becoming influential severe trouble in the farming ecosystem, where it causes serious health problems for many living organisms. This study was conducted to estimate the HMs accumulation under different sites from agri
Externí odkaz:
https://doaj.org/article/3232024e88234854a22482a84373f869
Autor:
Osama Y. Althunibat, Mohammad H. Abukhalil, Saleem H. Aladaileh, Haitham Qaralleh, Wesam Al-Amarat, Manal A. Alfwuaires, Abdulmohsen I. Algefare, Nader Ibrahim Namazi, Sahar J. Melebary, Ahmad O. Babalghith, Carlos Adam Conte-Junior
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Gentamicin (GEN) is a bactericidal aminoglycoside known to cause nephrotoxicity. Formononetin (FN) is a potent flavonoid that exhibits numerous promising pharmacological activities. In this study, we have assessed the nephroprotective efficacy of FN
Externí odkaz:
https://doaj.org/article/86d853b2414d43f8bd29caf22fabc5b4
Autor:
Manal A. Alfwuaires, Abdulmohsen I. Algefare, Eman Afkar, Sherine Abdel Salam, Heba Ibrahim Abd El-Moaty, Gehan M. Badr
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112148- (2021)
Ulcerative colitis (UC) is a gastrointestinal inflammatory disease with a multifactorial pathophysiology. This study aims to investigate the immunomodulatory effect of Portulaca oleracea leaf ethanolic extract (POE) on acetic acid (AA)-induced UC in
Externí odkaz:
https://doaj.org/article/9a208e0c15fd47feb48337f7396ebd98
Autor:
Heba M. Obeidat, Osama Y. Althunibat, Manal A. Alfwuaires, Saleem H. Aladaileh, Abdulmohsen I. Algefare, Afaf F. Almuqati, Fawaz Alasmari, Hammad Khalifeh Aldal’in, Abdulkareem A. Alanezi, Bader Alsuwayt, Mohammad H. Abukhalil
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1546 (2022)
Oxidative stress and inflammation are key components in cardiovascular diseases and heart dysfunction. Herein, we evaluated the protective effects of (+)-taxifolin (TAX), a potent flavonoid with significant antioxidant and anti-inflammatory actions,
Externí odkaz:
https://doaj.org/article/47aad2e8ea9c434b8308db54e7a285db
Autor:
Mohammad H. Abukhalil, Osama Y. Althunibat, Saleem H. Aladaileh, Wesam Al-Amarat, Heba M. Obeidat, Alayn' Al-marddyah A. Al-khawalde, Omnia E. Hussein, Manal A. Alfwuaires, Abdulmohsen I. Algefare, Khalid M. Alanazi, Farhan K. Al-Swailmi, Hany H. Arab, Ayman M. Mahmoud
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss , Pp 111410- (2021)
Cardiovascular complications are the leading cause of morbidity in diabetes. Oxidative stress and inflammation are implicated in the development and progression of diabetic cardiomyopathy (DCM). This study explored the cardioprotective effect of gala
Externí odkaz:
https://doaj.org/article/14a233231815493bae66473735d2d5d1
Autor:
Wesam Al-Amarat, Mohammad H. Abukhalil, Reem S. Alruhaimi, Haifa A. Alqhtani, Nouf Aldawood, Manal A. Alfwuaires, Osama Y. Althunibat, Saleem H. Aladaileh, Abdulmohsen I. Algefare, Abdulkareem A. Alanezi, Ali M. AbouEl-ezz, Ahmad F. Ahmeda, Ayman M. Mahmoud
Publikováno v:
Metabolites, Vol 12, Iss 7, p 648 (2022)
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide (CP). This study investigated the protective role of the flavone apigenin (API) against CP-induced liver damage, pointing to the involvement of Nrf2/HO-1 signali
Externí odkaz:
https://doaj.org/article/dd79cb89e44b450bb4be5cb94a4a9417
Autor:
Abdulmohsen I. Algefare
Publikováno v:
Life, Vol 12, Iss 8, p 1150 (2022)
Cadmium (Cd) is an inessential trace metal that accumulates in the kidney and may lead to renal toxicity by mediating oxidative stress (OS), inflammatory reactions, and apoptosis. The main objective of this experiment was to inspect the protecting po
Externí odkaz:
https://doaj.org/article/3ef6c88c59244e0a922e2e84cb19819b
Publikováno v:
Drug and Chemical Toxicology. :1-9