Výsledky vyhledávání - "Abdulmelik Aytatli"

Akademický článek

CURRENT CANCER STEM CELL BIOMARKERS IN TONGUE SQUAMOUS CELL CARCINOMA

Autor: Omer Faruk Karatas, Seyma Teber, Ahmet Yilmaz, Asli Baltacioglu, Selinay Merve Kilic, Emel Poyraz, Abdulmelik Aytatli, Sumeyye Ozturk, Ayse Varol

Publikováno v: Trakya University Journal of Natural Sciences, Vol 19, Iss 2, Pp 197-207 (2018)

Tongue squamous cell carcinoma (TSCC) is known to be the most malignant cancer type amongst other oral cancers with increasing incidence and mortality rates in the past five years. Since the life expectancy for TSCC patients is limited and the curren

Externí odkaz: https://doaj.org/article/158153db83b84f86a0fb98ccbfd7e2ed

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Design, Synthesis, and Biological Evaluation of Indole-Modified Tamoxifen Relatives as Potent Anticancer Agents

Autor: Berrak Ertugrul, Abdulmelik Aytatli, ömer faruk Karatas, Nurullah Saracoglu

Publikováno v: RSC Medicinal Chemistry.

Modulation of existing drugs is an attractive strategy to achieve improved activity in cancer therapy by lowering their effective dose. Preparation of relatives has been suggested and explored to improve...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::401ab514c1a22ba84cacc472033692d4
https://doi.org/10.1039/d3md00157a

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AZD4547 targets the FGFR/Akt/SOX2 axis to overcome paclitaxel resistance in head and neck cancer

Autor: Michael Ittmann, Neslisah Barlak, Betul Gundogdu, Omer Faruk Karatas, Abdulmelik Aytatli, Hasan Onur Caglar, Arzu Tatar, Fatma Sanli

Publikováno v: Cellular Oncology. 45:41-56

Development of chemoresistance is one of the major obstacles to the treatment of head and neck squamous cell carcinoma (HNSCC). The PI3K/Akt pathway, involved in drug resistance, has been found to be overactivated in > 90% of HNSCCs. Aberrant activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60dce560fb2481d759d24baced347085
https://doi.org/10.1007/s13402-021-00645-6

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MicroRNA‐145 transcriptionally regulates Semaphorin 3A expression in prostate cancer cells

Autor: Elanur Aydin Karatas, Omer Faruk Karatas, Fatma Sanli, Serkan Ortucu, Abdulmelik Aytatli, Neslisah Barlak, Ozel Capik, Ahsen Kilic, Aysenur Yazici

Publikováno v: Cell Biology International. 45:1082-1090

Prostate cancer (PCa) is one of the most prevalent cancer types among males. Differential expression of microRNAs is associated with various cancers including PCa. Although mature microRNAs are preferentially located in the cytoplasm, several studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2855447645390592a78e1937d3cdfdb8
https://doi.org/10.1002/cbin.11554

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The AKT antagonist AZD5363 suppresses features associated with cancer progression in human larynx cancer cells

Autor: Ahsen Kilinç, Fatma Sanli, Neslisah Barlak, Ozel Capik, Omer Faruk Karatas, Abdulmelik Aytatli

Publikováno v: Volume: 6, Issue: 5 380-387
The European Research Journal

Objectives: Larynx cancer (LCa) represents approximately 30% of all cancers seen in the head and neck region, with an unchanged overall survival rate over the last decades. Although several novel diagnostic and therapeutic options has been developed,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ceca089813409ae3d65dd435ec3b936
https://doi.org/10.18621/eurj.624088

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Mode of action of carboplatin via activating p53/miR‐145 axis in head and neck cancers

Autor: Neslisah Barlak, Omer Faruk Karatas, Ozel Capik, Abdulmelik Aytatli, Fatma Sanli, Ahsen Kilic

Publikováno v: The Laryngoscope. 130:2818-2824

Objectives In this study, we aimed at investigating the expressions of miR-145 and its well-characterized direct targets on carboplatin treatment. Study design Laboratory study. Methods The effect of carboplatin and miR-145 on the proliferative capac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f61027f6d5aae45c6696a51386962be
https://doi.org/10.1002/lary.28492

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ING5 inhibits cancer aggressiveness by inhibiting Akt and activating p53 in prostate cancer

Autor: Michael Ittmann, Serkan Ortucu, Omer Faruk Karatas, Neslisah Barlak, Ozel Capik, Fatma Sanli, Abdulmelik Aytatli, Aysenur Yazici, Ahsen Kilic

Publikováno v: Cell biology international.

Prostate cancer (PCa) is one of the most common types of cancer in men. In several recent studies, chromosomal deletions in the q arm of chromosome 2, where ING5 resides within, have been identified in various cancer types including PCa. In this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e18986fe4ba98342fd24571c272fa97
https://pubmed.ncbi.nlm.nih.gov/31475765

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CURRENT CANCER STEM CELL BIOMARKERS IN TONGUE SQUAMOUS CELL CARCINOMA

Autor: Selinay Merve Kilic, Abdulmelik Aytatli, Ahmet Yilmaz, Ayse Varol, Asli Baltacioglu, Seyma Teber, Emel Poyraz, Sumeyye Ozturk, Omer Faruk Karatas

Publikováno v: Volume: 19, Issue: 2 197-207
Trakya University Journal of Natural Sciences
Trakya University Journal of Natural Sciences, Vol 19, Iss 2, Pp 197-207 (2018)

Dilskuamöz hücreli karsinomu (DSHK) son 5 yılda artan insidans ve mortaliteoranları ile birlikte diğer ağız içi kanserleri arasında en kötü huylu kansertipi olarak bilinmektedir. DSHK hastalarının yaşam süreleri sınırlı olduğundanv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0e23d600bfbc935bf4bf5d296bc0d
https://dergipark.org.tr/tr/pub/trkjnat/issue/39729/368829