Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Abdullahi Y. Abbas"'
Autor:
Bashar Farida, Kasimu G. Ibrahim, Bilyaminu Abubakar, Ibrahim Malami, Muhammad B. Bello, Murtala B. Abubakar, Abdullahi Y. Abbas, Mustapha U. Imam
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 78:127203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a850d2b8e861a8301574613c3f4a884b
https://doi.org/10.1016/j.jtemb.2023.127203
https://doi.org/10.1016/j.jtemb.2023.127203
Autor:
Chris Pepper, Frankie Lam, Hao Shao, David W. Foley, Peter Fischer, Tracey D. Bradshaw, Abdullahi Y. Abbas, Shiliang Huang, Shudong Wang, Pavel Gershkovich
Cyclin-dependent kinases (CDKs) are a family of Ser/Thr kinases involved in cell cycle and transcriptional regulation. CDK9 regulates transcriptional elongation and this unique property has made it a potential target for several diseases. Due to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa0033351dd727bdb5075ba87dd64aa
Autor:
Osama Chahrour, Xiangrui Liu, Ben Noll, Theodosia Teo, Aik Wye Goh, Mingfeng Yu, Abdullahi Y. Abbas, Robert W. Milne, Longjin Zhong, Christopher J. Sumby, Shiliang Huang, Anran Hu, Frankie Lam, Julian Adams, Peng Li, Carol Midgley, Sarah Diab, Tiangong Lu, Shudong Wang
Publikováno v:
Journal of Medicinal Chemistry. 57:2275-2291
ON01910.Na is a highly effective anticancer agent that induces mitotic arrest and apoptosis. Clinical studies with ON01910 in cancer patients have shown efficacy along with an impressive safety profile. While ON01910 is highly active against cancer c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5e0814bf8d1fa96a2ff62967c383c4
https://doi.org/10.1021/jm4019614
https://doi.org/10.1021/jm4019614
Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1317-1321
We herein report the synthesis, biological activity and structure–activity relationship of derivatives of 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole and benzo[d]imidazole. A lead compound 6o demonstrates potent anti-proliferative activity and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672b836ed39cd20b047e4c2745e313ac
https://doi.org/10.1016/j.bmcl.2011.12.088
https://doi.org/10.1016/j.bmcl.2011.12.088
Autor:
Chris Pepper, Peng Li, Shudong Wang, Tracey D. Bradshaw, Frankie Lam, Hao Shao, Abdullahi Y. Abbas, Theodosia Teo, Yi Chen, Elisabeth Jane Walsby, Peter Fischer, Jian Ding, Julian Adams
Publikováno v:
Oncotarget
ResearcherID
Scopus-Elsevier
ResearcherID
Scopus-Elsevier
Dysregulation of cellular transcription and translation is a fundamental hallmark\ud of cancer. As CDK9 and Mnks play pivotal roles in the regulation of RNA transcription\ud and protein synthesis, respectively, they are important targets for drug dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4841629d0f0c0247327d2408b149c5
https://pubmed.ncbi.nlm.nih.gov/25277198
https://pubmed.ncbi.nlm.nih.gov/25277198
Autor:
Jane A. Endicott, Chris Pepper, Alison J. Hole, Abdullahi Y. Abbas, Shenhua Shi, Frankie Lam, Shudong Wang, Martin E.M. Noble, Sonja Baumli, Hao Shao, Xiangrui Liu, David W. Foley, Shiliang Huang, Peter Fischer
Publikováno v:
Journal of Medicinal Chemistry
Cancer cells often have a high demand for antiapoptotic proteins in order to resist programmed cell death. CDK9 inhibition selectively targets survival proteins and reinstates apoptosis in cancer cells. We designed a series of 4-thiazol-2- anilinopyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ca38616b46173ee2f7407ba2de20a5
https://pubmed.ncbi.nlm.nih.gov/23301767
https://pubmed.ncbi.nlm.nih.gov/23301767
Autor:
Abdullahi Y. Abbas, Ahmad Sanusi Zakariya'u, Khalifa Muhammad Aljameel, Mu'awiya Jibir, Abubakar Mukhtar Danmusa, Nasiru Muhammad
Publikováno v:
International Journal of Livestock Research. 6:69
A study was undertaken to investigate and compare the major ethnic groups (Hausa, Igbo and Yoruba) of Nigeria and their corresponding Sex classes (male and female) for perceived preference of salt in meat. Forty individuals from each ethnic group con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d8fb87d6fcf450baf023e77db2c16ec
https://doi.org/10.5455/ijlr.20160609015026
https://doi.org/10.5455/ijlr.20160609015026
Autor:
Shenhua Shi, Shudong Wang, David W. Foley, Martin E.M. Noble, Shiliang Huang, Tracey D. Bradshaw, Abdullahi Y. Abbas, Sonja Baumli, Jane A. Endicott, Alison J. Hole, Peter Fischer, Hao Shao, Chris Pepper
Publikováno v:
Cancer Research. 73:697-697
Cyclin-dependent kinases (CDKs) are a family of Ser/Thr kinases involved in cell cycle and transcriptional regulation. Most of the CDK inhibitors reported to date have multiple targets and it is unclear whether specific inhibition of one of the CDKs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06c478a1ce446f73bff531283369f0cb
https://doi.org/10.1158/1538-7445.am2013-697
https://doi.org/10.1158/1538-7445.am2013-697
Autor:
Chris Pepper, T.D. Bradshaw, Hao Shao, Peter Fischer, Shiliang Huang, Shudong Wang, Jane A. Endicott, Shenhua Shi, David W. Foley, Abdullahi Y. Abbas
Publikováno v:
European Journal of Cancer. 48:84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a108b3f187dc20ce08b1e76c775c31e
https://doi.org/10.1016/s0959-8049(12)72072-5
https://doi.org/10.1016/s0959-8049(12)72072-5