Comparative pre- and post-treatment effects of Nigella sativa oil on lipid profile and antioxidant enzymes in a rat model of diabetes mellitus

Autor: Abdulwasiu A. Busari, Abdullahi A. Adejare, Sidikat O. Kelani, Khalid O. Imam, Abdulhakeem A. Awesu, Idayat Adefila-Sanni

Publikováno v: Nigerian Journal of Medicine, Vol 29, Iss 3, Pp 415-421 (2020)

Background: Lipid profile dysregulation and oxidative stress are important risk factors for cardiovascular disease in diabetic individuals. Nigella Sativa (NS) oil has been reported to have a favorable effect on triglycerides (TG) in rat models of di

Externí odkaz: https://doaj.org/article/bc146ff686ef44599d9d7f2977fc4551

Antihypertensive Effect of Kolaviron, a Bioflavonoid From Garcinia kola, in L-NAME Induced Hypertension in Rats

Autor: Francis J. Olatoye, Abidemi James Akindele, Okikioluwa E. Balogun, Olufunsho Awodele, Abdullahi A. Adejare

Publikováno v: Natural Product Communications. 18:1934578X2211486

The antihypertensive effect of Kolaviron (KV) has been demonstrated in ethanol- and sucrose-model of hypertension in our previous studies. However, there remains a need to further confirm and validate this effect in other models of hypertension. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fce1d275a2e2d31592c11d440e5cb762
https://doi.org/10.1177/1934578x221148608

L-arginine supplementation reduces blood pressure and plasma lipid levels in an animal model of perimenopause induced by 4-Vinylcyclohexene diepoxide

Autor: O.A. Akinnibosun, Adedunni Olusanya, I.C. Udenze, A P Arikawe, II Olatunji-Bello, Odunayo Moyosore Olumide, Abdullahi A. Adejare, Janete Aparecida Anselmo-Franci

Publikováno v: Bulletin of Egyptian Society for Physiological Sciences. 39:118-128

The incidence of women developing high blood pressure during perimenopause has been documented and is sustained till menopause. However, no study till date on beneficial effects of L-arginine supplementation on BP during perimenopause in humans and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc5bf863e41379e88be6788dadca39d4
https://doi.org/10.21608/besps.2019.6288.1008

Protective but Non-Synergistic Effects of Nigella Sativa and Vitamin E against Cisplatin-Induced Renal Toxicity and Oxidative Stress in Wistar Rats

Autor: Abdullahi A. Adejare, Oludaisi A. Oduniyi, Ibrahim A. Oreagba, Abdulwasiu Adeniyi Busari, Khadijah B. Ismail-Badmus, Abiodun F. Shodipe

Publikováno v: Drug research. 68(12)

Background Cisplatin is an anti-cancer drug that causes nephrotoxicity and oxidative stress. Extracts of Nigella sativa is nephroprotective. Vitamin E is also a potent antioxidant. This study sought to determine a possible synergistic effect of admin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2501b1fe04cd1ad7a3cdf5ff1a6f6d7
https://pubmed.ncbi.nlm.nih.gov/29945276

Renal denervation ameliorated salt-induced hypertension by improving cardiac work, cardiac enzyme and oxidative balance in Sprague-Dawley rats.

Autor: Adejare A; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria., Oloyo A; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria., Dahud Y; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria., Adeshina M; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria., Agbaje A; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria., Ejim C; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria., Ismail-Badmus K; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria., Jaja S; Cardiovascular-Renal Unit, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Lagos, Nigeria.

Publikováno v: International journal of cardiology. Cardiovascular risk and prevention [Int J Cardiol Cardiovasc Risk Prev] 2024 May 24; Vol. 21, pp. 200290. Date of Electronic Publication: 2024 May 24 (Print Publication: 2024).