Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Abdullah Saleh Al‑Wajeeh"'
Autor:
Futoon Abedrabbu Al-Rawashde, Ola M. Al-Sanabra, Moath Alqaraleh, Ahmad Q. Jaradat, Abdullah Saleh Al-Wajeeh, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 884 (2023)
The epigenetic silencing of tumor suppressor genes (TSGs) is critical in the development of chronic myeloid leukemia (CML). SHP-1 functions as a TSG and negatively regulates JAK/STAT signaling. Enhancement of SHP-1 expression by demethylation provide
Externí odkaz:
https://doaj.org/article/19355200a5a648b6bfe903e67a051535
Autor:
Hanan Kamel M. Saad, Wan Rohani Wan Taib, Azly Sumanty Ab Ghani, Imilia Ismail, Futoon Abedrabbu Al-Rawashde, Belal Almajali, Maysa Alhawamdeh, Alawiyah Awang Abd Rahman, Abdullah Saleh Al-wajeeh, Hamid Ali Nagi Al-Jamal
Publikováno v:
Diagnostics, Vol 13, Iss 7, p 1247 (2023)
Background: β-thalassaemia is a disorder caused by mutations in the β-globin gene, leading to defective production of haemoglobins (Hb) and red blood cells (RBCs). It is characterised by anaemia, ineffective erythropoiesis, and iron overload. Patie
Externí odkaz:
https://doaj.org/article/02a0af964a2a4d96b6915aaf84db6309
Autor:
Futoon Abedrabbu Al-Rawashde, Abdullah Saleh Al-wajeeh, Mansoureh Nazari Vishkaei, Hanan Kamel M. Saad, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1123 (2022)
Constitutive activation of Janus tyrosine kinase-signal transducer and activator of transcription (JAK/STAT) and Phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathways plays a crucial role in the developmen
Externí odkaz:
https://doaj.org/article/48cc5f21df914819bd5b47063ddc4801
Autor:
Belal Almajali, Muhammad Farid Johan, Abdullah Saleh Al-Wajeeh, Wan Rohani Wan Taib, Imilia Ismail, Maysa Alhawamdeh, Nafe M. Al-Tawarah, Wisam Nabeel Ibrahim, Futoon Abedrabbu Al-Rawashde, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 307 (2022)
Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance, making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is impossible, and c-Myc upstream regulator pathways could be targeted inst
Externí odkaz:
https://doaj.org/article/6a4b4bdee89045569bac4d5d106e3a66
Autor:
Ayman A. Swelum, Manal E. Shafi, Najah M. Albaqami, Mohamed T. El-Saadony, Ahmed Elsify, Mohamed Abdo, Ayman E. Taha, Abdel-Moneim E. Abdel-Moneim, Naif A. Al-Gabri, Amer A. Almaiman, Abdullah Saleh Al-wajeeh, Vincenzo Tufarelli, Vito N. Staffa, Mohamed E. Abd El-Hack
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
The medical authority in China, especially in Wuhan city, reported on December 2019 a large number of highly fatal, rapidly spreading viral pneumonia caused by an unknown coronavirus. The common history of all the patients was their visiting a Wuhan'
Externí odkaz:
https://doaj.org/article/b1346aef489343479103d21e6a0c1956
Autor:
Abdullah Saleh Al-Wajeeh, Salizawati Muhamad Salhimi, Majed Ahmed Al-Mansoub, Imran Abdul Khalid, Thomas Michael Harvey, Aishah Latiff, Mohd Nazri Ismail
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227404 (2020)
BACKGROUND:Breast cancer is the fifth most prevalent cause of death among women worldwide. It is also one of the most common types of cancer among Malaysian women. This study aimed to characterize and differentiate the proteomics profiles of differen
Externí odkaz:
https://doaj.org/article/2f7e8b3ffd784291b659a4adb2371b68
Autor:
Hanan Kamel M. Saad, Alawiyah Awang Abd Rahman, Azly Sumanty Ab Ghani, Wan Rohani Wan Taib, Imilia Ismail, Muhammad Farid Johan, Abdullah Saleh Al-Wajeeh, Hamid Ali Nagi Al-Jamal
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 189 (2022)
Iron homeostasis is regulated by hepcidin, a hepatic hormone that controls dietary iron absorption and plasma iron concentration. Hepcidin binds to the only known iron export protein, ferroportin (FPN), which regulates its expression. The major facto
Externí odkaz:
https://doaj.org/article/acd8c0c169264173ab759391aa6a460b
Autor:
Futoon Abedrabbu Al-Rawashde, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Syed Ahmad Tajudin Tuan Johari, Belal Almajali, Abdullah Saleh Al-wajeeh, Mansoureh Nazari Vishkaei, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1287 (2021)
Epigenetic silencing of tumor suppressor genes (TSGs) plays an essential role in cancer pathogenesis, including acute myeloid leukemia (AML). All of SHP-1, SOCS-1, and SOCS-3 are TSGs that negatively regulate JAK/STAT signaling. Enhanced re-expressio
Externí odkaz:
https://doaj.org/article/052f0ad5009f4de5b866811ac4138394
Autor:
Al-Jamal, Futoon Abedrabbu Al-Rawashde, Ola M. Al-Sanabra, Moath Alqaraleh, Ahmad Q. Jaradat, Abdullah Saleh Al-Wajeeh, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Hamid Ali Nagi
Publikováno v:
Pharmaceuticals; Volume 16; Issue 6; Pages: 884
The epigenetic silencing of tumor suppressor genes (TSGs) is critical in the development of chronic myeloid leukemia (CML). SHP-1 functions as a TSG and negatively regulates JAK/STAT signaling. Enhancement of SHP-1 expression by demethylation provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::88fd02f7d5ca5c01755ded5139c0ab0d
Autor:
Imilia Ismail, Hanan Kamel M. Saad, Abdullah Saleh Al‑Wajeeh, Muhammad Farid Johan, Wan Rohani Wan Taib, Hamid Ali Nagi Al‑Jamal
Publikováno v:
Experimental and Therapeutic Medicine
Iron homeostasis is regulated by hepcidin (HEPC) that controls the dietary iron absorption and iron recycling. HEPC deficiency contributes to iron overload in β-thalassemia patients. The present study aimed to investigate the correlation between HEP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a367127916d78be1cc6c0a677e0f46d
https://doi.org/10.3892/etm.2021.10838
https://doi.org/10.3892/etm.2021.10838