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pro vyhledávání: '"Abdullah R. Ahmed"'
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611258
The need to describe and understand signaling pathways in live cell is seen as a primary route to identifying and developing targeted medicines. Signaling cascade is also seen as a complex communication and involves interactions between multiple inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4768ad5f14ad728cadfef285025dc4b
https://doi.org/10.1007/978-1-0716-1126-5_16
https://doi.org/10.1007/978-1-0716-1126-5_16
Autor:
Stanley W. Botchway, Abdullah R. Ahmed, Rahul B. Yadav, Richard B. Hitchman, Chris Hawes, Maud Dumoux, Christopher D. Stubbs, Anthony W. Parker, Raymond J. Owens
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Knowledge of protein signalling pathways in the working cell is seen as a primary route to identifying and developing targeted medicines. In recent years there has been a growing awareness of the importance of the mTOR pathway, making it an attractiv
Autor:
Stanley W. Botchway, Alessia Candeo, Rahul B. Yadav, Sofia D'Abrantes, Sarah R. Needham, Abdullah R. Ahmed, Anthony W. Parker
Publikováno v:
Journal of Photochemistry and Photobiology. B, Biology
The range of cellular functions the mechanistic target of rapamycin (mTOR) protein performs makes it an attractive drug target for cancer therapy. However, the cellular localisation and mode of action of second generation inhibitors of mTOR is poorly