Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Abdullah Mahmood, Ali"'
Autor:
Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Lyndsey Bolanos, Mark Wunderlich, Johann-Christoph Jann, Alina Wein, Eva Altrock, Marie Demmerle, Sanjay Mukherjee, Abdullah Mahmood Ali, Felicitas Rapp, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ahmed Jawhar, Ali Darwich, Patrick Wuchter, Christel Weiss, Azra Raza, Jason M. Foulks, Daniel T. Starczynowski, Feng-Chun Yang, Georgia Metzgeroth, Laurenz Steiner, Mohamad Jawhar, Wolf-Karsten Hofmann, Daniel Nowak
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Inhibitors of anti-apoptotic BCL-2 family proteins in combination with chemotherapy and hypomethylating agents (HMA) are promising therapeutic approaches in acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS). Alvocidib, a cycl
Externí odkaz:
https://doaj.org/article/587fe7bf73e84c44b2b804ab4433a656
Autor:
Abdullah Mahmood Ali, Yumin Huang, Ronald Feitosa Pinheiro, Fumin Xue, Jingping Hu, Nicholas Iverson, Daniela Hoehn, Diego Coutinho, Jehanzeb Kayani, Brian Chernak, Joseph Lane, Christopher Hillyer, Naomi Galili, Joseph Jurcic, Narla Mohandas, Xiuli An, Azra Raza
Publikováno v:
Blood Advances, Vol 2, Iss 12, Pp 1393-1402 (2018)
Abstract: Anemia is the defining feature in most patients with myelodysplastic syndromes (MDS), yet defects in erythropoiesis have not been well characterized. We examined freshly obtained bone marrow (BM) samples for stage-specific abnormalities dur
Externí odkaz:
https://doaj.org/article/53545c28418145669201fd7942148022
Autor:
Stavroula Kousteni, Azra Raza, Martin Carroll, Raul Rabadán, Siddhartha Mukherjee, Matthias Quick, Bryan L. Roth, Irwin Kurland, Rossella Labella, Brygida Bisikirska, Xi-Ping Huang, Yongfeng Liu, Na Luo, Xiaochuan Shan, Eva Gil-Iturbe, Junfei Zhao, Abdullah Mahmood Ali, Florence Borot, Marta Galán-Díez
Supplementary Table from Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5f455c4b987d9244c410ef78b9dbe8
https://doi.org/10.1158/2159-8290.22541011.v1
https://doi.org/10.1158/2159-8290.22541011.v1
Autor:
Stavroula Kousteni, Azra Raza, Martin Carroll, Raul Rabadán, Siddhartha Mukherjee, Matthias Quick, Bryan L. Roth, Irwin Kurland, Rossella Labella, Brygida Bisikirska, Xi-Ping Huang, Yongfeng Liu, Na Luo, Xiaochuan Shan, Eva Gil-Iturbe, Junfei Zhao, Abdullah Mahmood Ali, Florence Borot, Marta Galán-Díez
Supplementary Data from Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142943b2473ac9be7b099c430256a8fe
https://doi.org/10.1158/2159-8290.22541038
https://doi.org/10.1158/2159-8290.22541038
Autor:
Stavroula Kousteni, Azra Raza, Martin Carroll, Raul Rabadán, Siddhartha Mukherjee, Matthias Quick, Bryan L. Roth, Irwin Kurland, Rossella Labella, Brygida Bisikirska, Xi-Ping Huang, Yongfeng Liu, Na Luo, Xiaochuan Shan, Eva Gil-Iturbe, Junfei Zhao, Abdullah Mahmood Ali, Florence Borot, Marta Galán-Díez
Remodeling of the microenvironment by tumor cells can activate pathways that favor cancer growth. Molecular delineation and targeting of such malignant-cell nonautonomous pathways may help overcome resistance to targeted therapies. Herein we leverage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c10341b7b14e1e726748d36c484aa99
https://doi.org/10.1158/2159-8290.c.6549538
https://doi.org/10.1158/2159-8290.c.6549538
Autor:
Amom Ruhikanta Meetei, Michael M. Seidman, Kebola Wahengbam, Arun Pradhan, Manikandan Paramasivam, Abdullah Mahmood Ali, Thiyam Ramsing Singh
Fanconi anemia (FA) is a genome instability syndrome that has been associated with both cancer predisposition and bone marrow failure. FA proteins are involved in cellular response to replication stress in which they coordinate DNA repair with DNA re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e4184fae5977477d041c5a7b84ac3f
https://doi.org/10.1158/0008-5472.c.6504926.v1
https://doi.org/10.1158/0008-5472.c.6504926.v1
Autor:
Amom Ruhikanta Meetei, Michael M. Seidman, Kebola Wahengbam, Arun Pradhan, Manikandan Paramasivam, Abdullah Mahmood Ali, Thiyam Ramsing Singh
PDF file - 98K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a1ccd220c7484cb50505b640ac59b1
https://doi.org/10.1158/0008-5472.22397852.v1
https://doi.org/10.1158/0008-5472.22397852.v1
Autor:
Amom Ruhikanta Meetei, Michael M. Seidman, Kebola Wahengbam, Arun Pradhan, Manikandan Paramasivam, Abdullah Mahmood Ali, Thiyam Ramsing Singh
PDF file - 407K, DNA-damage-induced phosphorylation of FANCM is ATR dependent (S1); Peptides released from FANCM protein were analyzed for putative phosphorylation sites by mass spectrometry (S2); Immunoblot showing that antibody raised against phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf64ceaeba909bfeec8f719f2265517
https://doi.org/10.1158/0008-5472.22397849
https://doi.org/10.1158/0008-5472.22397849
Autor:
Florence Borot, Olivier Humbert, Gregory A Newby, Emily Fields, Sajeev Kohli, Stefan Radtke, George S. Laszlo, Thiyagaraj Mayuranathan, Abdullah Mahmood Ali, Mitchell J. Weiss, Jonathan S. Yen, Roland B. Walter, David R. Liu, Siddhartha Mukherjee, Hans-Peter Kiem
Publikováno v:
bioRxiv
On-target toxicity to normal cells is a major safety concern with targeted immune and gene therapies. Here, we developed a base editing (BE) approach exploiting a naturally occurring CD33 single nucleotide polymorphism leading to removal of full-leng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efe9077b262227a9035dab3e8b8664f
https://europepmc.org/articles/PMC9980058/
https://europepmc.org/articles/PMC9980058/
Autor:
Alan Burke, Florence Borot, Xing Du, Michael Churchill, Jian Ding, Albert Mridul Grass, Philip DeSouza, Abdullah Mahmood Ali, Siddhartha Mukherjee
Many therapeutic bispecific T-cell engagers (BiTEs) are in clinical trials. A modular and efficient process to create BiTEs would accelerate their development and clinical applicability. In this study, we present the design, production, and functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c23df4173f5db9b30eb428ab8e0227
https://doi.org/10.21203/rs.3.rs-2135768/v1
https://doi.org/10.21203/rs.3.rs-2135768/v1