Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Abdullah, UB"'
Publikováno v:
EMBO Journal
EMBO Journal, 2017, 36, pp.2047-2060. ⟨10.15252/embj.201796664⟩
EMBO Journal, 2017, 36, pp.2047-2060. ⟨10.15252/embj.201796664⟩
During replication-coupled DNA interstrand crosslink (ICL) repair, the XPF-ERCC1 endonuclease is required for the incisions that release, or "unhook", ICLs, but the mechanism of ICL unhooking remains largely unknown. Incisions are triggered when the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7c042c1cb60831145d7c1604be808321
https://ora.ox.ac.uk/objects/uuid:65133b95-7b96-4fe0-9b26-5e000080fb19
https://ora.ox.ac.uk/objects/uuid:65133b95-7b96-4fe0-9b26-5e000080fb19
Autor:
Bernkopf M; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK.; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria., Abdullah UB; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Bush SJ; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wood KA; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Ghaffari S; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Giannoulatou E; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia., Koelling N; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Maher GJ; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Thibaut LM; Centre for Population Genomics, Garvan Institute of Medical Research, UNSW Sydney, Sydney, NSW, Australia., Williams J; Oxford Genetics Laboratories, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Blair EM; NIHR Oxford Biomedical Research Centre, Oxford, UK.; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Kelly FB; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Bloss A; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Burkitt-Wright E; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.; Division of Evolution and Genomic Sciences, University of Manchester, Manchester, UK., Canham N; Department of Clinical Genetics, Liverpool Women's NHS Foundation Trust, Liverpool, UK., Deng AT; Clinical Genetics Department, Guy's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, UK., Dixit A; Nottingham Regional Genetics Service, City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK., Eason J; Nottingham Regional Genetics Service, City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK., Elmslie F; South West Thames Regional Genetics Service, St George's University Hospitals NHS Foundation Trust, London, UK., Gardham A; North West Thames Regional Genetics Service, London North West University Healthcare NHS Trust, Northwick Park Hospital, Harrow, UK., Hay E; North East Thames Regional Genetics Service, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Holder M; Clinical Genetics Department, Guy's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, UK., Homfray T; South West Thames Regional Genetics Service, St George's University Hospitals NHS Foundation Trust, London, UK., Hurst JA; North East Thames Regional Genetics Service, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Johnson D; Sheffield Clinical Genetics Service, Sheffield Children's NHS Foundation Trust, Sheffield, UK., Jones WD; North East Thames Regional Genetics Service, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Kini U; NIHR Oxford Biomedical Research Centre, Oxford, UK.; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Kivuva E; Clinical Genetics, Royal Devon & Exeter Hospital (Heavitree), Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Kumar A; North East Thames Regional Genetics Service, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Lees MM; North East Thames Regional Genetics Service, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Leitch HG; Nottingham Regional Genetics Service, City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK.; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Morton JEV; West Midlands Regional Clinical Genetics Service and Birmingham Health Partners, Birmingham Women's and Children's Hospitals NHS Foundation Trust, Birmingham, UK., Németh AH; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Ramachandrappa S; Clinical Genetics Department, Guy's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, UK., Saunders K; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Shears DJ; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Side L; Wessex Clinical Genetics Service, University Hospital Southampton, Princess Anne Hospital, Southampton, UK., Splitt M; Northern Genetics Service, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK., Stewart A; Sheffield Clinical Genetics Service, Sheffield Children's NHS Foundation Trust, Sheffield, UK., Stewart H; Oxford Centre for Genomic Medicine, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Suri M; Nottingham Regional Genetics Service, City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK., Clouston P; Oxford Genetics Laboratories, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Davies RW; Department of Statistics, University of Oxford, Oxford, UK., Wilkie AOM; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Goriely A; Clinical Genetics Group, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. anne.goriely@imm.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. anne.goriely@imm.ox.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 Feb 15; Vol. 14 (1), pp. 853. Date of Electronic Publication: 2023 Feb 15.
Autor:
Varshney D; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK., Cuesta SM; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; Data Sciences and Quantitative Biology, Discovery Sciences, AstraZeneca, Cambridge, UK., Herdy B; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK., Abdullah UB; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.; Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Tannahill D; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK., Balasubramanian S; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. sb10031@cam.ac.uk.; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. sb10031@cam.ac.uk.; School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP, UK. sb10031@cam.ac.uk.
Publikováno v:
Scientific reports [Sci Rep] 2021 Nov 23; Vol. 11 (1), pp. 22735. Date of Electronic Publication: 2021 Nov 23.
Autor:
Amunugama R; Howard Hughes Medical Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Willcox S; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Wu RA; Howard Hughes Medical Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Abdullah UB; Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., El-Sagheer AH; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Brown T; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK., McHugh PJ; Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Griffith JD; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: jdg@med.unc.edu., Walter JC; Howard Hughes Medical Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: johannes_walter@hms.harvard.edu.
Publikováno v:
Cell reports [Cell Rep] 2018 Jun 19; Vol. 23 (12), pp. 3419-3428.
Autor:
Abdullah UB; Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., McGouran JF; Department of Chemistry, University of Oxford, Oxford, UK., Brolih S; Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Ptchelkine D; Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Research Complex at Harwell, Rutherford Appleton Laboratory, Oxford, UK., El-Sagheer AH; Department of Chemistry, University of Oxford, Oxford, UK., Brown T; Department of Chemistry, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK., McHugh PJ; Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK peter.mchugh@imm.ox.ac.uk.
Publikováno v:
The EMBO journal [EMBO J] 2017 Jul 14; Vol. 36 (14), pp. 2047-2060. Date of Electronic Publication: 2017 Jun 12.