Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Abdulla WA"'
Autor:
Abdulla Watad, Alen Zabotti, Yonatan Shneor Patt, Omer Gendelman, Arad Dotan, Niv Ben-Shabat, Lior Fisher, Dennis McGonagle, Howard Amital
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 4, Pp 963-976 (2024)
Abstract Introduction Biologic therapies are licensed for both psoriasis (PsO) and psoriatic arthritis (PsA) with some electronic medical record data suggest that IL (Interleukin)-23 blockers might be more protective in PsA prevention than TNF blocke
Externí odkaz:
https://doaj.org/article/7b8d8878a9ff404f81b9300439010617
Autor:
Abdulla Watad, Dennis G McGonagle, Howard Amital, Tom Macleod, Or Hen, Paula David, Niv Ben-Shabbat
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objective Obesity and age are strongly linked to severe COVID-19 pneumonia where immunomodulatory agents including Janus kinase inhibitors have shown benefits but the efficacy of such therapy in viral pneumonia is not well understood. We evaluated th
Externí odkaz:
https://doaj.org/article/ee103318fd3e4afca66fd64e3d8140f2
Autor:
Yonatan Shneor Patt, Kassem Sharif, Paula David, Or Hen, Omer Gendelman, Yoav Elizur, Basel Ahmaro, Orly Weinstein, Abdulla Watad, Howard Amital, Niv Ben-Shabat
Publikováno v:
Medicina, Vol 60, Iss 11, p 1787 (2024)
Background and Objectives: Sarcoidosis, marked by chronic inflammation and granuloma formation, shows a variable clinical course. While many patients have benign outcomes, others face chronic, life-threatening complications. Mortality studies in sarc
Externí odkaz:
https://doaj.org/article/76864ae77363401b82532be8fe871522
Autor:
Laure Gossec, Josef S Smolen, Alen Zabotti, Georg Schett, Abdulla Watad, Dennis G McGonagle, Annarita Tullio, Salvatore De Vita, Ivan Giovannini, Enzo Errichetti, Ilaria Tinazzi, Luca Quartuccio, Ettore Silvagni, Filippo Fagni, Gabriele De Marco, David Simon, Michael Sticherling
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objective Subjects with subclinical psoriatic arthritis (PsA), defined as the presence of arthralgia in psoriasis (PsO), are at higher risk of PsA but scant real-world data exist. Our aims were to (1) estimate the probability of PsA development in su
Externí odkaz:
https://doaj.org/article/8971c595d6de4d759a3c2abd481be74c
Autor:
Uria Shani, Niv Ben-Shabat, Roula Qassem, Adi Lahat, Mahmud Omar, Einat Savin, Arad Dotan, Yonatan Shneor Patt, Lior Fisher, Galia Zacay, Howard Amital, Abdulla Watad, Kassem Sharif
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: The skin–gut axis, characterized by bidirectional communication between the skin and gut, plays a crucial role in the pathogenesis of psoriasis and inflammatory bowel diseases (IBD). Objectives: We aimed to explore the association betwe
Externí odkaz:
https://doaj.org/article/cd18f0c324224905871e33146b9e575a
Autor:
Kassem Sharif, Mahmud Omar, Adi Lahat, Yonatan Shneor Patt, Howard Amital, Ghanem Zoabi, Nicola Luigi Bragazzi, Abdulla Watad
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Due to its apparent efficacy and safety, dupilumab, a monoclonal antibody that blocks Interleukin 4 (IL-4) and Interleukin 13 (IL-13), has been approved for treating T-helper 2 (Th2) disorders. However, adverse effects like local injectio
Externí odkaz:
https://doaj.org/article/d03e373e545541db8fae7077780f1270
Autor:
Tobias Russell, Hannah Rowe, Charlie Bridgewood, Richard J. Cuthbert, Abdulla Watad, Darren Newton, Elena Jones, Dennis McGonagle
Publikováno v:
Immuno, Vol 1, Iss 4, Pp 545-557 (2021)
Entheseal spinal inflammation and new bone formation with progressive ankylosis may occur in ankylosing spondylitis (AS) and psoriatic arthritis (PsA). This study evaluated whether JAK inhibition with tofacitinib modulated the key disease associated
Externí odkaz:
https://doaj.org/article/6e2ce4d124004ec2a411bdbe09605234
Autor:
Efrosiniia Talalai, Denis Gorobets, Gilad Halpert, Avishai M. Tsur, Harald Heidecke, Yair Levy, Abdulla Watad, Miri Blank, Izhak Michaelevski, Yehuda Shoenfeld, Howard Amital
Publikováno v:
Cells, Vol 12, Iss 11, p 1510 (2023)
The association between the clinical picture of symptomatic women with silicone breast implants (SBI) and dysregulated immunity was in dispute for decades. In the current study, we describe for the first time the functional activity of purified IgG a
Externí odkaz:
https://doaj.org/article/6dbb89bd1a114119861f1fecc72767a1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Humorally associated autoimmune diseases generally show a female predominance whereas ankylosing spondylitis, a disease that overlaps with psoriatic arthritis (PsA), shows a male predominance. The present review ascertains the current knowledge of se
Externí odkaz:
https://doaj.org/article/3200f57d4e4c4c59a905136f10010f66
Autor:
Nicola Luigi Bragazzi, Charlie Bridgewood, Abdulla Watad, Giovanni Damiani, Jude Dzevela Kong, Dennis McGonagle
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundRheumatological and dermatological disorders contribute to a significant portion of the global burden of disease. Big Data are increasingly having a more and more relevant role, being highly ubiquitous and pervasive in contemporary society
Externí odkaz:
https://doaj.org/article/68ad1082c47840f6b1c229f6334ed8e6