Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Abdulkader Azouz"'
Autor:
Kevin Englebert, Anaelle Taquin, Abdulkader Azouz, Valérie Acolty, Sylvie Vande Velde, Marie Vanhollebeke, Hadrien Innes, Louis Boon, Tibor Keler, Oberdan Leo, Stanislas Goriely, Muriel Moser, Guillaume Oldenhove
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113824- (2024)
Summary: Adipose tissue homeostasis relies on the interplay between several regulatory lineages, such as type 2 innate lymphoid cells (ILC2s), T helper 2 (Th2) cells, regulatory T cells, eosinophils, and type 2 macrophages. Among them, ILC2s are nume
Externí odkaz:
https://doaj.org/article/1742e235f1ef4c8ba6548012f51e964e
Autor:
Guillem Sanchez Sanchez, Maria Papadopoulou, Abdulkader Azouz, Yohannes Tafesse, Archita Mishra, Jerry K. Y. Chan, Yiping Fan, Isoline Verdebout, Silvana Porco, Frédérick Libert, Florent Ginhoux, Bart Vandekerckhove, Stanislas Goriely, David Vermijlen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Knowledge about the ontogeny of T cells in the thymus relies heavily on mouse studies because of difficulty to obtain human material. Here the authors perform a single cell analysis of thymocytes from human fetal and paediatric thymic samples to char
Externí odkaz:
https://doaj.org/article/6dfe7ee0d486441f82161526cf2ca7ec
Autor:
Marie Le Moine, Abdulkader Azouz, Guillem Sanchez Sanchez, Solange Dejolier, Muriel Nguyen, Séverine Thomas, Valdrin Shala, Hacene Dreidi, Sébastien Denanglaire, Frédérick Libert, David Vermijlen, Fabienne Andris, Stanislas Goriely
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112876- (2023)
Summary: The co-inhibitory programmed death (PD)-1 signaling pathway plays a major role in the context of tumor-specific T cell responses. Conversely, it also contributes to the maintenance of peripheral tolerance, as patients receiving anti-PD-1 tre
Externí odkaz:
https://doaj.org/article/b082a4b6d11f4acfb5dc137c34148778
Autor:
Natalia Bowakim-Anta, Valérie Acolty, Abdulkader Azouz, Hideo Yagita, Oberdan Leo, Stanislas Goriely, Guillaume Oldenhove, Muriel Moser
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMost T lymphocytes, including regulatory T cells, express the CD27 costimulatory receptor in steady state conditions. There is evidence that CD27 engagement on conventional T lymphocytes favors the development of Th1 and cytotoxic respons
Externí odkaz:
https://doaj.org/article/2ff475beb5f84be899b36ae5412f82bd
Autor:
Elisa Brauns, Abdulkader Azouz, David Grimaldi, Hanxi Xiao, Séverine Thomas, Muriel Nguyen, Véronique Olislagers, Ines Vu Duc, Carmen Orte Cano, Véronique Del Marmol, Pieter Pannus, Frédérick Libert, Sven Saussez, Nicolas Dauby, Jishnu Das, Arnaud Marchant, Stanislas Goriely
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Severe COVID-19 disease is associated with dysregulation of the myeloid compartment during acute infection. Survivors frequently experience long-lasting sequelae, but little is known about the eventual persistence of this immune alteration. Herein, w
Externí odkaz:
https://doaj.org/article/f3362354720b4c629fd0813867086239
Autor:
Yousra Ajouaou, Abdulkader Azouz, Anaëlle Taquin, Sebastien Denanglaire, Hind Hussein, Mohammad Krayem, Fabienne Andris, Muriel Moser, Stanislas Goriely, Oberdan Leo
Publikováno v:
eLife, Vol 11 (2022)
The oxygen sensor prolyl hydroxylase domain 2 (PHD2) plays an important role in cell hypoxia adaptation by regulating the stability of HIF proteins (HIF1α and HIF2α) in numerous cell types, including T lymphocytes. The role of oxygen sensor on immu
Externí odkaz:
https://doaj.org/article/e1604c71c55a4360ab2ff987bcb3196f
Autor:
Aurore Demars, Armelle Vitali, Audrey Comein, Elodie Carlier, Abdulkader Azouz, Stanislas Goriely, Justine Smout, Véronique Flamand, Mégane Van Gysel, Johan Wouters, Jan Abendroth, Thomas E Edwards, Arnaud Machelart, Eik Hoffmann, Priscille Brodin, Xavier De Bolle, Eric Muraille
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009887 (2021)
Brucellosis is one of the most widespread bacterial zoonoses worldwide. Here, our aim was to identify the effector mechanisms controlling the early stages of intranasal infection with Brucella in C57BL/6 mice. During the first 48 hours of infection,
Externí odkaz:
https://doaj.org/article/0ebdeb0dee1242609d7b967c5f88f4d6
Autor:
Nicolas Istaces, Marion Splittgerber, Viviana Lima Silva, Muriel Nguyen, Séverine Thomas, Aurore Le, Younes Achouri, Emilie Calonne, Matthieu Defrance, François Fuks, Stanislas Goriely, Abdulkader Azouz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
T box transcription factor Eomesodermin (EOMES) is induced when naïve T cells are converted to innate memory T cells in response to cytokines. Here the authors show that EOMES is recruited to RUNX3-bound enhancers and interacts with BRG1 during inna
Externí odkaz:
https://doaj.org/article/977399acbe71487ca1c96fd6df9b2092
Autor:
Assiya Assabban, Ingrid Dubois-Vedrenne, Laurye Van Maele, Rosalba Salcedo, Brittany L. Snyder, Lecong Zhou, Abdulkader Azouz, Bérengère de Toeuf, Gaëlle Lapouge, Caroline La, Maxime Melchior, Muriel Nguyen, Séverine Thomas, Si Fan Wu, Wenqian Hu, Véronique Kruys, Cédric Blanpain, Giorgio Trinchieri, Cyril Gueydan, Perry J. Blackshear, Stanislas Goriely
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Cancer is caused primarily by genomic alterations resulting in deregulation of gene regulatory circuits in key growth, apoptosis, or DNA repair pathways. Multiple genes associated with the initiation and development of tumors are also regulated at th
Externí odkaz:
https://doaj.org/article/5f7e68b7fa75438a96e412ef4ca0c6e9
Autor:
Aurore Le, Abdulkader Azouz, Séverine Thomas, Nicolas Istaces, Muriel Nguyen, Stanislas Goriely
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
c-Jun N-terminal protein kinase 1 (JNK1) is involved in multiple biological processes but its implication in inflammatory skin diseases is still poorly defined. Herein, we studied the role of JNK1 in the context of Aldara®-induced skin inflammation.
Externí odkaz:
https://doaj.org/article/fe5537bf0f4341acbd216d3a77fb18fa