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CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury

Autor: Joy, Mary T., Ben Assayag, Einor, Shabashov-Stone, Dalia, Liraz-Zaltsman, Sigal, Mazzitelli, Jose, Arenas, Marcela, Abduljawad, Nora, Kliper, Efrat, Korczyn, Amos D., Thareja, Nikita S., Kesner, Efrat L., Zhou, Miou, Huang, Shan, Silva, Tawnie K., Katz, Noomi, Bornstein, Natan M., Silva, Alcino J., Shohami, Esther, Carmichael, S. Thomas

Publikováno v: In Cell 21 February 2019 176(5):1143-1157

Pharmacological Phosphodiesterase Inhibition as a Therapeutic for Cortical and Striatal Stroke

Autor: Abduljawad, Nora

Publikováno v: Abduljawad, Nora. (2019). Pharmacological Phosphodiesterase Inhibition as a Therapeutic for Cortical and Striatal Stroke. UCLA: Physiological Science 0671. Retrieved from: http://www.escholarship.org/uc/item/54r0986h

Stroke is the leading cause of adult disability, but there is no drug regimen available that promotes recovery after stroke. Recovery of function after stroke involves molecular signaling events mediated by cAMP and cGMP signaling, such as CREB activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::4041383386d8aa720c545b22a7fb82e9
http://www.escholarship.org/uc/item/54r0986h

CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury

Autor: Joy, Mary T, Ben Assayag, Einor, Shabashov-Stone, Dalia, Liraz-Zaltsman, Sigal, Mazzitelli, Jose, Arenas, Marcela, Abduljawad, Nora, Kliper, Efrat, Korczyn, Amos D, Thareja, Nikita S, Kesner, Efrat L, Zhou, Miou, Huang, Shan, Silva, Tawnie K, Katz, Noomi, Bornstein, Natan M, Silva, Alcino J, Shohami, Esther, Carmichael, S Thomas

Publikováno v: Cell, vol 176, iss 5

We tested a newly described molecular memory system, CCR5 signaling, for its role in recovery after stroke and traumatic brain injury (TBI). CCR5 is uniquely expressed in cortical neurons after stroke. Post-stroke neuronal knockdown of CCR5 in pre-mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0b3387c3babf54883349a8a9debdee62
https://escholarship.org/uc/item/0v7546ft

Correction to: Phosphodiesterase 10A Inhibition Leads to Brain Region-Specific Recovery Based on Stroke Type.

Autor: Birjandi, Shirin Z., Abduljawad, Nora, Nair, Shyama, Dehghani, Morteza, Suzuki, Kazunori, Kimura, Haruhide, Carmichael, S. Thomas

Publikováno v: Translational Stroke Research; Aug2021, Vol. 12 Issue 4, p691-691, 1p