Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man.

Autor: Flanagan SE; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK., De Franco E; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK., Lango Allen H; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK., Zerah M; Presbyterian Medical Group, Albuquerque, NM 87106, USA., Abdul-Rasoul MM; Faculty of Medicine, Department of Pediatrics, Kuwait University, Safat 13110, Kuwait., Edge JA; Oxford Children's Hospital, Headington, Oxford OX3 9DU, UK., Stewart H; Department of Clinical Genetics, Oxford University Hospitals NHS Trust, Oxford OX3 7LE, UK., Alamiri E; Al Qassimi Hospital, Sharjah 3500, United Arab Emirates., Hussain K; London Centre for Paediatric Endocrinology and Metabolism, Great Ormond Street Hospital for Children NHS Trust, and The Institute of Child Health, University College London, London WC1N 1EH, UK., Wallis S; Neonatal Unit, Bradford Royal Infirmary, Bradford BD9 6RJ, UK., de Vries L; Institute of Endocrinology and Diabetes, Schneider Children's Medical Center of Israel, PetahTikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 49202, Israel., Rubio-Cabezas O; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK; Department of Paediatric Endocrinology, Hospital Infantil Niño Jesús, Madrid 28009, Spain., Houghton JA; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK., Edghill EL; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK., Patch AM; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK., Ellard S; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK., Hattersley AT; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX2 5DW, UK. Electronic address: a.t.hattersley@exeter.ac.uk.

Publikováno v: Cell metabolism [Cell Metab] 2014 Jan 07; Vol. 19 (1), pp. 146-54.