Výsledky vyhledávání - "Abdul Quaiyoom Khan"

Akademický článek

Thymoquinone (2-Isoprpyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects

Autor: Anas Ahmad, Rakesh Kumar Mishra, Akshay Vyawahare, Ajay Kumar, Muneeb U. Rehman, Wajhul Qamar, Abdul Quaiyoom Khan, Rehan Khan

Publikováno v: Saudi Pharmaceutical Journal, Vol 27, Iss 8, Pp 1113-1126 (2019)

Cancer remains the topmost disorders of the mankind and number of cases is unceasingly growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the largest market in the modern treatment of cancer, natural agents have a

Externí odkaz: https://doaj.org/article/c580f589bdaa4aca980731b0a2765e9d

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Akademický článek

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia

Autor: Shilpa Kuttikrishnan, Kodappully S. Siveen, Kirti S. Prabhu, Abdul Quaiyoom Khan, Eiman I. Ahmed, Sabah Akhtar, Tayyiba A. Ali, Maysaloun Merhi, Said Dermime, Martin Steinhoff, Shahab Uddin

Publikováno v: Frontiers in Oncology, Vol 9 (2019)

Acute lymphoblastic leukemia (ALL) is a significant cancer of children resulting from the clonal proliferation of lymphoid precursors with arrested maturation. Although chemotherapeutic approaches have been achieving successful remission for the majo

Externí odkaz: https://doaj.org/article/85f85e533c8148c6949b21b668a3bd99

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Akademický článek

Ascorbic acid attenuates antineoplastic drug 5-fluorouracil induced gastrointestinal toxicity in rats by modulating the expression of inflammatory mediators

Autor: Abdulrahman Khazim Al-Asmari, Abdul Quaiyoom Khan, Amal Mohammad Al-Qasim, Yara Al-Yousef

Publikováno v: Toxicology Reports, Vol 2, Iss C, Pp 908-916 (2015)

Damage to the mucous membrane is a serious issue associated with chemotherapy. Gastrointestinal (GI) toxicity is complex and multistep process and unregulated production of reactive oxygen species (ROS) and inflammatory mediators play vital role in t

Externí odkaz: https://doaj.org/article/9b617d5cefd84ebd8b95bbfb06efa1ea

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Akademický článek

Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines

Autor: Kirti S. Prabhu, Kodappully S. Siveen, Shilpa Kuttikrishnan, Anh Jochebeth, Tayyiba A. Ali, Noor R. Elareer, Ahmad Iskandarani, Abdul Quaiyoom Khan, Maysaloun Merhi, Said Dermime, Tamam El-Elimat, Nicholas H. Oberlies, Feras Q. Alali, Martin Steinhoff, Shahab Uddin

Publikováno v: Biomolecules, Vol 9, Iss 4, p 126 (2019)

Greensporone A is a fungal secondary metabolite that has exhibited potential in vitro for anti-proliferative activity in vitro. We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. Greensporone A-mediated inhibition

Externí odkaz: https://doaj.org/article/b7f5dd6f3b204a5cacd21fbe41ef26e8

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Akademický článek

Moringa oleifera as an Anti-Cancer Agent against Breast and Colorectal Cancer Cell Lines.

Autor: Abdulrahman Khazim Al-Asmari, Sulaiman Mansour Albalawi, Md Tanwir Athar, Abdul Quaiyoom Khan, Hamoud Al-Shahrani, Mozaffarul Islam

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135814 (2015)

In this study we investigated the anti-cancer effect of Moringa oleifera leaves, bark and seed extracts. When tested against MDA-MB-231 and HCT-8 cancer cell lines, the extracts of leaves and bark showed remarkable anti-cancer properties while surpri

Externí odkaz: https://doaj.org/article/e45cee5cb88044cdb4b4c833b6681a41

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Akademický článek

Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats.

Autor: Rehan Khan, Abdul Quaiyoom Khan, Abdul Lateef, Muneeb U Rehman, Mir Tahir, Farrah Ali, Oday O Hamiza, Sarwat Sultana

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56020 (2013)

BACKGROUND: Colon carcinogenesis is a multistep process and it emanates from a series of molecular and histopathological alterations. Glycyrrhizic acid (GA) is a natural and major pentacyclic triterpenoid glycoside of licorice roots extracts. It has

Externí odkaz: https://doaj.org/article/5222625f32724617b522b6dc8aa7e2dd

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